Back to search

CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanism

Data up to Jan 2025

Published2002
Citations722
References39

Total Citations Per Year

Abstract

References (39)

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells

1998 • 2,047 citations

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

1996 • 1,457 citations

CD40-CD40 ligand

2000 • 1,376 citations

The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation

1994 • 1,099 citations

Blood-borne tissue factor: Another view of thrombosis

1999 • 982 citations

Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates

1999 • 824 citations

β3-integrin–deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival

1999 • 731 citations

The CD40/CD154 receptor/ligand dyadRID="†"ID="†" Review

2001 • 730 citations

Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand

2000 • 646 citations

P-selectin induces the expression of tissue factor on monocytes.

1994 • 595 citations

A mouse model of severe von Willebrand disease: Defects in hemostasis and thrombosis

1998 • 512 citations

Enhanced Levels of Soluble and Membrane-Bound CD40 Ligand in Patients With Unstable Angina

1999 • 504 citations

Activation of Monocyte/Macrophage Functions Related to Acute Atheroma Complication by Ligation of CD40

1997 • 493 citations

Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen

2000 • 490 citations

Ligands “activate” integrin αIIbβ3 (platelet GPIIb-IIIa)

1991 • 481 citations

Requirement for CD154 in the progression of atherosclerosis

1999 • 437 citations

The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40

2001 • 430 citations

Platelet Membrane Defects in Glanzmann's Thrombasthenia

1977 • 391 citations

Barbourin. A GPIIb-IIIa-specific integrin antagonist from the venom of Sistrurus m. barbouri

1991 • 373 citations

Design of potent and specific integrin antagonists. Peptide antagonists with high specificity for glycoprotein IIb-IIIa.

1993 • 369 citations

Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice

2000 • 353 citations

Pro-coagulant state resulting from high levels of soluble P-selectin in blood

2000 • 315 citations

Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins

2000 • 300 citations

Both early and delayed anti-CD40L antibody treatment induces a stable plaque phenotype

2000 • 263 citations

A soluble form of TRAP (CD40 ligand) is rapidly released after T cell activation

1995 • 252 citations

Role of Platelet P-Selectin and CD40 Ligand in the Induction of Monocytic Tissue Factor Expression

2000 • 239 citations

Inhibition of fibrinogen binding to GP IIb-IIIa by a GP IIIa peptide

1991 • 221 citations

Ligation of CD40 induces the expression of vascular endothelial growth factor by endothelial cells and monocytes and promotes angiogenesis in vivo

2000 • 190 citations

An integrin receptor on normal and thrombasthenic platelets that binds thrombospondin [see comments]

1989 • 158 citations

CD40L-CD40 interactions regulate endothelial cell surface tissue factor and thrombomodulin expression

1998 • 157 citations

High-Affinity Interactions of Tumor Necrosis Factor Receptor-Associated Factors (TRAFs) and CD40 Require TRAF Trimerization and CD40 Multimerization

1999 • 154 citations

Primary immunodeficiency diseases. A molecular and genetic approach.

1999 • 130 citations

An integrin receptor on normal and thrombasthenic platelets that binds thrombospondin [see comments]

1989 • 119 citations

Biological function of CD40 on human endothelial cells: costimulation with CD40 ligand and interleukin‐4 selectively induces expression of vascular cell adhesion molecule‐1 and P‐selectin resulting in preferential adhesion of lymphocytes

2000 • 108 citations

Growth and Stability of Thrombi in Flowing Citrated Blood: Assessment of Platelet-Surface Interactions with Computer-Assisted Morphometry

1988 • 62 citations

EVIDENCE FOR DECREASED AMOUNTS OF TWO MAJOR GLYCOPROTEINS

1977 • 31 citations

Optimal Antagonism of GPIIb/IIIa Favors Platelet Adhesion by Inhibiting Thrombus Growth

1996 • 29 citations

Deleted Work

1955 • 0 citations

Cited By (0)

Loading...
CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanism (2002) – Nature Medicine | Metascience Observatory Explorer