Lipoxins: Eicosanoids carrying intra-and intercellular messages

Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

1983 • 2,839 citations

ARACHIDONIC ACID METABOLISM

1986 • 1,802 citations

Advances in prostaglandin, thromboxane, and leukotriene research

1985 • 759 citations

Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes.

1984 • 728 citations

Release of Prostaglandin D₂into Human Airways during Acute Antigen Challenge

1986 • 476 citations

Formation of leukotrienes and other hydroxy acids during platelet-neutrophil interactions in vitro

1982 • 308 citations

Lipoxin formation during human neutrophil-platelet interactions. Evidence for the transformation of leukotriene A4 by platelet 12-lipoxygenase in vitro.

1990 • 297 citations

Trihydroxytetraenes: A novel series of compounds formed from arachidonic acid in human leukocytes

1984 • 252 citations

Activation of protein kinase C by lipoxin A and other eicosanoids. Intracellular action of oxygenation products of arachidonic acid

1986 • 229 citations

Lipoxin A4 and Lipoxin B4 Inhibit Chemotactic Responses of Human Neutrophils Stimulated by Leukotriene B4 and N-Formyl-<scp>l</scp>-Methionyl-<scp>l</scp>-Leucyl-<scp>l</scp>-Phenylalanine

1989 • 220 citations

Selective activation of the γ‐subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites

1989 • 188 citations

Lipoxin A. Stereochemistry and biosynthesis.

1986 • 162 citations

Lipoxin A4 antagonizes cellular and in vivo actions of leukotriene D4 in rat glomerular mesangial cells: evidence for competition at a common receptor.

1989 • 153 citations

Identification of Lipoxin A₄and Its Relationship to the Sulfidopeptide Leukotrienes C₄, D₄, and E₄in the Bronchoalveolar Lavage Fluids Obtained from Patients with Selected Pulmonary Diseases

1990 • 133 citations

Identification of 15–hydroxy‐5,8,11,13–eicosatetraenoic acid (15–HETE) as a major metabolite of arachidonic acid in human lung

1980 • 112 citations

Transcellular conversion of endogenous arachidonic acid to lipoxins in mixed human platelet-granulocyte suspensions

1988 • 101 citations

On the stereochemistry and biosynthesis of lipoxin B.

1986 • 99 citations

Action of novel eicosanoids lipoxin A and B on human natural killer cell cytotoxicity: effects on intracellular cAMP and target cell binding.

1985 • 94 citations

Lipoxin A-induced inhibition of human natural killer cell cytotoxicity: studies on stereospecificity of inhibition and mode of action.

1987 • 92 citations

Lipoxins stimulate prostacyclin generation by human endothelial cells

1989 • 89 citations

New concepts in the modulation of leukotriene synthesis

1983 • 87 citations

Formation of lipoxin A by granulocytes from eosinophilic donors

1987 • 86 citations

Biological activities of Lipoxin A include lung strip contraction and dilation of arterioles in wiwo

1987 • 85 citations

Formation of leukotrienes and hydroxy acids by human neutrophils and platelets exposed to monosodium urate

1984 • 84 citations

On the relationship between leukotriene and lipoxin production by human neutrophils: evidence for differential metabolism of 15-HETE and 5-HETE

1989 • 82 citations

Enantiospecific and stereospecific synthesis of lipoxin A. Stereochemical assignment of the natural lipoxin A and its possible biosynthesis

1985 • 81 citations

Lipoxin A₄ inhibits leukotriene B₄,‐induced inflammation in the hamster cheek pouch

1989 • 77 citations

Formation of lipoxin B by the pure reticulocyte lipoxygenase via sequential oxygenation of the substrate

1987 • 64 citations

Lipoxin A₄ and lipoxin B₄ stimulate the release but not the oxygenation of arachidonic acid in human neutrophils: Dissociation between lipid remodeling and adhesion

1990 • 64 citations

The lipoxins. Stereochemical identification and determination of their biosynthesis.

1985 • 54 citations

The action of Lipoxin-A on glomerular microcirculatory dynamics in the rat

1987 • 53 citations

Lipoxin synthesis by arachidonate 5-lipoxygenase purified from porcine leukocytes

1987 • 53 citations

Prostaglandins in cancer research

1988 • 50 citations

Lipoxins A4 and B4: comparison of icosanoids having bronchoconstrictor and vasodilator actions but lacking platelet aggregatory activity.

1988 • 49 citations

A stereoselective and practical synthesis of 5,6(S,S)-epoxy-15(S)-hydroxy-7(E),9(E),11(Z),13(E)-eicosatetraenoic acid (4), possible precursor of the lipoxins

1986 • 45 citations

The effects of lipoxin A and lipoxin B on functional responses of human granulocytes

1987 • 45 citations

Evidence for a 5(6)‐epoxytetraene intermediate in the biosynthesis of lipoxins in human leukocytes

1986 • 37 citations

Nomenclature of lipoxins and related compounds derived from arachidonic acid and eicosapentaenoic acid

1987 • 33 citations

Lipoxin synthesis by arachidonate 12-lipoxygenase purified from porcine leukocytes

1987 • 30 citations

Ca2+ mobilization with leukotriene A4 and epoxytetraenes in human neutrophils

1990 • 27 citations

Formation of lipoxins by alveolar macrophages

1988 • 27 citations

Formation of lipoxin B by the pure reticulocyte lipoxygenase

1986 • 26 citations

The contractile activities of lipoxin A₄ and lipoxin B₄ for guinea‐pig airway tissues

1988 • 25 citations

Identification of a novel 7-cis-11-trans-lipoxin A4 generated by human neutrophils: total synthesis, spasmogenic activities and comparison with other geometric isomers of lipoxins A4 and B4

1989 • 25 citations

The formation of products containing a conjugated tetraenoic system by pure reticulocyte lipoxygenase

1984 • 24 citations

A phospholipase A2 isoenzyme provokes lipoxin B formation from endogenous sources of arachidonic acid in porcine leukocytes

1987 • 23 citations

Radioprotection of mouse hematopoietic stem cells by leukotriene A4 and lipoxin B4.

1988 • 21 citations

New series of lipoxins isolated from human eosinophils

1989 • 21 citations

Transformation of leukotriene A4 to lipoxins by rat kidney mesangial cell

1989 • 21 citations

Synthesis of 5S-hydroxy-14, 15 LTA4 a biogenic precursor to the lipoxins

1987 • 18 citations

Mesenteric vascular responses to i.v. administration of lipoxin A₄ and lipoxin B₄ in the conscious rat

1988 • 18 citations

Evidence for lipoxin formation by bovine polymorphonuclear leukocytes via triple dioxygenation of arachidonic acid

1988 • 18 citations

Lipoxins A4 and B4 dilate cerebral arterioles of newborn pigs

1989 • 18 citations

15-Hydroxyeicosatetraenoic Acid Inhibits Superoxide Anion Generation by Human Neutrophils: Relationship to Lipoxin Production

1989 • 15 citations

Pharmacodynamics of lipoxin A4 in airway smooth muscle

1989 • 15 citations

Lipoxin A4 causes generation of thromboxane A2 in the guinea-pig lung

1989 • 14 citations

Comparative activity of leukotriene D4, 5,6-dihydroxy-eicosatetraenoic acid and lipoxin A on guinea pig lung parenchyma and ileum smooth muscle.

1988 • 8 citations

Agonist-dependent generation of lipoxins from rat basophilic leukemia cell (RBL-1)

1989 • 8 citations

On the Formation and Biological Role of Leukotrienes and Lipoxins

1987 • 4 citations

Deleted Work

1955 • 0 citations