Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Predominant T_H2-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma

1992 • 2,802 citations

Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs.

1993 • 1,270 citations

Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA

1984 • 973 citations

Mammalian lipoxygenases: molecular structures and functions

1992 • 571 citations

The alveolar macrophage

1986 • 509 citations

Release of Prostaglandin D₂into Human Airways during Acute Antigen Challenge

1986 • 476 citations

Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase.

1992 • 382 citations

Hydroxyeicosatetraenoic acids (HETEs)

1988 • 309 citations

Human alveolar macrophages produce leukotriene B4.

1982 • 278 citations

Characterization of the human B cell stimulatory factor 1 receptor.

1987 • 232 citations

Lipoxin A4 and Lipoxin B4 Inhibit Chemotactic Responses of Human Neutrophils Stimulated by Leukotriene B4 and N-Formyl-<scp>l</scp>-Methionyl-<scp>l</scp>-Leucyl-<scp>l</scp>-Phenylalanine

1989 • 220 citations

Molecular cloning and primary structure of human 15-lipoxygenase

1988 • 214 citations

Identification of a pharmacologically distinct prostaglandin H synthase in cultured epithelial cells.

1992 • 191 citations

Formation of lipoxins and leukotrienes during receptor-mediated interactions of human platelets and recombinant human granulocyte/macrophage colony-stimulating factor-primed neutrophils.

1990 • 180 citations

Selective incorporation of (15S)-hydroxyeicosatetraenoic acid in phosphatidylinositol of human neutrophils: agonist-induced deacylation and transformation of stored hydroxyeicosanoids.

1990 • 164 citations

The Effects of Lipoxin A₄on Airway Responses in Asthmatic Subjects

1992 • 154 citations

A serine esterase released by human alveolar macrophages is closely related to liver microsomal carboxylesterases.

1991 • 146 citations

Identification of Lipoxin A₄and Its Relationship to the Sulfidopeptide Leukotrienes C₄, D₄, and E₄in the Bronchoalveolar Lavage Fluids Obtained from Patients with Selected Pulmonary Diseases

1990 • 133 citations

Identification of 15–hydroxy‐5,8,11,13–eicosatetraenoic acid (15–HETE) as a major metabolite of arachidonic acid in human lung

1980 • 112 citations

Leukotriene C4 production by murine mast cells: evidence of a role for extracellular leukotriene A4.

1985 • 93 citations

Decreased leukotriene B4 synthesis in smokers' alveolar macrophages in vitro.

1986 • 91 citations

Synthesis of lipoxins and other lipoxygenase products by macrophages from the rainbow trout, Oncorhynchus mykiss

1991 • 85 citations

Lipoxin generation by permeabilized human platelets

1992 • 82 citations

Eicosanoid forming enzyme mRNA in human tissues. Analysis by quantitative polymerase chain reaction

1991 • 79 citations

Lipoxin A₄ inhibits leukotriene B₄,‐induced inflammation in the hamster cheek pouch

1989 • 77 citations

Lipoxin formation in human nasal polyps and bronchial tissue

1990 • 75 citations

15(S)-Hydroxyeicosatetraenoic acid is the major arachidonic acid metabolite in human bronchi: Association with airway epithelium

1990 • 60 citations

Lipoxins: Eicosanoids carrying intra-and intercellular messages

1991 • 54 citations

Formation and proliferative effects of lipoxins in human bone marrow

1991 • 53 citations

Formation of lipoxins and leukotrienes by human alveolar macrophages incubated with 15(S)-HETE: a model for cellular cooperation between macrophages and airway epithelial cells.

1992 • 33 citations

Lipoxins: Bioactive Lipoxygenase Interaction Products

1991 • 26 citations

Radioprotection of mouse hematopoietic stem cells by leukotriene A4 and lipoxin B4.

1988 • 21 citations

Determination of picogram amounts of lipoxin A4 and lipoxin B4 by high-performance liquid chromatography with electrochemical detection

1988 • 18 citations

Lipoxins and Other Lipoxygenase Products with Relevance to Inflammatory Reactions in the Lung^a

1991 • 12 citations

Lipoxin formation: evaluation of the role and actions of leukotriene A4.

1990 • 9 citations