Disappearance of AML1 ‐MTG8(ETO) fusion transcript in acute myeloid leukaemia patients with t(8;21) in long‐term remission

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Nonparametric Estimation from Incomplete Observations

1958 • 37,219 citations

Proposed Revised Criteria for the Classification of Acute Myeloid Leukemia

1985 • 2,981 citations

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.

1991 • 897 citations

The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.

1993 • 523 citations

Persistence of the 8;21 translocation in patients with acute myeloid leukemia type M2 in long-term remission

1993 • 297 citations

Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for the PML/RAR-alpha fusion mRNA

1993 • 223 citations

An AML1/ETO fusion transcript is consistently detected by RNA-based polymerase chain reaction in acute myelogenous leukemia containing the (8;21)(q22;q22) translocation

1993 • 174 citations

AML1/ETO fusion mRNA can be detected in remission blood samples of all patients with t(8;21) acute myeloid leukemia after chemotherapy or autologous bone marrow transplantation.

1994 • 156 citations

Prognostic significance of Philadelphia chromosome-positive cells detected by the polymerase chain reaction after allogeneic bone marrow transplant for chronic myelogenous leukemia

1992 • 145 citations

Junctions of the AML1/MTG8(ETO) fusion are constant in t(8;21) acute myeloid leukemia detected by reverse transcription polymerase chain reaction

1993 • 139 citations

Detection of the chromosome 16 CBF beta-MYH11 fusion transcript in myelomonocytic leukemias

1995 • 114 citations

Detection of Philadelphia chromosome-positive acute lymphoblastic leukemia by polymerase chain reaction: possible eradication of minimal residual disease by marrow transplantation

1992 • 113 citations

Clinical significance of bcr-abl gene rearrangement detected by polymerase chain reaction after allogeneic bone marrow transplantation in chronic myelogenous leukemia

1991 • 106 citations

The use of the polymerase chain reaction for the detection of minimal residual malignant disease [editorial]

1991 • 91 citations

Quantitative PCR techniques and applications.

1995 • 90 citations

HUMAN GENE MAPPING: A COMPENDIUM

1994 • 87 citations

Detection of minimal residual disease in acute myelomonocytic leukemia with abnormal marrow eosinophils by nested polymerase chain reaction with allele specific amplification

1994 • 84 citations

Expression of AML1-ETO fusion transcripts and detection of minimal residual disease in t(8;21)-positive acute myeloid leukemia.

1993 • 83 citations

Annotation

1995 • 77 citations

The 8;21 chromosome translocation in acute myeloid leukemia is always detectable by molecular analysis using AML1

1993 • 71 citations

Use of the polymerase chain reaction in the detection of AML1/ETO fusion transcript in t(8;21)

1995 • 51 citations

Detection of AML1/ETO fusion transcript as a tool for diagnosing t(8;21) positive acute myelogenous leukemia.

1994 • 50 citations

Detection of t(8;21) by reverse transcriptase polymerase chain reaction in patients in remission of acute myeloid leukaemia type M2 after chemotherapy or bone marrow transplantation

1994 • 48 citations

Further characterization of acute myelogenous leukemia with t(8; 21) chromosome translocation

1982 • 40 citations

Translocation breakpoints are clustered on both chromosome 8 and chromosome 21 in the t(8;21) of acute myeloid leukemia

1993 • 35 citations

Alternative, out-of-frame runt/MTG8 transcripts are encoded by the derivative (8) chromosome in the t(8;21) of acute myeloid leukemia M2

1994 • 30 citations

Molecular diversity in AML1/ETO fusion transcripts in patients with t(8;21) positive acute myeloid leukaemia.

1994 • 20 citations