Actin Polymerization, Calcium-Transients, and Phospholipid Metabolism in Human Neutrophils After Stimulation with Interleukin-8 and N-formyl Peptide

Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils.

1989 • 1,993 citations

Signaling through phosphatidylcholine breakdown.

1990 • 1,362 citations

Structure and Functional Expression of a Human Interleukin-8 Receptor

1991 • 1,088 citations

Cloning of Complementary DNA Encoding a Functional Human Interleukin-8 Receptor

1991 • 878 citations

Purification and partial biochemical characterization of a human monocyte-derived, neutrophil-activating peptide that lacks interleukin 1 activity.

1987 • 542 citations

From signal to pseudopod

1989 • 460 citations

Phosphatidylcholine Hydrolysis by Phospholipase D Determines Phosphatidate and Diglyceride Levels in Chemotactic Peptide-stimulated Human Neutrophils

1989 • 429 citations

Production of interleukin-8 by human dermal fibroblasts and keratinocytes in response to interleukin-1 or tumour necrosis factor.

1989 • 422 citations

Signal transduction and cytoskeletal activation in the neutrophil.

1987 • 282 citations

Marked synergism between tumor necrosis factor-alpha and interferon-gamma in regulation of keratinocyte-derived adhesion molecules and chemotactic factors.

1990 • 261 citations

Transient increase in phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol trisphosphate during activation of human neutrophils

1989 • 256 citations

Two distinct Gi-proteins mediate formyl peptide receptor signal transduction in human leukemia (HL-60) cells

1989 • 183 citations

The dynamics of ligand-receptor interactions. Real-time analyses of association, dissociation, and internalization of an N-formyl peptide and its receptors on the human neutrophil.

1984 • 178 citations

Upper Keratinocytes of Psoriatic Skin Lesions Express High Levels of NAP-1/IL-8 mRNA In Situ

1991 • 175 citations

Phosphatidic acid as a second messenger in human polymorphonuclear leukocytes. Effects on activation of NADPH oxidase.

1991 • 165 citations

Localization of Neutrophil-Activating Peptide-1/Interleukin-8-Immunoreactivity in Normal and Psoriatic Skin

1991 • 162 citations

Is there a relationship between phosphatidylinositol trisphosphate and F-actin polymerization in human neutrophils?

1990 • 153 citations

Neutrophil-Activating Proteins in Psoriasis

1992 • 141 citations

Characterization of a receptor for human monocyte-derived neutrophil chemotactic factor/interleukin-8.

1990 • 131 citations

Signal transduction and ligand-receptor dynamics in the human neutrophil. Transient responses and occupancy-response relations at the formyl peptide receptor.

1985 • 120 citations

Diacylglycerol accumulation and superoxide anion production in stimulated human neutrophils.

1987 • 103 citations

Interleukin-8 Immunoreactivity in the Skin of Healthy Subjects and Patients with Palmoplantar Pustulosis and Psoriasis

1992 • 101 citations

Regulation of ligand-receptor dynamics by guanine nucleotides. Real-time analysis of interconverting states for the neutrophil formyl peptide receptor.

1987 • 89 citations

Interleukin-8 induces changes in human neutrophil actin conformation and distribution: relationship to inhibition of adhesion to cytokine-activated endothelium

1992 • 83 citations

Signal transduction and ligand-receptor dynamics in the neutrophil. Ca2+ modulation and restoration.

1985 • 76 citations

G-protein activation by interleukin 8 and related cytokines in human neutrophil plasma membranes

1992 • 72 citations

Kinetics of N-formyl peptide receptor up-regulation during stimulation in human neutrophils.

1991 • 52 citations

Chemotactic cytokines in the epidermis

1992 • 51 citations

Postreceptor events associated with human neutrophil activation by interleukin-8

1992 • 50 citations

Normal human epidermal keratinocyte-derived neutrophil chemotactic factor.

1990 • 18 citations

IL-8 stimulates phosphatidylinositol-4-phosphate kinase in human polymorphonuclear leukocytes.

1992 • 15 citations