Phosphorylation-activity relationships of AMPK and acetyl-CoA carboxylase in muscle

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The AMP‐Activated Protein Kinase

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Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase

1996 • 1,222 citations

AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle

1997 • 1,025 citations

AMP-activated protein kinase, a metabolic master switch: possible roles in Type 2 diabetes

1999 • 1,009 citations

A Role for AMP-Activated Protein Kinase in Contraction- and Hypoxia-Regulated Glucose Transport in Skeletal Muscle

2001 • 935 citations

Continuous Fatty Acid Oxidation and Reduced Fat Storage in Mice Lacking Acetyl-CoA Carboxylase 2

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Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exercise

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Malonyl-CoA, fuel sensing, and insulin resistance

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The regulation of AMP-activated protein kinase by phosphorylation

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1995 • 582 citations

Enzymatic analysis; a practical guide

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Tissue distribution of the AMP‐activated protein kinase, and lack of activation by cyclic‐AMP‐dependent protein kinase, studied using a specific and sensitive peptide assay

1989 • 437 citations

Isoform‐specific and exercise intensity‐dependent activation of 5′‐AMP‐activated protein kinase in human skeletal muscle

2000 • 431 citations

Purification and characterization of the AMP‐activated protein kinase

1989 • 413 citations

Contraction-induced Changes in Acetyl-CoA Carboxylase and 5′-AMP-activated Kinase in Skeletal Muscle

1997 • 404 citations

AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target

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Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart.

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Energy-sensing and signaling by AMP-activated protein kinase in skeletal muscle

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AMP-Activated Protein Kinase (AMPK) Is Activated in Muscle of Subjects With Type 2 Diabetes During Exercise

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AMPK signaling in contracting human skeletal muscle: acetyl-CoA carboxylase and NO synthase phosphorylation

2000 • 350 citations

Exercise Induces Isoform-Specific Increase in 5′AMP-Activated Protein Kinase Activity in Human Skeletal Muscle

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Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle

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Critical phosphorylation sites for acetyl-CoA carboxylase activity.

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Location and function of three sites phosphorylated on rat acetyl‐CoA carboxylase by the AMP‐activated protein kinase

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Identification of an isozymic form of acetyl-CoA carboxylase.

1990 • 250 citations

Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and protein kinase A

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Electrical stimulation inactivates muscle acetyl-CoA carboxylase and increases AMP-activated protein kinase

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Role of reversible phosphorylation of acetyl‐CoA carboxylase in long‐chain fatty acid synthesis ¹

1989 • 203 citations

Activation of Malonyl-CoA Decarboxylase in Rat Skeletal Muscle by Contraction and the AMP-activated Protein Kinase Activator 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside

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Dissociation of AMP-activated protein kinase activation and glucose transport in contracting slow-twitch muscle.

2000 • 177 citations

On the incorporation of Mg and the role of oxygen, silicon, and hydrogen in GaN prepared by reactive molecular beam epitaxy

1997 • 167 citations

Phosphorylation control of cardiac acetyl‐CoA carboxylase by cAMP‐dependent protein kinase and 5′‐AMP activated protein kinase

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Effect of exercise intensity on skeletal muscle malonyl-CoA and acetyl-CoA carboxylase

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Cloning of human acetyl-CoA carboxylase-beta and its unique features.

1996 • 148 citations

Progressive increase in human skeletal muscle AMPKα2 activity and ACC phosphorylation during exercise

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Creatine and Creatinine

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Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle.

2000 • 128 citations

Human skeletal muscle malonyl-CoA at rest and during prolonged submaximal exercise

1996 • 113 citations

Skeletal muscle malonyl-CoA content at the onset of exercise at varying power outputs in humans

1998 • 108 citations

Analysis of the Role of the AMP-Activated Protein Kinase in the Response to Cellular Stress

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1994 • 89 citations

Time course of exercise-induced decline in malonyl-CoA in different muscle types

1990 • 85 citations

Postexercise recovery of skeletal muscle malonyl-CoA, acetyl-CoA carboxylase, and AMP-activated protein kinase

1998 • 83 citations

Purification and Characterization of Rat Skeletal Muscle Acetyl-CoA Carboxylase

1995 • 80 citations

Identification of a second human acetyl-CoA carboxylase gene

1996 • 76 citations

Purification and Characterization of Rat Skeletal Muscle Acetyl-CoA Carboxylase

1995 • 64 citations

The AMP-activated Protein Kinase Gene is Highly Expressed in Rat Skeletal Muscle. Alternative Splicing and Tissue Distribution of the mRNA

1995 • 61 citations

Identification of human acetyl-CoA carboxylase isozymes in tissue and in breast cancer cells

1994 • 55 citations

The AMP-activated Protein Kinase Gene is Highly Expressed in Rat Skeletal Muscle. Alternative Splicing and Tissue Distribution of the mRNA

1995 • 53 citations

Malonyl-CoA Decarboxylase Is Not a Substrate of AMP-Activated Protein Kinase in Rat Fast-Twitch Skeletal Muscle or an Islet Cell Line

2001 • 53 citations

Regulation of mitochondrial carnitine palmitoyl transferases from liver and extrahepatic tissues

1992 • 51 citations

Influence of malonyl-CoA and palmitate concentration on rate of palmitate oxidation in rat muscle

1998 • 48 citations

Insulin stimulation of glucose uptake fails to decrease palmitate oxidation in muscle if AMPK is activated

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Effects of high fat provision on muscle PDH activation and malonyl-CoA content in moderate exercise

2000 • 46 citations