Chemiluminescent and Enzyme-Linked Immuno Assays for Sensitive Detection of Human IFN-γ

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

Antibodies to major histocompatibility antigens produced by hybrid cell lines

1977 • 1,727 citations

Measurements of the true affinity constant in solution of antigen-antibody complexes by enzyme-linked immunosorbent assay

1985 • 1,241 citations

Induction of TH1 and TH2 responses: a key role for the ‘natural’ immune response?

1992 • 794 citations

IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses.

1988 • 731 citations

Impaired Production of Lymphokines and Immune (Gamma) Interferon in the Acquired Immunodeficiency Syndrome

1984 • 513 citations

Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma

1988 • 476 citations

The role of IFN-gamma in delayed-type hypersensitivity mediated by Th1 clones.

1989 • 304 citations

Monoclonal antibodies: Purification, fragmentation and application to structural and functional studies of class I MHC antigens

1982 • 283 citations

Chemiluminescence immunoassay: an overview

1986 • 208 citations

Interferon gamma induces the expression of human immunodeficiency virus in persistently infected promonocytic cells (U1) and redirects the production of virions to intracytoplasmic vacuoles in phorbol myristate acetate-differentiated U1 cells.

1992 • 148 citations

Evidence that defective interferon-gamma production in dermatitis patients is due to intrinsic abnormalities

1990 • 137 citations

Use of monoclonal antibodies as sensitive and specific probes for biologically active human gamma-interferon.

1984 • 130 citations

Monoclonal antibodies to human immune interferon and their use in a sensitive solid-phase ELISA

1985 • 117 citations

Interferon-γ: Producer cells, activation stimuli, and molecular genetic regulation

1990 • 110 citations

Heterogeneous effects of IFN-gamma in adjuvant arthritis.

1989 • 109 citations

Anti-interferon gamma treatment blocks the ability of glutaraldehyde-polymerized allergens to inhibit specific IgE responses.

1991 • 89 citations

Biological Activities and Receptor Binding of Two Human Recombinant Interferons and their Hybrids

1986 • 83 citations

Monoclonal antibody two-site ELISA for human IFN-γ

1989 • 79 citations

Interferon γ: a master key in the immune system

1988 • 72 citations

A simple, rapid and large capacity ELISA for biologically active native and recombinant human IFN gamma.

1987 • 68 citations

CD4+ T-cell subsets: regulation of differentiation and function

1991 • 67 citations

Production of human immune interferon (Hu IFN‐γ) studied at the single cell level. Origin, evidence for spontaneous secretion and effect of cyclosporin A

1983 • 49 citations

Novel poly‐substituted aryl acridinium esters and their use in immunoassay

1989 • 48 citations

Cytokines and anti-cytokines

1989 • 38 citations

Suppression and augmentation of rat adjuvant arthritis with monoclonal anti-interferon-gamma antibody.

1989 • 36 citations

An immunofluorescent method for identifying individual IFN-γ-producing lymphocytes

1986 • 27 citations

HIV-1-specific production of IFN-gamma and modulation by recombinant IL-2 during early HIV-1 infection.

1988 • 26 citations

Cloning and Expression of a Novel Variant of Human Interferon-γ cDNA

1985 • 25 citations

Interferon-γ Marks Activated T Lymphocytes in AIDS Patients

1990 • 18 citations

Phenotypic characterization of individual interferon‐γ‐producing cells after OKT3 antibody activation

1986 • 14 citations

Generation of a New Monoclonal Antibody and Its Application for Determination and Purification of Biologically Active Human Gamma-Interferon

1986 • 12 citations

Characterization of Murine Monoclonal Antibodies to Human Interferon‐Gamma (IFN‐γ) and Their Application for Sandwich Enzyme‐Linked Immunosorbent Assay (ELISA)

1987 • 12 citations

A competitive inhibition ELISA for the quantification of human interferon-γ

1993 • 11 citations

HuIFN-γ Antiviral Activity Correlates with Immunological Reactivity in a Double-Monoclonal Antibody Radiometrie Assay

1985 • 9 citations

CHARACTERIZATION OF MONOCLONAL ANTIBODIES TO HUMAN INTERFERON-GAMMA AND THEIR APPLICATION TO ENZYME-LINKED IMMUNOSORBENT ASSAY (ELISA)

1989 • 2 citations

Production and Measurement of Interferons

1988 • 1 citations