In vitro evaluation of Taxol® combined with radiations in human squamous cell carcinoma spheroids

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

1984 • 6,841 citations

Taxol stabilizes microtubules in mouse fibroblast cells.

1980 • 1,942 citations

Cell and Environment Interactions in Tumor Microregions: The Multicell Spheroid Model

1988 • 1,755 citations

Exploitable mechanisms in combined radiotherapy-chemotherapy: The concept of additivity

1979 • 912 citations

X-Ray Sensitivity during the Cell Generation Cycle of Cultured Chinese Hamster Cells

1966 • 540 citations

Inherent cellular radiosensitivity as a basic concept for human tumor radiotherapy

1981 • 530 citations

A simplified method for production and growth of multicellular tumor spheroids.

1977 • 501 citations

Taxol: an antimitotic agent with a new mechanism of action

1984 • 483 citations

Multicellular spheroids

1987 • 427 citations

Mean Inactivation Dose: A Useful Concept for Intercomparison of Human Cell Survival Curves

2012 • 361 citations

Mean Inactivation Dose: A Useful Concept for Intercomparison of Human Cell Survival Curves

1984 • 294 citations

In Vitro Studies of Taxol as a Radiation Sensitizer in Human Tumor Cells

1994 • 268 citations

Drug and radiation resistance in spheroids: cell contact and kinetics

1994 • 268 citations

Taxol sensitizes human astrocytoma cells to radiation.

1992 • 267 citations

The dose-rate effect in human tumour cells

1987 • 266 citations

Selective chemotherapy of noncycling cells in an in vitro tumor model.

1974 • 170 citations

Role of reoxygenation in induction of enhancement of tumor radioresponse by paclitaxel.

1995 • 143 citations

Comparative in vitro cytotoxicity of taxol and Taxotere against cisplatin-sensitive and-resistant human ovarian carcinoma cell lines

1992 • 138 citations

Enhancement of tumor radioresponse of a murine mammary carcinoma by paclitaxel.

1994 • 127 citations

Three-dimensional histoculture: origins and applications in cancer research.

1991 • 118 citations

The radiobiology of human neuroblastoma

1985 • 94 citations

Taxol Sensitizes Human Ovarian Cancer Cells to Radiation

1993 • 93 citations

The Inactivation of Chinese Hamster Cells by X Rays: Synchronized and Exponential Cell Populations

1975 • 91 citations

Distribution and Activity of Antineoplastic Drugs in a Tumor Model

1989 • 86 citations

Changes in radiation survival curve parameters in human tumor and rodent cells exposed to paclitaxel (taxol®)

1994 • 84 citations

Relations between the penetration, binding and average concentration of cytostatic drugs in human tumour spheroids

1992 • 72 citations

An overview of experience with taxol∗ (paclitaxel) in the U.S.A

1993 • 70 citations

DNA Organization Affects Cellular Radiosensitivity and Detection of Initial DNA Strand Breaks

1992 • 68 citations

Radiation and taxol effects on synchronized human cervical carcinoma cells

1994 • 64 citations

Lack of radiosensitization after paclitaxel treatment of three human carcinoma cell lines

1995 • 50 citations

Relationship between Surviving Fractions Using the Colony Method, the LD 50 , and the Growth Delay after Irradiation of Human Melanoma Cells Grown as Multicellular Spheroids

1981 • 40 citations

Radiation response of multicellular spheroids initiated from five human melanoma xenograft lines. Relationship to the radioresponsivenessin vivo

1986 • 34 citations

Multicellular tumor spheroids in radiotherapy research (review).

1990 • 30 citations

Concepts of synergism and antagonism.

1994 • 24 citations

Radiosensitivity of multicellular tumour spheroids obtained from human ovarian cancers

1995 • 24 citations

Heterogeneity in the fractionation sensitivities of human tumor cell lines: Studies in a three-dimensional model system

1995 • 24 citations

Old drugs revisited, new drugs, and experimental approaches in ovarian cancer therapy.

1991 • 22 citations

Radiosensitivity of different human tumor cell lines grown as multicellular spheroids determined from growth curves and survival data

1989 • 18 citations

Response of human neuroblastoma and melanoma multicellular tumor spheroids (MTS) to single dose irradiation

1986 • 14 citations

Effects of 5-fluorouracil and leucovorin in spheroids: a model for solid tumours.

1991 • 12 citations

Spheroid control of malignant glioma cell lines after fractionated irradiation: relation to the surviving fractions at 2 Gy and colony forming efficiencies in a soft agar clonogenic assay

1993 • 10 citations