Signals involved in T cell activation. T cell proliferation induced through the synergistic action of anti‐CD28 and anti‐CD2 monoclonal antibodies

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

Early Signals in the Mitogenic Response

1986 • 1,498 citations

An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein

1984 • 1,132 citations

Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.

1983 • 833 citations

OKT3: A monoclonal anti-human T lymphocyte antibody with potent mitogenic properties

1980 • 718 citations

OKT3: a monoclonal anti-human T lymphocyte antibody with potent mitogenic properties.

1980 • 525 citations

Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway.

1984 • 506 citations

Monoclonal antibodies identifying a novel T-Cell antigen and Ia antigens of human lymphocytes

1980 • 326 citations

Does OKT3 monoclonal antibody react with an antigen-recognition structure on human T cells?

1981 • 306 citations

Conjugation of fluorescein isothiocyanate to antibodies. I. Experiments on the conditions of conjugation.

1970 • 300 citations

Human T cell activation. II. A new activation pathway used by a major T cell population via a disulfide-bonded dimer of a 44 kilodalton polypeptide (9.3 antigen).

1985 • 285 citations

Blockade of the interleukin-2 receptor by anti-Tac antibody: inhibition of human lymphocyte activation.

1983 • 250 citations

Antibodies to Tp67 and Tp44 augment and sustain proliferative responses of activated T cells.

1985 • 218 citations

The T3 complex on human T lymphocytes involves four structurally distinct glycoproteins.

1983 • 194 citations

A 44 kilodalton cell surface homodimer regulates interleukin 2 production by activated human T lymphocytes.

1986 • 191 citations

Antibody binding to CD5 (Tp67) and Tp44 T cell surface molecules: effects on cyclic nucleotides, cytoplasmic free calcium, and cAMP-mediated suppression.

1986 • 166 citations

Synergy between the T3/antigen receptor complex and Tp44 in the activation of human T cells.

1986 • 165 citations

A common pathway for T lymphocyte activation involving both the CD3-Ti complex and CD2 sheep erythrocyte receptor determinants.

1986 • 163 citations

Human T cell activation. I. Monocyte-independent activation and proliferation induced by anti-T3 monoclonal antibodies in the presence of tumor promoter 12-o-tetradecanoyl phorbol-13 acetate.

1985 • 155 citations

T cell activation via CD2 [T, gp50] molecules: accessory cells are required to trigger T cell activation via CD2-D66 plus CD2-9.6/T11(1) epitopes.

1985 • 150 citations

Involvement of T44 molecules in an antigen-independent pathway of T cell activation. Analysis of the correlations to the T cell antigen-receptor complex.

1985 • 142 citations

Soluble antigen-primed inducer T cells activate antigen-specific suppressor T cells in the absence of antigen-pulsed accessory cells: phenotypic definition of suppressor-inducer and suppressor-effector cells.

1984 • 121 citations

The δ- and ε-chains of the human T3/T-cell receptor complex are distinct polypeptides

1984 • 113 citations

The T11 glycoprotein is functionally linked to a calcium channel in precursor and mature T-lineage cells.

1986 • 98 citations

Transmembrane signalling by the T3-antigen receptor complex

1985 • 82 citations

T cell stimulation via the erythrocyte receptor. Synergism between monoclonal antibodies and phorbol myristate acetate without changes of free cytoplasmic Ca++ levels.

1986 • 81 citations

Anti‐CD2 (sheep red blood cell receptor) monoclonal antibodies and T cell activation I. Pairs of anti‐T11.1 and T11.2 (CD2 subgroups) are strongly mitogenic for T cells in presence of 12‐O‐tetradecanoylphorbol 13‐acetate

1986 • 81 citations

In vitro regulation of immunoglobulin synthesis by T-cell subpopulations defined by a new human T-cell antigen (9.3)

1982 • 65 citations

T90/44 (9.3 antigen). A cell surface molecule with a function in human T cell activation

1986 • 60 citations

Amplification of the immune response by agonistic antibodies

1986 • 44 citations

The role of the T3 molecular complex in antigen recognition and subsequent activation events

1984 • 41 citations

A unique epitope on the CD2 molecule defined by the monoclonal antibody 9-1: epitope-specific modulation of the E-rosette receptor and effects on T-cell functions

1986 • 36 citations

Signal transducing mechanisms involved in human T cell activation via surface T44 molecules. Comparison with signals transduced via the T cell receptor complex

1986 • 28 citations

Biochemical characterization of the 9.3 antigens of human T-cells: Simultaneous expression of disulfide-bonded 90-kilodalton dimers and free subunits at the cell surface

1986 • 20 citations

Interleukin 2 induces T cell‐dependent IgM production in human B cells

1985 • 14 citations