CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanism
Data up to Jan 2025
Total Citations Per Year
Abstract
References (39)
New Perspectives in Cell Adhesion: RGD and Integrins
1987 • 4,835 citations
CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells
1998 • 2,047 citations
Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways
1996 • 1,457 citations
CD40-CD40 ligand
2000 • 1,376 citations
The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation
1994 • 1,099 citations
Blood-borne tissue factor: Another view of thrombosis
1999 • 982 citations
Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates
1999 • 824 citations
β3-integrin–deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival
1999 • 731 citations
The CD40/CD154 receptor/ligand dyadRID="†"ID="†" Review
2001 • 730 citations
Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand
2000 • 646 citations
P-selectin induces the expression of tissue factor on monocytes.
1994 • 595 citations
A mouse model of severe von Willebrand disease: Defects in hemostasis and thrombosis
1998 • 512 citations
Enhanced Levels of Soluble and Membrane-Bound CD40 Ligand in Patients With Unstable Angina
1999 • 504 citations
Activation of Monocyte/Macrophage Functions Related to Acute Atheroma Complication by Ligation of CD40
1997 • 493 citations
Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen
2000 • 490 citations
Ligands “activate” integrin αIIbβ3 (platelet GPIIb-IIIa)
1991 • 481 citations
Requirement for CD154 in the progression of atherosclerosis
1999 • 437 citations
The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40
2001 • 430 citations
Platelet Membrane Defects in Glanzmann's Thrombasthenia
1977 • 391 citations
Barbourin. A GPIIb-IIIa-specific integrin antagonist from the venom of Sistrurus m. barbouri
1991 • 373 citations
Design of potent and specific integrin antagonists. Peptide antagonists with high specificity for glycoprotein IIb-IIIa.
1993 • 369 citations
Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice
2000 • 353 citations
Pro-coagulant state resulting from high levels of soluble P-selectin in blood
2000 • 315 citations
Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins
2000 • 300 citations
Both early and delayed anti-CD40L antibody treatment induces a stable plaque phenotype
2000 • 263 citations
A soluble form of TRAP (CD40 ligand) is rapidly released after T cell activation
1995 • 252 citations
Role of Platelet P-Selectin and CD40 Ligand in the Induction of Monocytic Tissue Factor Expression
2000 • 239 citations
Inhibition of fibrinogen binding to GP IIb-IIIa by a GP IIIa peptide
1991 • 221 citations
Ligation of CD40 induces the expression of vascular endothelial growth factor by endothelial cells and monocytes and promotes angiogenesis in vivo
2000 • 190 citations
An integrin receptor on normal and thrombasthenic platelets that binds thrombospondin [see comments]
1989 • 158 citations
CD40L-CD40 interactions regulate endothelial cell surface tissue factor and thrombomodulin expression
1998 • 157 citations
High-Affinity Interactions of Tumor Necrosis Factor Receptor-Associated Factors (TRAFs) and CD40 Require TRAF Trimerization and CD40 Multimerization
1999 • 154 citations
Primary immunodeficiency diseases. A molecular and genetic approach.
1999 • 130 citations
An integrin receptor on normal and thrombasthenic platelets that binds thrombospondin [see comments]
1989 • 119 citations
Biological function of CD40 on human endothelial cells: costimulation with CD40 ligand and interleukin‐4 selectively induces expression of vascular cell adhesion molecule‐1 and P‐selectin resulting in preferential adhesion of lymphocytes
2000 • 108 citations
Growth and Stability of Thrombi in Flowing Citrated Blood: Assessment of Platelet-Surface Interactions with Computer-Assisted Morphometry
1988 • 62 citations
EVIDENCE FOR DECREASED AMOUNTS OF TWO MAJOR GLYCOPROTEINS
1977 • 31 citations
Optimal Antagonism of GPIIb/IIIa Favors Platelet Adhesion by Inhibiting Thrombus Growth
1996 • 29 citations
Deleted Work
1955 • 0 citations