Leptin Receptor Immunoreactivity in Chemically Defined Target Neurons of the Hypothalamus

Positional cloning of the mouse obese gene and its human homologue

1994 • 12,975 citations

Weight-Reducing Effects of the Plasma Protein Encoded by the obese Gene

1995 • 4,457 citations

Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice

1995 • 4,057 citations

Identification and expression cloning of a leptin receptor, OB-R

1995 • 3,498 citations

Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

1995 • 3,302 citations

Role of leptin in the neuroendocrine response to fasting

1996 • 3,106 citations

Abnormal splicing of the leptin receptor in diabetic mice

1996 • 2,361 citations

Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db/db Mice

1996 • 2,185 citations

The role of neuropeptide Y in the antiobesity action of the obese gene product

1995 • 1,521 citations

Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin

1996 • 1,505 citations

Identification of targets of leptin action in rat hypothalamus.

1996 • 1,502 citations

STATs: Signal Transducers and Activators of Transcription

1996 • 1,414 citations

A role for melanin-concentrating hormone in the central regulation of feeding behaviour

1996 • 1,301 citations

NEUROPEPTIDE Y AND HUMAN PANCREATIC POLYPEPTIDE STIMULATE FEEDING BEHAVIOR IN RATS

1984 • 1,274 citations

Leptin enters the brain by a saturable system independent of insulin

1996 • 1,210 citations

Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y

1996 • 1,020 citations

Diabetes, a New Mutation in the Mouse

1966 • 966 citations

Localization of leptin receptor mRNA and the long form splice variant (Ob‐Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization

1996 • 879 citations

Specificity of Leptin Action on Elevated Blood Glucose Levels and Hypothalamic Neuropeptide Y Gene Expression in ob/ob Mice

1996 • 873 citations

Neuropeptide Y chronically injected into the hypothalamus: A powerful neurochemical inducer of hyperphagia and obesity

1986 • 856 citations

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors.

1996 • 820 citations

Attenuation of the Obesity Syndrome of ob/ob Mice by the Loss of Neuropeptide Y

1996 • 814 citations

Defective STAT signaling by the leptin receptor in diabetic mice.

1996 • 803 citations

Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues

1997 • 771 citations

Effects of parabiosis of obese with diabetes and normal mice

1973 • 728 citations

Crystal structure of the obese protein Ieptin-E100

1997 • 658 citations

Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily.

1992 • 525 citations

An arcuato-paraventricular and -dorsomedial hypothalamic neuropeptide Y-containing system which lacks noradrenaline in the rat

1985 • 523 citations

Coexpression of Leptin Receptor and Preproneuropeptide Y mRNA in Arcuate Nucleus of Mouse Hypothalamus

1996 • 473 citations

Model for the regulation of energy balance and adiposity by the central nervous system

1999 • 339 citations

The Leptin Receptor Activates Janus Kinase 2 and Signals for Proliferation in a Factor-Dependent Cell Line

1997 • 315 citations

Expression and Localization of the Leptin Receptor in Endocrine and Neuroendocrine Tissues of the Rat

1997 • 313 citations

Three different mRNAs encoding human granulocyte colony-stimulating factor receptor.

1990 • 304 citations

Identification of a cDNA Encoding a Long Form of Prolactin Receptor in Human Hepatoma and Breast Cancer Cells

1989 • 274 citations

Immunohistochemical localization of a melanin concentrating hormone-like peptide in the rat brain

1985 • 267 citations

Effects of PVN galanin on macronutrient selection

1988 • 252 citations

The hypothalamic arcuate nucleus-median eminence complex: Immunohistochemistry of transmitters, peptides and DARPP-32 with special reference to coexistence in dopamine neurons

1986 • 231 citations

The hypothalamic arcuate nucleus-median eminence complex: Immunohistochemistry of transmitters, peptides and DARPP-32 with special reference to coexistence in dopamine neurons

1986 • 210 citations

Endorphinergic mechanisms in the control of food and water intake

1981 • 183 citations

Distribution and Coexistence of Corticotropin-Releasing Factor-, Neurotensin-, Enkephalin-, Cholecystokinin-, Galanin- and Vasoactive Intestinal Polypeptide/Peptide Histidine Isoleucine-Like Peptides in the Parvocellular Part of the Paraventricular Nucleus

1989 • 166 citations

Expression of leptin receptor mRNA in the hypothalamic arcuate nucleus - relationship with NPY neurones

1996 • 164 citations

Localization of leptin receptor mRNA expression in mouse brain

1996 • 159 citations

Localization of neuropeptide Y Y1 receptors in the rat nervous system with special reference to somatic receptors on small dorsal root ganglion neurons.

1994 • 142 citations

Stimulation of food intake in rats by centrally administered hypothalamic growth hormone-releasing factor

1985 • 133 citations

Regulation of leptin receptor and NPY gene expression in hypothalamus of leptin‐treated obese (ob/ob) and cold‐exposed lean mice

1997 • 130 citations

New model for the regulation of energy balance and adiposity by the central nervous system

1995 • 98 citations

The Loop System Between Neuropeptide Y and Leptin in Normal and Obese Rodents

1996 • 93 citations

Morphology and function of capillary networks in subregions of the rat tuber cinereum

1992 • 84 citations

The Leptin Receptor Activates Janus Kinase 2 and Signals for Proliferation in a Factor-Dependent Cell Line

1997 • 66 citations

Gene expression and chemical diversity in hypothalamic neurosecretory neurons

1993 • 60 citations

Neuropeptide Y stimulates β-endorphin release in the basal hypothalamus: role of gonadal steroids

1995 • 30 citations

Monosodium Glutamate (MSG) Lesions

1991 • 19 citations

Bcl-2 Overexpression Does Not Prevent but Retards Adriamycin Toxicity in CC531 Colon Carcinoma Cells

2003 • 14 citations