A mutation that prevents GTP-dependent activation of the α chain of Gs

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

G Proteins: A Family of Signal Transducers

1986 • 975 citations

Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium.

1987 • 751 citations

Activation of adenylate cyclase by the diterpene forskolin does not require the guanine nucleotide regulatory protein.

1981 • 735 citations

Structure of the GDP Domain of EF-Tu and Location of the Amino Acids Homologous to ras Oncogene Proteins

1985 • 626 citations

Biological and biochemical properties of human rasH genes mutated at codon 61

1986 • 538 citations

ATP-binding site of adenylate kinase: mechanistic implications of its homology with ras-encoded p21, F1-ATPase, and other nucleotide-binding proteins.

1986 • 538 citations

Three-Dimensional Structure of an Oncogene Protein: Catalytic Domain of Human c-H- ras P21

1988 • 532 citations

Homologies Between Signal Transducing G Proteins and ras Gene Products

1984 • 500 citations

The yeast SCG1 gene: A Gα-like protein implicated in the a- and α-factor response pathway

1987 • 431 citations

Structural details of the binding of guanosine diphosphate to elongation factor Tu from E. coli as studied by X-ray crystallography.

1985 • 396 citations

Fluoride complexes of aluminium or beryllium act on G-proteins as reversibly bound analogues of the gamma phosphate of GTP.

1987 • 383 citations

GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction

1987 • 365 citations

Characterization of transducin from bovine retinal rod outer segments. II. Evidence for distinct binding sites and conformational changes revealed by limited proteolysis with trypsin.

1983 • 331 citations

Identification of receptor contact site involved in receptor–G protein coupling

1987 • 249 citations

A Model for the Tertiary Structure of p21, the Product of the ras Oncogene

1985 • 248 citations

The effect of GTP and Mg2+ on the GTPase activity and the fluorescent properties of Go.

1987 • 231 citations

Family of G protein α chains: amphipathic analysis and predicted structure of functional domains

1986 • 197 citations

The effect of activating ligands on the intrinsic fluorescence of guanine nucleotide-binding regulatory proteins.

1987 • 190 citations

Carboxyl Rerminal Domain of G _sα Specifies Coupling of Receptors to Stimulation of Adenylyl Cyclase

1988 • 174 citations

Construction and Characterization of a Retroviral Vector Demonstrating Efficient Expression of Cloned cDNA Sequences

1988 • 157 citations

Hydrodynamic properties of the regulatory component of adenylate cyclase.

1980 • 81 citations

Identification of the lesion in the stimulatory GTP‐binding protein of the uncoupled S49 lymphoma

1987 • 62 citations