Questioning the Th1/Th2 Paradigm in Reproduction: Peripheral Levels of IL‐12 are Down‐Regulated in Miscarriage Patients

Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon?

1993 • 2,828 citations

Th 1-type immunity is incompatible with successful pregnancy

1997 • 1,008 citations

Synthesis of T helper 2-type cytokines at the maternal-fetal interface.

1993 • 911 citations

Some immunological and endocrinological problems raised by the evolution of viviparity in verte- brates

1953 • 838 citations

The neutrophil as a cellular source of chemokines

2000 • 775 citations

Defective production of both leukemia inhibitory factor and type 2 T-helper cytokines by decidual T cells in unexplained recurrent abortions

1998 • 670 citations

Control of fetal survival in CBA x DBA/2 mice by lymphokine therapy

1990 • 504 citations

IL-10 prevents naturally occurring fetal loss in the CBA x DBA/2 mating combination, and local defect in IL-10 production in this abortion-prone combination is corrected by in vivo injection of IFN-τ

2005 • 463 citations

IL-10 prevents naturally occurring fetal loss in the CBA x DBA/2 mating combination, and local defect in IL-10 production in this abortion-prone combination is corrected by in vivo injection of IFN-tau.

1995 • 395 citations

T helper 1 response against Leishmania major in pregnant C57BL/6 mice increases implantation failure and fetal resorptions. Correlation with increased IFN-gamma and TNF and reduced IL-10 production by placental cells.

1996 • 345 citations

Maternal Th1- and Th2-Type Reactivity to Placental Antigens in Normal Human Pregnancy and Unexplained Recurrent Spontaneous Abortions

1999 • 331 citations

Immunoregulation by interleukin-12

1996 • 298 citations

A brief review of recent data on some cytokine expressions at the materno-foetal interface which might challenge the classical Th1/Th2 dichotomy

2002 • 270 citations

Why Did Your Mother Reject You? Immunogenetic Determinants of the Response to Environmental Selective Pressure Expressed at the Uterine Level

1999 • 198 citations

IL-12–induced IFN-γ is dependent on caspase-1 processing of the IL-18 precursor

1999 • 195 citations

Functions of uterine natural killer cells are mediated by interferon gamma production during murine pregnancy

2001 • 180 citations

IFN-gamma is produced by polymorphonuclear neutrophils in human uterine endometrium and by cultured peripheral blood polymorphonuclear neutrophils.

1998 • 141 citations

The Th2 cytokines IL-4 and IL-10 are not crucial for the completion of allogeneic pregnancy in mice

2001 • 134 citations

IFN-γ Is Produced by Polymorphonuclear Neutrophils in Human Uterine Endometrium and by Cultured Peripheral Blood Polymorphonuclear Neutrophils

1998 • 107 citations

Cytokine Production by Lymphocytes in Pregnancy

1997 • 96 citations

Soluble Receptors Neutralizing TNF‐α and IL‐1 Block Stress‐Triggered Murine Abortion

1997 • 92 citations

Murine T Cell Determination of Pregnancy Outcome

1999 • 88 citations

IgG asymmetric molecules with antipaternal activity isolated from sera and placenta of pregnant human

1991 • 78 citations

Murine Stress‐triggered Abortion is Mediated by Increase of CD8⁺ TNF‐α⁺ Decidual Cells via Substance P

2001 • 69 citations

A Progesterone-Induced Protein Increases the Synthesis of Asymmetric Antibodies

1996 • 68 citations

Synthesis and granular localization of tumor necrosis factor-alpha in activated NK cells in the pregnant mouse uterus

1995 • 50 citations

Altered interleukin 12 and nitric oxide levels in recurrrent miscarriage

1997 • 46 citations

During Pregnancy, in the Context of a Th2‐Type Cytokine Profile, Serum IL‐6 Levels Might Condition the Quality of the Synthesized Antibodies

2001 • 42 citations

In vitro susceptibility of mouse placental trophoblast to cytotoxic effector cells

1983 • 40 citations

Expression of the interferon-γ receptor gene in mouse placentas is related to stage of gestation and is restricted to specific subpopulations of trophoblast cells

1994 • 34 citations

Expression of maternal and paternal antigens on trophoblast

1976 • 32 citations

Current topic: Interferon and human placental development

1990 • 22 citations

Immunosuppressive Properties of Monoclonal Antibodies and Human Polyclonal Alloantibodies to the R80K Protein of Trophoblast

1996 • 21 citations

An 80‐kDa Syncytiotrophoblast Alloantigen Bound to Maternal Alloantibody in Term Placenta

1995 • 21 citations

Circulating Interferon-γ- and Interleukin-4-Secreting Cells in Recurrent Spontaneous Abortions

1999 • 18 citations

Interferon-?? Production by T Lymphocytes from Renal Cell Carcinoma Patients: Evidence of Impaired Secretion in Response to Interleukin-12

1999 • 16 citations

Durchflußzytometrie in der klinischen Zelldiagnostik. Herausgegeben von G. Schmitz und G. Rothe: 559 Seiten. 143 Abb. und 61 Tab. Schattauer Verlagsgesellschaft, Stuttgart, New York 1994. Preis: 98.– DM

1995 • 10 citations