Evaluation of HER-2 neu oncoprotein expression as a prognostic indicator of local recurrence in conservatively treated breast cancer: A case-control study

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

Five-Year Results of a Randomized Clinical Trial Comparing Total Mastectomy and Segmental Mastectomy with or without Radiation in the Treatment of Breast Cancer

1985 • 2,186 citations

Eight-Year Results of a Randomized Clinical Trial Comparing Total Mastectomy and Lumpectomy with or without Irradiation in the Treatment of Breast Cancer

1989 • 1,604 citations

Pathologic findings from the National Surgical Adjuvant Breast and Bowel Project: prognostic significance of erbB-2 protein overexpression in primary breast cancer.

1990 • 602 citations

Significance of ipsilateral breast tumour recurrence after lumpectomy

1991 • 556 citations

Local Recurrences and Distant Metastases After Conservative Breast Cancer Treatments: Partly Independent Events

1995 • 511 citations

The relationship between microscopic margins of resection and the risk of local recurrence in patients with breast cancer treated with breast-conserving surgery and radiation therapy

1994 • 482 citations

HER-2/neu in node-negative breast cancer: prognostic significance of overexpression influenced by the presence of in situ carcinoma.

1992 • 466 citations

HER-2/neu amplification predicts poor survival in node-positive breast cancer.

1990 • 456 citations

The presence of an extensive intraductal component following a limited excision correlates with prominent residual disease in the remainder of the breast.

1990 • 451 citations

Pathologic predictors of early local recurrence in stage I and II breast cancer treated by primary radiation therapy

1984 • 360 citations

Breast recurrence following conservative surgery and radiation: patterns of failure, prognosis, and pathologic findings from mastectomy specimens with implications for treatment

1990 • 343 citations

c-erbB-2 protein overexpression in breast cancer is a risk factor in patients with involved and uninvolved lymph nodes

1991 • 335 citations

Follow-up study of HER-2/neu amplification in primary breast cancer.

1991 • 268 citations

Correlation between c-erbB-2 amplification and risk of recurrent disease in node-negative breast cancer.

1991 • 267 citations

Why are local recurrences after breast-conserving therapy more frequent in younger patients?

1990 • 260 citations

Ten year results of conservative surgery and irradiation for stage I and II breast cancer

1991 • 249 citations

Ipsilateral breast tumor recurrence as a predictor of distant disease: implications for systemic therapy at the time of local relapse.

1996 • 197 citations

A clinical and histopathologic analysis of the results of conservation surgery and radiation therapy in stage I and II breast carcinoma

1986 • 142 citations

An assessment of extensive intraductal component as a risk factor for local recurrence after breast-conserving therapy

1990 • 110 citations

Local recurrence versus new primary: Clinical analysis of 82 breast relapses and potential applications for genetic fingerprinting

1993 • 102 citations

Prognostic factors for local recurrence in the conservatively treated breast cancer patient: a cautious interpretation of the data.

1991 • 98 citations

Eight-Year Results of a Randomized Clinical Trial Comparing Total Mastectomy and Lumpectomy with or without Irradiation in the Treatment of Breast Cancer

1989 • 88 citations

Premenopausal breast cancer patients treated with conservative surgery, radiotherapy and adjuvant chemotherapy have a low risk of local failure

1989 • 72 citations

Is C-ERB B-2 a predictor for recurrent disease in early stage breast cancer?

1994 • 23 citations