Occludin is required for apoptosis when claudin–claudin interactions are disrupted

Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry

2007 • 1,182 citations

Complex Phenotype of Mice Lacking Occludin, a Component of Tight Junction Strands

2000 • 1,118 citations

Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease

2006 • 1,116 citations

Clostridium perfringens Enterotoxin Fragment Removes Specific Claudins from Tight Junction Strands

1999 • 609 citations

Occludin-deficient Embryonic Stem Cells Can Differentiate into Polarized Epithelial Cells Bearing Tight Junctions

1998 • 532 citations

Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells

2005 • 451 citations

Loss of tight junction barrier function and its role in cancer metastasis

2008 • 443 citations

Tight junctions are membrane microdomains

2000 • 430 citations

Induction of gastric epithelial apoptosis by Helicobacter pylori.

1996 • 425 citations

Molecular Ordering of the Initial Signaling Events of CD95

2002 • 387 citations

Epithelial Tight Junctions in Intestinal Inflammation

2009 • 381 citations

Tight Junction Proteins Claudin-1 and Occludin Control Hepatitis C Virus Entry and Are Downregulated during Infection To Prevent Superinfection

2008 • 340 citations

Interferon‐γ induces internalization of epithelial tight junction proteins via a macropinocytosis‐like process

2005 • 340 citations

Increase in proliferation and apoptosis of gastric epithelial cells early in the natural history of Helicobacter pylori infection.

1997 • 276 citations

Apoptosis in hepatitis C virus infection

2003 • 146 citations

Alteration of Tight Junction Proteins Is an Early Event in Psoriasis

2009 • 141 citations

Occludin expression decreases with the progression of human endometrial carcinoma

2004 • 126 citations

Hepatitis C virus envelope components alter localization of hepatocyte tight junction-associated proteins and promote occludin retention in the endoplasmic reticulum

2008 • 104 citations

Loss of occludin leads to the progression of human breast cancer

2010 • 101 citations

CD95 death‐inducing signaling complex formation and internalization occur in lipid rafts of type I and type II cells

2004 • 99 citations

Methyl-β-Cyclodextrin Increases Permeability of Caco-2 Cell Monolayers by Displacing Specific Claudins from Cholesterol Rich Domains Associated with Tight Junctions

2007 • 67 citations

Interleukin-1 receptor phosphorylation activates Rho kinase to disrupt human gastric tight junctional claudin-4 duringHelicobacter pyloriinfection

2010 • 47 citations

Occludin‐mediated premature senescence is a fail‐safe mechanism against tumorigenesis in breast carcinoma cells

2007 • 43 citations

Disruption of occludin function in polarized epithelial cells activates the extrinsic pathway of apoptosis leading to cell extrusion without loss of transepithelial resistance

2009 • 38 citations

A d-Peptide Analog of the Second Extracellular Loop of Claudin-3 and -4 Leads to MisLocalized Claudin and Cellular Apoptosis in Mammary Epithelial Cells

2010 • 29 citations