Internalization and degradation of hepatocyte growth factor in hepatocytes with down‐regulation of the receptor/c‐Met

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

1991 • 2,230 citations

Molecular cloning and expression of human hepatocyte growth factor

1989 • 2,191 citations

Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

1991 • 1,176 citations

Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor

1989 • 664 citations

Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor.

1991 • 663 citations

Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure.

1988 • 657 citations

High and low affinity binding sites for basic fibroblast growth factor on cultured cells: Absence of a role for low affinity binding in the stimulation of plasminogen activator production by bovine capillary endothelial cells

1987 • 653 citations

Evidence for the identity of human scatter factor and human hepatocyte growth factor.

1991 • 651 citations

Purification and subunit structure of hepatocyte growth factor from rat platelets

1987 • 557 citations

A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor.

1991 • 502 citations

Purification and biological characterization of human hepatopoietin A, a polypeptide growth factor for hepatocytes.

1989 • 455 citations

Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues.

1990 • 333 citations

Hepatocyte growth factor/hepatopoietin A stimulates the growth of rat kidney proximal tubule epithelial cells (RPTE), rat nonparenchymal liver cells, human melanoma cells, mouse keratinocytes and stimulates anchorage-independent growth of SV-40 transformed RPTE

1991 • 253 citations

Interaction of platelet-derived growth factor with its fibroblast receptor. Demonstration of ligand degradation and receptor modulation.

1982 • 239 citations

Internalization of interleukin 2 is mediated by the beta chain of the high-affinity interleukin 2 receptor.

1987 • 234 citations

Activation of hepatocyte growth factor by proteolytic conversion of a single chain form to a heterodimer.

1992 • 211 citations

Basic fibroblast growth factor is internalized through both receptor-mediated and heparan sulfate-mediated mechanisms.

1992 • 198 citations

High-affinity receptor-mediated internalization and degradation of interleukin 2 in human T cells.

1986 • 192 citations

Metabolism of proteoglycans in rat ovarian granulosa cell culture. Multiple intracellular degradative pathways and the effect of chloroquine.

1984 • 164 citations

Internalized insulin receptors are recycled to the cell surface in rat hepatocytes.

1982 • 142 citations

Tumor cytotoxic factor/hepatocyte growth factor from human fibroblasts: Cloning of its cDNA, purification and characterization of recombinant protein

1991 • 139 citations

Primary structure of rat hepatocyte growth factor and induction of its mRNA during liver regeneration following hepatic injury

1990 • 114 citations

Contractile arrest accelerates myosin heavy chain degradation in neonatal rat heart cells

1992 • 93 citations

Turnover of heparan sulfate proteoglycan in human colon carcinoma cells. A quantitative biochemical and autoradiographic study.

1987 • 83 citations

Identification and partial characterization of receptor binding sites for HGF on rat hepatocytes

1990 • 69 citations

Identification of the N-terminal residue of the heavy chain of both native and recombinant human hepatocyte growth factor

1991 • 58 citations

Correlations between heparan sulfate metabolism and hepatoma growth

1989 • 58 citations

Characterization of hepatocyte‐growth‐factor receptors on Meth A cells

1992 • 44 citations

Identification and partial characterization of two classes of receptors for human hepatocyte growth factor on adult rat hepatocytes in primary culture.

1992 • 33 citations