Investigation of the role of macrophages and endogenous interferon-γ in natural resistance of mice againstLegionella pneumophilainfection

Legionnaires' Disease

1977 • 1,687 citations

The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes.

1983 • 704 citations

Legionnaires' Disease Bacterium (Legionella pneumophila) Multiplies Intracellularly in Human Monocytes

1980 • 648 citations

Interferon-Gamma, the Activated Macrophage, and Host Defense Against Microbial Challenge

1988 • 428 citations

Legionella pneumophila inhibits acidification of its phagosome in human monocytes.

1984 • 384 citations

Interferon gamma-activated human monocytes downregulate transferrin receptors and inhibit the intracellular multiplication of Legionella pneumophila by limiting the availability of iron.

1989 • 332 citations

One-step purification of mouse monoclonal antibodies from ascitic fluid by DEAE Affi-gel blue chromatography

1982 • 322 citations

Early gamma interferon production by natural killer cells is important in defense against murine listeriosis

1991 • 316 citations

Interaction between the legionnaires' disease bacterium (Legionella pneumophila) and human alveolar macrophages. Influence of antibody, lymphokines, and hydrocortisone.

1984 • 252 citations

Regulation of gamma interferon production by natural killer cells in scid mice: roles of tumor necrosis factor and bacterial stimuli

1991 • 215 citations

Relation of capsular materials and colony opacity to virulence of Vibrio vulnificus

1985 • 206 citations

Growth of Legionella pneumophila in thioglycolate-elicited peritoneal macrophages from A/J mice

1988 • 189 citations

Interactions between endogenous gamma interferon and tumor necrosis factor in host resistance against primary and secondary Listeria monocytogenes infections

1989 • 135 citations

IFN-gamma-activated human alveolar macrophages inhibit the intracellular multiplication of Legionella pneumophila.

1988 • 123 citations

Roles of CD4+ and CD8+ cells, and the effect of administration of recombinant murine interferon gamma in listerial infection.

1990 • 68 citations

Purification and Further Characterization of an Anti-Murine Interferon-γ Monoclonal Neutralizing Antibody

1986 • 65 citations

Multiplication of Legionella pneumophila Philadelphia-1 in cultured peritoneal macrophages and its correlation to susceptibility of animals

1986 • 61 citations

Evidence that endogenous gamma interferon is produced early in Listeria monocytogenes infection

1990 • 60 citations

Role of gamma interferon in induction of natural killer activity by Legionella pneumophila in vitro and in an experimental murine infection model

1988 • 46 citations

Interleukin-1-induced promotion of T-cell differentiation in mice immunized with killed Listeria monocytogenes

1990 • 32 citations

Inhibition of polymorphonuclear leukocyte function by Legionella pneumophila exoproducts

1990 • 17 citations

Fate of Legionella pneumophila Philadelphia-1 strain in resident, elicited, activated, and immune peritoneal macrophages of guinea pigs

1987 • 14 citations

Macrophage-activating T-cell factor(s) produced in an early phase of Legionella pneumophila infection in guinea pigs

1989 • 13 citations

Kinetics and characterization of interferon production by murine spleen cells stimulated with Legionella pneumophila antigens

1985 • 13 citations

Case 13512

1927 • 1 citations