Conservation of dorsal-ventral patterning in arthropods and chordates

Novel Regulators of Bone Formation: Molecular Clones and Activities

1988 • 3,919 citations

DPC4 , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1

1996 • 2,320 citations

Mechanism of activation of the TGF-β receptor

1994 • 2,298 citations

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms.

1994 • 1,950 citations

The origin of pattern and polarity in the Drosophila embryo

1992 • 1,367 citations

Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos

1992 • 1,176 citations

Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes

1994 • 1,114 citations

Direct and Long-Range Action of a DPP Morphogen Gradient

1996 • 896 citations

über Induktion von Embryonalanlagen durch Implantation artfremder Organisatoren

1924 • 817 citations

Induction of epidermis and inhibition of neural fate by Bmp-4

1995 • 782 citations

A common plan for dorsoventral patterning in Bilateria

1996 • 774 citations

A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family

1987 • 756 citations

Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus

1995 • 731 citations

MADR1, a MAD-Related Protein That Functions in BMP2 Signaling Pathways

1996 • 710 citations

The zootype and the phylotypic stage

1993 • 689 citations

Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster.

1995 • 672 citations

Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development

1992 • 573 citations

The TGF-β family and its composite receptors

1994 • 539 citations

Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components.

1996 • 528 citations

DVR-4 (Bone Morphogenetic Protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction

1992 • 488 citations

decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo

1992 • 480 citations

Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo

1994 • 463 citations

A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo.

1994 • 449 citations

A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin

1995 • 436 citations

Xenopus Mad Proteins Transduce Distinct Subsets of Signals for the TGFβ Superfamily

1996 • 432 citations

über Induktion von Embryonalanlagen durch Implantation artfremder Organisatoren

1924 • 429 citations

Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo

1995 • 419 citations

On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo.

1994 • 396 citations

Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction.

1995 • 368 citations

Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm

1993 • 365 citations

SIGNALING PATHWAYS THAT ESTABLISH THE DORSAL-VENTRAL PATTERN OF THE DROSOPHILA EMBRYO

1995 • 348 citations

Ventral mesodermal patterning in Xenopus embryos: Expression patterns and activities of BMP‐2 and BMP‐4

1995 • 344 citations

Characterization and relationship of dpp receptors encoded by the saxophone and thick veins genes in Drosophila

1994 • 317 citations

An absolute requirement for both the type II and type I receptors, punt and thick veins, for Dpp signaling in vivo

1995 • 312 citations

Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene.

1994 • 307 citations

Genetic screens to identify elements of the decapentaplegic signaling pathway in Drosophila.

1995 • 306 citations

Early cellular interactions promote embryonic axis formation in Xenopus laevis

1984 • 291 citations

The decapentaplegic gene is required for dorsal-ventral patterning of the Drosophila embryo.

1987 • 288 citations

Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo.

1993 • 283 citations

An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo

1993 • 283 citations

Drosophila Dpp signaling is mediated by the punt gene product: A dual ligand-binding type II receptor of the TGFβ receptor family

1995 • 275 citations

Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic

1994 • 275 citations

Dorsalization and neural induction: properties of the organizer in Xenopus laevis.

1983 • 267 citations

Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor

1994 • 254 citations

The formation of the mesoderm in urodelean amphibians

1973 • 247 citations

Decapentaplegic transcripts are localized along the dorsal-ventral axis of the Drosophila embryo.

1987 • 247 citations

The control of cell fate along the dorsal-ventral axis of the Drosophila embryo

1991 • 246 citations

Inducing factors in Xenopus early embryos

1994 • 234 citations

Neural differentiation of Xenopus laevis ectoderm takes place after disaggregation and delayed reaggregation without inducer

1989 • 232 citations

Localized BMP-4 Mediates Dorsal/Ventral Patterning in the Early Xenopus Embryo

1995 • 229 citations

dpp induces mesodermal gene expression in Drosophila

1994 • 224 citations

Localized enhancement and repression of the activity of the TGF-P family member, decapentaplegic, is necessary for dorsal-ventral pattern formation in the Drosophila embryo

1992 • 222 citations

The screw gene encodes a ubiquitously expressed member of the TGF-beta family required for specification of dorsal cell fates in the Drosophila embryo.

1994 • 199 citations

The development of animal cap cells in Xenopus: a measure of the start of animal cap competence to form mesoderm

1987 • 187 citations

Mothers against dpp encodes a conserved cytoplasmic protein required in DPP/TGF-β responsive cells

1996 • 174 citations

Bone morphogenetic protein 4 (BMP-4), a member of the TGF-β family, in early embryos of Xenopus laevis: analysis of mesoderm inducing activity

1991 • 167 citations

Subcortical rotation in Xenopus eggs: An early step in embryonic axis specification

1987 • 162 citations

A truncated bone morphogenetic protein 4 receptor alters the fate of ventral mesoderm to dorsal mesoderm: roles of animal pole tissue in the development of ventral mesoderm.

1994 • 162 citations

Competition between noggin and bone morphogenetic protein 4 activities may regulate dorsalization during Xenopus development.

1995 • 161 citations

Bone morphogenetic protein-4 (BMP-4) acts during gastrula stages to cause ventralization of Xenopus embryos

1996 • 143 citations

The role of gsc and BMP-4 in dorsal-ventral patterning of the marginal zone in Xenopus: a loss-of-function study using antisense RNA.

1995 • 137 citations

Clonal analysis of mesoderm induction in Xenopus laevis

1989 • 134 citations

The Drosophila saxophone Gene: a Serine-Threonine Kinase Receptor of the TGF-β Superfamily

1994 • 131 citations

A Dominant Negative Bone Morphogenetic Protein 4 Receptor Causes Neuralization in Xenopus Ectoderm

1995 • 127 citations

Altered mitotic domains reveal fate map changes in Drosophila embryos mutant for zygotic dorsoventral patterning genes

1992 • 119 citations

Mesoderm induction in Xenopus laevis: a quantitative study using a cell lineage label and tissue-specific antibodies

1985 • 105 citations

Is ventral in insects dorsal in vertebrates?

1994 • 92 citations

Signaling Pathways that Establish the Dorsal-Ventral Pattern of the Drosophila Embryo

1995 • 86 citations

Drosophila short gastrulation induces an ectopic axis in Xenopus: evidence for conserved mechanisms of dorsal-ventral patterning

1995 • 76 citations

Bone morphogenetic protein acts as a ventral mesoderm modifier in early Xenopus embryos

1995 • 47 citations

Johannes Holtfreter's contributions to ongoing studies of the organizer

1996 • 16 citations