Induction of 6-thioguanine-resistant mutations by rat-liver homogenate (S9)-activated promutagens in human embryonic skin fibroblasts

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Methods for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test

1975 • 7,413 citations

Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture.

1970 • 1,464 citations

Epoxides in Polycyclic Aromatic Hydrocarbon Metabolism and Carcinogenesis

1974 • 739 citations

Progress in Genetic Toxicology

1978 • 581 citations

DNA excision-repair processes in human cells can eliminate the cytotoxic and mutagenic consequences of ultraviolet irradiation

1979 • 245 citations

Cell‐mediated mutagenesis of mammalian cells with chemical carcinogens

1974 • 243 citations

Resistance of cultured human fibroblasts and other cells to purine and pyrimidine analogues in relation to mutagenesis detection

1974 • 174 citations

Liver homogenate-mediated mutagenesis in Chinese hamster V79 cells by polycyclic aromatic hydrocarbons and aflatoxins

1977 • 150 citations

Mutability of different genetic loci in mammalian cells by metabolically activated carcinogenic polycyclic hydrocarbons.

1976 • 148 citations

Liver cell-mediated mutagenesis of mammalian cells by liver carcinogens.

1978 • 138 citations

Comparison of the cellular DNA-bound products of benzo(alpha)pyrene with the products formed by the reaction of benzo(alpha)pyrene-4,5-oxide with DNA.

1975 • 113 citations

Differences in effects of norharman with various classes of chemical mutagens and amounts of S-9

1978 • 106 citations

Limitations of Metabolic Activation Systems Used with in Vitro Tests for Carcinogens

1980 • 106 citations

Microsome-mediated mutagenesis in V79 Chinese hamster cells by various nitrosamines.

1977 • 102 citations

Ultraviolet light induction of diphtheria toxin-resistant mutants of normal and xeroderma pigmentosum human fibroblasts.

1979 • 79 citations

Ultraviolet mutagenesis of normal and xeroderma pigmentosum variant human fibroblasts

1979 • 76 citations

Quantification of chemical mutagenesis in diploid human fibroblasts: Induction of azaguanine-resistant mutants by N-methyl-N′-nitro-N-nitrosoguanidine

1978 • 76 citations

X-ray-induced mutation to 6-thioguanine resistance in cultured human diploid fibroblasts

1976 • 76 citations

Critical importance of microsome concentration in mutagenesis assay with V79 Chinese hamster cells

1979 • 74 citations

Cell-mediated mutagenesis in cultured Chinese hamster cells by carcinogenic polycyclic hydrocarbons: Nature and extent of the associated hydrocarbon-DNA reaction

1977 • 71 citations

Induction of sister chromatid exchanges in Chinese hamster cells by carcinogenic mutagens requiring metabolic activation

1977 • 66 citations

The relation between induced mutation frequency and cell survival — A theoretical approach and an examination of experimental data for eukaryotes

1977 • 59 citations

Mutations to azaguanine resistance induced in cultured diploid human fibroblasts by the carcinogen, N-acetoxy-2-Acetylaminofluorene

1975 • 52 citations

Mutagenicity of dimethylnitrosamine to mammalian cells as determined by the use of mouse liver microsomes

1975 • 49 citations

Mutagenesis at the ouabain-resistance locus in human diploid fibroblasts

1977 • 47 citations

Human bronchus-mediated mutagenesis of mammalian cells by carcinogenic polynuclear aromatic hydrocarbons.

1978 • 46 citations

Some factors determining the concentration of liver proteins for optimal mutagenicity of chemicals in the salmonella/microsome assay

1979 • 45 citations

Induction of 6-thioguanine-resistant mutants in V79 Chinese hamster cells by mouse-liver microsome-activated dimethylnitrosamine

1977 • 42 citations

Human cell-mediated benzo(a)pyrene cytotoxicity and mutagenicity in human diploid fibroblasts.

1980 • 34 citations

Mutagenicity and cytotoxicity of nineteen heterocyclic mustards (ICR compounds) in cultured mammalian cells.

1979 • 31 citations

Retention of tritium during the binding of tritiated benzo(a)pyrene to DNA

1975 • 29 citations

A benzo[a]pyrene -7,8-dihydrodiol-9,10-epoxide is the major metabolite involved in the binding of benzo[a]pyrene to DNA in isolated viable rat hepatocytes

1980 • 28 citations

Mutation of Human Cells by Kerosene Soot<xref ref-type="fn" rid="FN2">2</xref>

1979 • 26 citations

Mutagenicity of furylfuramide, a food preservative, tested by using alanine-requiring mouse L5178Y cells in vitro and in vivo

1977 • 17 citations

The nature of benzo[a]pyrene binding to DNA in an epithelial cell culture system

1976 • 14 citations

Comparison between sister-chromatid exchange and mutagenicity following exogenous metabolic activation of promutagens

1981 • 14 citations

Analysis of intracellular distribution and binding of benzo[a]pyrene in human diploid fibroblasts

1980 • 12 citations

Induction of 6-thioguanine resistance in human cells treated with N-acetoxy-2-acetylaminofluorene

1978 • 10 citations

Induction of 6-thioguanine resistance in human cells treated with N-acetoxy-2-acetylaminofluorene

1978 • 10 citations

Mutation studies with human fibroblasts.

1973 • 6 citations

The scientific imperative for use of human cells and organs in vitro: Comparative toxicology and oncogenesis

1977 • 4 citations