Dendritic cell vaccination for cancer therapy

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

1994 • 5,204 citations

Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells

1998 • 2,916 citations

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

1993 • 2,828 citations

The Nature of the Principal Type 1 Interferon-Producing Cells in Human Blood

1999 • 2,255 citations

Proliferating dendritic cell progenitors in human blood.

1994 • 1,922 citations

Reciprocal Control of T Helper Cell and Dendritic Cell Differentiation

1999 • 1,912 citations

Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells

1996 • 1,908 citations

Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells

1996 • 1,854 citations

Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon

1999 • 1,754 citations

GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells

1992 • 1,608 citations

Vaccination with Mage-3a1 Peptide–Pulsed Mature, Monocyte-Derived Dendritic Cells Expands Specific Cytotoxic T Cells and Induces Regression of Some Metastases in Advanced Stage IV Melanoma

1999 • 1,260 citations

The Enigmatic Plasmacytoid T Cells Develop into Dendritic Cells with Interleukin (IL)-3 and CD40-Ligand

1997 • 1,224 citations

Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity

1995 • 1,097 citations

CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha.

1996 • 962 citations

Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines.

1996 • 849 citations

Dendritic Cells in Cancer Immunotherapy

2000 • 698 citations

In Breast Carcinoma Tissue, Immature Dendritic Cells Reside within the Tumor, Whereas Mature Dendritic Cells Are Located in Peritumoral Areas

1999 • 540 citations

Dendritic Cell Vaccines for Cancer Immunotherapy

1999 • 497 citations

Identification of proliferating dendritic cell precursors in mouse blood.

1992 • 445 citations

Processing of Some Antigens by the Standard Proteasome but Not by the Immunoproteasome Results in Poor Presentation by Dendritic Cells

2000 • 418 citations

The distinct surface of human blood dendritic cells, as observed after an improved isolation method.

1990 • 402 citations

Dendritic cells as mediators of tumor-induced tolerance in metastatic melanoma

1997 • 384 citations

Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes.

1995 • 372 citations

Induction of cytotoxic T cell responses and tumor immunity against unrelated tumors using telomerase reverse transcriptase RNA transfected dendritic cells.

2000 • 355 citations

Phase I study in melanoma patients of a vaccine with peptide-pulsed dendritic cells generatedin vitro from CD34+ hematopoietic progenitor cells

2000 • 337 citations

Induction of antigen-specific cytolytic T cells in situ in human melanoma by immunization with synthetic peptide-pulsed autologous antigen presenting cells.

1995 • 324 citations

Induction of tumor immunity and cytotoxic T lymphocyte responses using dendritic cells transfected with messenger RNA amplified from tumor cells.

2000 • 319 citations

A Phase I study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic malignancies expressing carcinoembryonic antigen.

1999 • 299 citations

Granulocyte-macrophage colony-stimulating factor promotes differentiation and survival of human peripheral blood dendritic cells in vitro.

1990 • 269 citations

Infusion of dendritic cells pulsed with HLA-A2-specific prostate-specific membrane antigen peptides: A phase II prostate cancer vaccine trial involving patients with hormone-refractory metastatic disease

1999 • 242 citations

Dendritic Cells Capture Killed Tumor Cells and Present Their Antigens to Elicit Tumor-Specific Immune Responses

2000 • 237 citations

Presence of IgE antibodies to bovine serum albumin in a patient developing anaphylaxis after vaccination with human peptide-pulsed dendritic cells

2000 • 234 citations

Tumor antigen presentation by murine epidermal cells.

1991 • 211 citations

Phase 1 Study in Patients With Metastatic Melanoma of Immunization With Dendritic Cells Presenting Epitopes Derived From the Melanoma-Associated Antigens MART-1 and gp100

2000 • 179 citations

Human sunlight-induced basal-cell-carcinoma-associated dendritic cells are deficient in T cell co-stimulatory molecules and are impaired as antigen-presenting cells.

1997 • 170 citations

Systemic administration of interleukin 2 enhances the therapeutic efficacy of dendritic cell-based tumor vaccines

1999 • 168 citations

Dendritic cell-based immunotherapy of prostate cancer: immune monitoring of a phase II clinical trial.

2000 • 164 citations

Enhancement of cytolytic T lymphocyte precursor frequency in melanoma patients following immunization with the MAGE-1 peptide loaded antigen presenting cell-based vaccine.

1996 • 150 citations

Dendritic Cells in Fundamental and Clinical Immunology

1995 • 108 citations

Monocyte-derived dendritic cells have a phenotype comparable to that of dermal dendritic cells and display ultrastructural granules distinct from Birbeck granules

1998 • 95 citations

Novel methods to monitor antigen-specific cytotoxic T-cell responses in cancer immunotherapy

1998 • 86 citations

Influence of dendritic cells on tumor growth.

1985 • 84 citations

Synergistic Action of fms-Like Tyrosine Kinase 3 Ligand and CD40 Ligand in the Induction of Dendritic Cells and Generation of Antitumor Immunity In Vivo

1999 • 53 citations

Dendritic Cell-Based Vaccines: From Mouse Models to Clinical Cancer Immunotherapy

2000 • 38 citations

Role of Dendritic Cells in Benign and Malignant Lymphocytic Infiltrates of the Skin

1994 • 25 citations

Idiotype Vaccination Using Dendritic Cells After Autologous Peripheral Blood Stem Cell Transplantation for Multiple Myeloma—A Feasibility Study

1999 • 21 citations

Vaccination with Tumor Antigen-Pulsed Dendritic Cells Induces in Vivo Resistance to A B Cell Lymphoma

1993 • 19 citations

Publish and Subscribe Publizistisches Spiel

1993 • 2 citations

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