Anti-PD-1 Blockade and Stereotactic Radiation Produce Long-Term Survival in Mice With Intracranial Gliomas

Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

2005 • 18,835 citations

Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

2010 • 2,721 citations

Fractionated but Not Single-Dose Radiotherapy Induces an Immune-Mediated Abscopal Effect when Combined with Anti–CTLA-4 Antibody

2009 • 1,480 citations

Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma

2006 • 1,254 citations

Blockade of B7-H1 and PD-1 by Monoclonal Antibodies Potentiates Cancer Therapeutic Immunity

2005 • 972 citations

Immune-Mediated Inhibition of Metastases after Treatment with Local Radiation and CTLA-4 Blockade in a Mouse Model of Breast Cancer

2005 • 940 citations

Immunosuppression in Patients with High-Grade Gliomas Treated with Radiation and Temozolomide

2011 • 492 citations

Phase I/II Study of Ipilimumab for Patients With Metastatic Melanoma

2008 • 446 citations

Gene Expression Profile Correlates with T-Cell Infiltration and Relative Survival in Glioblastoma Patients Vaccinated with Dendritic Cell Immunotherapy

2010 • 414 citations

High-Resolution, Small Animal Radiation Research Platform With X-Ray Tomographic Guidance Capabilities

2008 • 340 citations

Systemic CTLA-4 Blockade Ameliorates Glioma-Induced Changes to the CD4+ T Cell Compartment without Affecting Regulatory T-Cell Function

2007 • 320 citations

Potent Induction of Tumor Immunity by Combining Tumor Cryoablation with Anti–CTLA-4 Therapy

2011 • 258 citations

CTLA-4 blockade with ipilimumab induces significant clinical benefit in a female with melanoma metastases to the CNS

2008 • 164 citations

The Combination of Ionizing Radiation and Peripheral Vaccination Produces Long-term Survival of Mice Bearing Established Invasive GL261 Gliomas

2006 • 159 citations

The effect of irradiation on expression of HLA class I antigens in human brain tumors in culture

1994 • 56 citations

Gamma knife surgery for glioblastoma multiforme

2006 • 45 citations

IL-2/Anti-IL-2 Antibody Complex Enhances Vaccine-Mediated Antigen-Specific CD8+ T Cell Responses and Increases the Ratio of Effector/Memory CD8+ T Cells to Regulatory T Cells

2008 • 35 citations

A safety and efficacy study of local delivery of interleukin-12 transgene by PPC polymer in a model of experimental glioma

2008 • 32 citations

Immune Regulatory Antibodies

2010 • 29 citations

Cure of established GL261 mouse gliomas after combined immunotherapy with GM‐CSF and IFNγ is mediated by both CD8⁺ and CD4⁺ T‐cells

2008 • 28 citations