Nuclear transport in 3T3 fibroblasts: effects of growth factors, transformation, and cell shape.

Role of cell shape in growth control

1978 • 2,434 citations

PROTEIN-TYROSINE KINASES

1985 • 2,198 citations

Early Signals in the Mitogenic Response

1986 • 1,498 citations

Autocrine growth factors and cancer

1985 • 1,462 citations

125I-labeled human epidermal growth factor. Binding, internalization, and degradation in human fibroblasts.

1976 • 1,293 citations

Sequence requirements for nuclear location of simian virus 40 large-T antigen

1984 • 1,278 citations

RECEPTORS AND PHOSPHOINOSITIDE-GENERATED SECOND MESSENGERS

1985 • 722 citations

Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431.

1978 • 578 citations

Epidermal growth factor stimulates phosphorylation in membrane preparations in vitro

1978 • 448 citations

POLYPEPTIDE GROWTH FACTORS

1984 • 381 citations

A Fluorescence Photobleaching Assay of Gap Junction-mediated Communication Between Human Cells

1986 • 337 citations

The Biology and Mechanism of Action of Nerve Growth Factor

1982 • 324 citations

A method for incorporating macromolecules into adherent cells.

1984 • 307 citations

Variants of 3T3 cells lacking mitogenic response to epidermal growth factor.

1977 • 280 citations

Chromatin binding of epidermal growth factor, nerve growth factor, and platelet-derived growth factor in cells bearing the appropriate surface receptors.

1986 • 193 citations

Molecular mobility and nucleocytoplasmic flux in hepatoma cells.

1986 • 193 citations

Nerve growth factor in the nucleus: interaction with receptors on the nuclear membrane.

1979 • 191 citations

The fate of insulin bound to adipocytes. Evidence for compartmentalization and processing.

1978 • 189 citations

Purification and characterization of epidermal growth factor receptor/protein kinase from normal mouse liver.

1982 • 183 citations

Binding of insulin to isolated nuclei.

1976 • 146 citations

The nuclear envelope. The major site of insulin binding in rat liver nuclei.

1978 • 112 citations

Nuclear accumulation of epidermal growth factor in cultured rat pituitary cells

1980 • 93 citations

Nuclear accumulation of epidermal growth factor in cultured bovine corneal endothelial and granulosa cells.

1981 • 81 citations

Ultrastructural evidence for the accumulation of insulin in nuclei of intact 3T3-L1 adipocytes by an insulin-receptor mediated process.

1987 • 80 citations

Perinuclear location and recycling of epidermal growth factor receptor kinase: immunofluorescent visualization using antibodies directed to kinase and extracellular domains.

1986 • 78 citations

Intracellular distribution of nerve growth factor in rat pheochromocytoma PC12 cells: evidence for a perinuclear and intranuclear location.

1980 • 60 citations

Insulin regulation of protein phosphorylation in isolated rat liver nuclear envelopes: potential relationship to mRNA metabolism.

1983 • 60 citations

Insulin-modulated transport of RNA from isolated liver nuclei

1981 • 52 citations

Biosynthesis and Mechanism of Action of Nerve Growth Factor

1981 • 51 citations

Epidermal growth factor and insulin stimulate nuclear pore-mediated macromolecular transport in isolated rat liver nuclei

1987 • 38 citations

Chemical factors that influence nucleocytoplasmic transport: a fluorescence photobleaching study.

1986 • 37 citations

Insulin binding to isolated liver nuclei from obese and lean mice

1979 • 34 citations

Epidermal growth factor-nonresponsive 3T3 variants do not contain epidermal growth factor receptor-related antigens or mRNA.

1986 • 32 citations

Fluorescence photobleaching assay of tumor promoter 12-O-tetradecanoylphorbol 13-acetate inyibition of cell-cell communication

1987 • 16 citations

Fluorescence redistribution after photobleaching as a tool for dissecting the control elements of nucleocytoplasmic transport

1987 • 9 citations