Thymidylate synthetase purified to homogeneity from human leukemic cells.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Determination of protein: A modification of the lowry method that gives a linear photometric response

1972 • 5,490 citations

Assay of proteins in the presence of interfering materials

1976 • 3,217 citations

Continuous culture of human lymphoblasts from peripheral blood of a child with acute leukemia

1965 • 1,213 citations

Complete amino acid analysis of proteins from a single hydrolysate.

1976 • 986 citations

Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate

1974 • 619 citations

Thymidylate synthetase - a target enzyme in cancer chemotherapy

1977 • 514 citations

Antineoplastic and Immunosuppressive Agents

1975 • 236 citations

Thymidylate synthetase from amethopterin- resistant Lactobacillus casei

1971 • 228 citations

Direct Spectrophotometric Evidence for the Oxidation of Tetrahydrofolate during the Enzymatic Synthesis of Thymidylate

1961 • 209 citations

Thymidylate synthetase: Mechanism of inhibition by 5-fluoro-2′-deoxyuridylate

1972 • 197 citations

Effect of 5,10-methylenetetrahydrofolate on the dissociation of 5-fluoro-2'-deoxyuridylate from thymidylate synthetase: evidence for an ordered mechanism

1978 • 175 citations

Fluorinated pyrimidines. Structures of reversible and irreversible complexes of thymidylate synthetase and fluorinated pyrimidine nucleotides

1974 • 172 citations

5-Fluoro-2′-Deoxyuridylate: Covalent Complex with Thymidylate Synthetase

1972 • 168 citations

[3] Covalent linkage of functional groups, ligands, and proteins to polyacrylamide beads

1974 • 97 citations

Filter assay for thymidylate synthetase using 5-fluoro-2'-deoxyuridylate as an active site titrant

1974 • 80 citations

Human thymidylate synthetase derived from blast cells of patients with acture myelocytic leukemia. Purification and chracterization.

1977 • 79 citations

Microassay of protein with nitrocellulose membrane filters

1968 • 51 citations

Sulfhydryl group modification of thymidylate synthetase and its effect on activity and ternary complex formation.

1977 • 45 citations

Amino acid sequence at the FdUMP binding site of thymidylate synthetase.

1976 • 43 citations

THYMIDYLATE SYNTHETASE AND ITS RELATIONSHIP TO DIHYDROFOLATE REDUCTASE*

1971 • 39 citations

Purification and properties of T2 bacteriophage-induced thymidylate synthetase

1974 • 39 citations

The effect of raney nickel on the covalent thymidylate synthetase-5-fluoro-2'-deoxyuridylate-5,10-methylenetetrahydrofolate complex

1976 • 31 citations

Bacteriophage-coded thymidylate synthetase: Characteristics of the T4 and T5 enzymes

1973 • 29 citations

Purification and properties of thymidylate synthase from calf thymus

1972 • 27 citations

Purification of thymidylate synthetase from enzyme-poor sources by affinity chromatography

1976 • 25 citations

Effect of methotrexate on thymidylate synthetase in cultured parenchymal cells isolated from regenerating rat liver.

1975 • 23 citations

Studies on the reactivity of the essential cysteine of thymidylate synthetase

1977 • 20 citations

Essential arginyl residues in thymidylate synthetase

1978 • 12 citations