Enrichment and detection of live antigen-specific CD4+ and CD8+ T cells based on cytokine secretion

Phenotypic Analysis of Antigen-Specific T Lymphocytes

1996 • 3,611 citations

Counting Antigen-Specific CD8 T Cells: A Reevaluation of Bystander Activation during Viral Infection

1998 • 1,996 citations

Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA

1998 • 1,426 citations

Phenotypic and Functional Separation of Memory and Effector Human CD8+ T Cells

1997 • 1,391 citations

Induction and Exhaustion of Lymphocytic Choriomeningitis Virus–specific Cytotoxic T Lymphocytes Visualized Using Soluble Tetrameric Major Histocompatibility Complex Class I–Peptide Complexes

1998 • 733 citations

Virus-Specific CD8+ T Cells in Primary and Secondary Influenza Pneumonia

1998 • 685 citations

Rapid Effector Function in CD8+ Memory T Cells

1997 • 652 citations

Determination of antigen-specific memory/effector CD4+ T cell frequencies by flow cytometry: evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency.

1997 • 560 citations

Analysis and sorting of live cells according to secreted molecules, relocated to a cell-surface affinity matrix.

1995 • 305 citations

T-cell epitope mapping by flow cytometry

1998 • 295 citations

Human HLA-A0201-restricted cytotoxic T lymphocyte recognition of influenza A is dominated by T cells bearing the V beta 17 gene segment.

1995 • 268 citations

Direct isolation, phenotyping and cloning of low-frequency antigen-specific cytotoxic T lymphocytes from peripheral blood

1998 • 234 citations

Production of lymphokine mRNA by CD45R+ and CD45R- helper T cells from human peripheral blood and by human CD4+ T cell clones.

1989 • 169 citations

Prospects for adoptive T cell therapy

1997 • 139 citations

Sequential production of IL-2, IFN-γ and IL-10 by individual staphylococcal enterotoxin B-activated T helper lymphocytes

1998 • 106 citations

Number of interleukin‐4‐ and interferon‐γ‐secreting human T cells reactive with tetanus toxoid and the mycobacterial antigen PPD or phytohemagglutinin: distinct response profiles depending on the type of antigen used for activation

1993 • 97 citations

Analyzing cytotoxic T lymphocyte activity: a simple and reliable flow cytometry-based assay

1997 • 60 citations

Biomagnetic isolation of antigen-specific CD8+ T cells usable in immunotherapy

1998 • 49 citations

Detection of Hybridomas Secreting Monoclonal Antibodies to Human Gamma Interferon Using a Rapid Screening Technique and Specificity of Certain Monoclonal Antibodies to Gamma Interferon

1984 • 34 citations

Chemiluminescent and Enzyme-Linked Immuno Assays for Sensitive Detection of Human IFN-γ

1994 • 30 citations

Development of immunoassays for human interleukin 3 and interleukin 4, some of which discriminate between different recombinant DNA-derived molecules

1991 • 21 citations