Model for action of local anaesthetics

Phase transitions and phase separations in phospholipid membranes induced by changes in temperature, pH, and concentration of bivalent cations

1975 • 756 citations

Transport and metabolism of calcium ions in nerve

1972 • 754 citations

The Permeability of the Sodium Channel to Organic Cations in Myelinated Nerve

1971 • 751 citations

Negative surface charge near sodium channels of nerve: divalent ions, monovalent ions, and pH

1975 • 599 citations

The effect of temperature on the electrical activity of the giant axon of the squid

1949 • 555 citations

Structure of the Purple Membrane

1971 • 465 citations

Evidence for Boundary Lipid in Membranes

1973 • 461 citations

Reconstitution of a Calcium Pump Using Defined Membrane Components

1974 • 420 citations

Kinetics and steady‐state properties of the charged system controlling sodium conductance in the squid giant axon

1974 • 420 citations

Ionic selectivity, saturation, and block in sodium channels. A four-barrier model.

1975 • 400 citations

Cholesterol is excluded from the phospholipid annulus surrounding an active calcium transport protein

1975 • 391 citations

The Permeability of the Sodium Channel to Metal Cations in Myelinated Nerve

1972 • 367 citations

Effects of local anesthetics on membrane properties I. Changes in the fluidity of phospholipid bilayers

1975 • 337 citations

Spin labels as enzyme substrates Heterogeneous lipid distribution in liver microsomal membranes

1973 • 303 citations

Clusters in lipid bilayers and the interpretation of thermal effects in biological membranes

1974 • 253 citations

Preparation and Properties of Phospholipid Bilayers Containing Rhodopsin

1972 • 252 citations

The effect of anaesthetic-like molecules on the phase transition in smectic mesophases of dipalmitoyllecithin I. The normal alcohol up to C = 9 and three inhalation anaesthetics

1974 • 231 citations

Competitive Action of Calcium and Procaine on Lobster Axon

1966 • 219 citations

Functional properties of biological membranes: A physical-chemical approach

1976 • 217 citations

Binding of Large Organic Anions and Neutral Molecules by Native Bovine Serum Albumin^*

1966 • 215 citations

Effect of Ethanol on the Sodium and Potassium Conductances of the Squid Axon Membrane

1964 • 155 citations

Progress in Medicinal Chemistry.

1963 • 147 citations

Calculation of dipolar nuclear magnetic relaxation times in molecules with multiple internal rotations. II. Theoretical results for anisotropic over-all motion of the molecule, and comparison with 13C relaxation times in n -alkanes and n -alkyl bromides

1974 • 137 citations

Thermodynamic analysis of the relative effectiveness of narcotics

1948 • 132 citations

Synthesis of a new phosphatidylserine spin-label and calcium-induced lateral phase separation in phosphatidylserine-phosphatidylcholine membranes

1975 • 109 citations

Altered thermal sensitivity in injured and demyelinated nerve: A possible model of temperature effects in multiple sclerosis

1971 • 107 citations

Carbon-13 and proton nuclear magnetic resonance relaxation measurements of the lipids of sarcoplasmic reticulum membranes

1972 • 92 citations

THE EFFECTS OF HYDROSTATIC PRESSURE UPON THE NORMAL AND NARCOTIZED NERVE FIBER

1957 • 84 citations

THE ACTION OF TEMPERATURE ON THE EXCITABILITY, SPIKE HEIGHT AND CONFIGURATION, AND THE REFRACTORY PERIOD OBSERVED IN THE RESPONSES OF SINGLE MEDULLATED NERVE FIBERS

1941 • 81 citations

The binding of tritiated tetrodotoxin to squid giant axons

1975 • 80 citations

Ionized magnesium concentration in axoplasm of dialyzed squid axons

1975 • 77 citations

The membrane expansion theory of anesthesia: Direct evidence using ethanol and a high-precision density meter

1974 • 71 citations

Excitability, instability and phase transitions in squid axon membrane under internal perfusion with dilute salt solutions

1973 • 70 citations

Excitable Membranes

1972 • 61 citations

A determination of the mobility gradient in lipid bilayers by ¹³ C nuclear magnetic resonance

1976 • 54 citations

STRUCTURE AND ACTIVITY IN TETRODOTOXIN DERIVATIVES

1967 • 30 citations

Adsorbed Oxygen Inhibition of Reactions of Hydrogen with Tungsten

1972 • 26 citations

The effect of pressure on the phase diagram of mixed dipalmitoyl-dymyristoylphosphatidylcholine bilayers

1974 • 24 citations

Different Sites of Membrane Action for Tetrodotoxin and Lipid-Soluble Anesthetics

1975 • 19 citations

Comparison of the action of different barbiturates on squid axon membranes

1975 • 15 citations

Investigations of thermotropic phase changes in peripheral nerve of frog and rat. A spin label study

1975 • 9 citations

The labilization of lecithin liposomes by steroidal anaesthetics: A correlation with anaesthetic activity

1974 • 9 citations