Defective production of both leukemia inhibitory factor and type 2 T-helper cytokines by decidual T cells in unexplained recurrent abortions

Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon?

1993 • 2,828 citations

Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor

1992 • 2,004 citations

Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells.

1993 • 1,704 citations

Synthesis of T helper 2-type cytokines at the maternal-fetal interface.

1993 • 911 citations

Progesterone favors the development of human T helper cells producing Th2-type cytokines and promotes both IL-4 production and membrane CD30 expression in established Th1 cell clones.

1995 • 731 citations

Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones.

1992 • 697 citations

Uterine expression of leukemia inhibitory factor coincides with the onset of blastocyst implantation.

1991 • 507 citations

Control of fetal survival in CBA x DBA/2 mice by lymphokine therapy

1990 • 504 citations

T-Helper 1-Type Immunity to Trophoblast in Women With Recurrent Spontaneous Abortion

1995 • 495 citations

IL-10 prevents naturally occurring fetal loss in the CBA x DBA/2 mating combination, and local defect in IL-10 production in this abortion-prone combination is corrected by in vivo injection of IFN-τ

2005 • 463 citations

IL-10 prevents naturally occurring fetal loss in the CBA x DBA/2 mating combination, and local defect in IL-10 production in this abortion-prone combination is corrected by in vivo injection of IFN-tau.

1995 • 395 citations

A progesterone-dependent immunomodulatory protein alters the Th1Th2 balance

1996 • 347 citations

T helper 1 response against Leishmania major in pregnant C57BL/6 mice increases implantation failure and fetal resorptions. Correlation with increased IFN-gamma and TNF and reduced IL-10 production by placental cells.

1996 • 345 citations

Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigen-specific IFN-gamma response and increased production of T helper 2 cytokines.

1996 • 311 citations

Leukaemia inhibitory factor mRNA concentration peaks in human endometrium at the time of implantation and the blastocyst contains mRNA for the receptor at this time

1994 • 294 citations

The production of leukaemia inhibitory factor by human endometrium: presence in uterine flushings and production by cells in culture

1997 • 284 citations

Cytokines and the Th1/Th2 paradigm in transplantation

1994 • 243 citations

Modulation of leukemia inhibitory factor gene expression and protein biosynthesis in human endometrium.

1995 • 236 citations

Screening for cytokine messenger ribonucleic acids in purified human decidual lymphocyte populations by the reverse-transcriptase polymerase chain reaction.

1994 • 207 citations

The role of pregnancy in the course and aetiology of rheumatoid arthritis

1992 • 172 citations

The Effects of Soluble Products of Activated Lymphocytes and Macrophages on Blastocyst Implantation Events in Vitro1

1991 • 162 citations

Regulation of fetal allograft survival by hormone-controlled Th1- and Th2-type cytokines

1996 • 151 citations

Effects of products of activated leukocytes (lymphokines and monokines) on the growth of malignant trophoblast cells in vitro

1988 • 123 citations

Molecular aspects of implantation: In-vitro endometrial secretion of human interleukin for DA cells/ leukaemia inhibitory factor by explant cultures from fertile and infertile women

1995 • 115 citations

Leukaemia inhibitory factor in human endometrium throughout the menstrual cycle

1996 • 113 citations

Trophic effects of myeloid leukaemia inhibitory factor (LIF) on mouse embryos

1995 • 89 citations

Characterization of cytokine production by the metrial gland and granulated metrial gland cells

1991 • 89 citations

Screening for cytokine mRNA in human villous and extravillous trophoblasts using the reverse-transcriptase polymerase chain reaction (RT-PCR)

1995 • 81 citations

Abnormal production of T helper 2 cytokines interleukin‐4 and interleukin‐5 by T cells from newborns with atopic parents

1996 • 76 citations

Molecular interactions during pregnancy: Expression of leukaemia inhibitory factor (LIF) receptor in human placenta: a possible role for LIF in the growth and differentiation of trophoblasts

1995 • 68 citations

Immunobiology and immunopharmacology of organ allograft rejection

1995 • 44 citations

Immunological tolerance of the fetal allograft: Efficacy of immunotherapy and IL-4 and TNFα serum levels in recurrent abortion

1997 • 10 citations

Biotinylated anti-progesterone monoclonal antibodies specifically target the uterine epithelium and block implantation in the mouse

1992 • 6 citations