Identification of the lesion in the stimulatory GTP‐binding protein of the uncoupled S49 lymphoma

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

A general method for isolation of high molecular weight DNA from eukaryotes

1976 • 2,827 citations

Ribonucleic acid isolated by cesium chloride centrifugation

1974 • 2,263 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells.

1983 • 933 citations

The making of strand-specific M13 probes

1982 • 652 citations

A comprehensive sequence analysis program for the IBM personal computer

1984 • 605 citations

Human cDNA clones for four species of G alpha s signal transduction protein.

1986 • 370 citations

Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain.

1986 • 341 citations

Molecular basis for two forms of the G protein that stimulates adenylate cyclase.

1986 • 319 citations

Selection of a Variant Lymphoma Cell Deficient in Adenylate Cyclase

1975 • 276 citations

Molecular Cloning of Complementary DNA for the Alpha Subunit of the G Protein that Stimulates Adenylate Cyclase

1985 • 209 citations

Deduced primary structure of the alpha subunit of the GTP-binding stimulatory protein of adenylate cyclase.

1986 • 177 citations

Reconstitution of catecholamine-sensitive adenylate cyclase activity: interactions of solubilized components with receptor-replete membranes.

1977 • 175 citations

Adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of S49 mouse lymphoma cells.

1977 • 173 citations

Inhibitory and stimulatory G proteins of adenylate cyclase: cDNA and amino acid sequences of the alpha chains.

1986 • 159 citations

Primary structure of the α‐subunit of bovine adenylate cyclase‐stimulating G‐protein deduced from the cDNA sequence

1986 • 142 citations

The regulatory component of adenylate cyclase from uncoupled S49 lymphoma cells differs in charge from the wild type protein.

1980 • 92 citations

Functional expression of cloned cDNA encoding the α‐subunit of adenylate cyclase‐stimulating G‐protein

1987 • 34 citations

Complementation analysis of hormone-sensitive adenylate cyclase

1978 • 33 citations

Genetic Investigation of Adenylate Cyclase: Mutations in Mouse and Man

1981 • 7 citations