Native Kv1.3 Channels are Upregulated by Protein Kinase C

Protein kinase C isoenzymes: divergence in signal transduction?

1993 • 1,237 citations

Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C

1989 • 1,126 citations

Inactivation properties of voltage-gated K+ channels altered by presence of β-subunit

1994 • 845 citations

Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain.

1989 • 765 citations

Auxiliary subunits of voltage-gated ion channels

1994 • 561 citations

Potassium and Calcium Channels in Lymphocytes

1995 • 488 citations

The mechanism of protein kinase C activation

1989 • 423 citations

A voltage‐gated potassium channel in human T lymphocytes.

1985 • 403 citations

Inhibition of protein kinase C by calphostin C is light-dependent

1991 • 374 citations

Modulation of ion channel activity: a key function of the protein kinase C enzyme family.

1989 • 338 citations

Voltage-gated potassium channels are required for human T lymphocyte activation.

1984 • 337 citations

Heteropolymeric potassium channels expressed in xenopus oocytes from cloned subunits

1990 • 247 citations

Voltage-gated potassium channels regulate calcium-dependent pathways involved in human T lymphocyte activation.

1993 • 242 citations

Selective blockers of voltage-gated K+ channels depolarize human T lymphocytes: mechanism of the antiproliferative effect of charybdotoxin.

1992 • 239 citations

Ion channels in leukocytes.

1991 • 191 citations

Expression and chromosomal localization of a lymphocyte K+ channel gene.

1990 • 170 citations

Heterologous expression of specific K+ channels in T lymphocytes: functional consequences for volume regulation.

1993 • 155 citations

Properties of K ⁺ and Cl ⁻ channels and their involvement in proliferation of rat microglial cells

1996 • 151 citations

Voltage‐gated potassium conductance in human T lymphocytes stimulated with phorbol ester.

1986 • 151 citations

A Family of Three Mouse Potassium Channel Genes with Intronless Coding Regions

1990 • 150 citations

Elimination of rapid potassium channel inactivation by phosphorylation of the inactivation gate

1994 • 148 citations

Cloning, functional expression, and regulation of two K+ channels in human T lymphocytes.

1992 • 134 citations

Phosphorylation by protein kinase A enhances delayed rectifier K+ current in rabbit vascular smooth muscle cells

1995 • 129 citations

Osmotic and phorbol ester-induced activation of Na+/H+ exchange: possible role of protein phosphorylation in lymphocyte volume regulation.

1985 • 117 citations

Regulation of Shaker K+ channel inactivation gating by the cAMP-dependent protein kinase

1994 • 110 citations

Voltage‐dependent potassium channels in activated rat microglia.

1994 • 110 citations

Staurosporine, a protein kinase C inhibitor interferes with proliferation of arterial smooth muscle cells

1989 • 106 citations

Elevation of intracellular calcium reduces voltage-dependent potassium conductance in human T cells

1986 • 105 citations

Potassium channels mediate killing by human natural killer cells.

1986 • 101 citations

Activation of resting human T cells requires prolonged stimulation of protein kinase C.

1990 • 99 citations

Characterization and functional expression of a rat genomic DNA clone encoding a lymphocyte potassium channel.

1990 • 98 citations

Distinct voltage-dependent regulation of a heart-delayed IK by protein kinases A and C

1991 • 97 citations

Evidence for voltage modulation of IL-2 production in mitogen-stimulated human peripheral blood lymphocytes.

1992 • 95 citations

Divalent ion trapping inside potassium channels of human T lymphocytes.

1989 • 84 citations

Modulation of potassium channels in human T lymphocytes: effects of temperature.

1990 • 75 citations

Full-length and truncated Kv1.3 K+ channels are modulated by 5-HT1c receptor activation and independently by PKC

1993 • 71 citations

Opposite effects of phosphatase inhibitors on L‐type calcium and delayed rectifier currents in frog cardiac myocytes.

1993 • 67 citations

Protein kinase C pseudosubstrate prototope: Structure-function relationships

1990 • 66 citations

Differential regulation of voltage- and calcium-activated potassium channels in human B lymphocytes.

1992 • 64 citations

Dual regulation of the n type K+ channel in Jurkat T lymphocytes by protein kinases A and C.

1992 • 62 citations

Modulation of K+ currents in human lymphocytes by pH.

1989 • 59 citations

Modulation of vertebrate brain Na⁺ and K⁺ channels by subtypes of protein kinase C

1990 • 53 citations

State-dependent inactivation of K+ currents in rat type II alveolar epithelial cells.

1990 • 52 citations

Characterization and Functional Expression of Genomic DNA Encoding the Human Lymphocyte TypenPotassium Channel

1992 • 49 citations

In vivo and in vitro phosphorylation of the T lymphocyte type n (Kv1.3) potassium channel.

1993 • 48 citations

Modulation of potassium channels in intact human T lymphocytes.

1992 • 47 citations

Intracellular and extracellular amino acids that influence C-type inactivation and its modulation in a voltage-dependent potassium channel

1995 • 47 citations

Dual effects of serotonin on a voltage-gated conductance in lymphocytes.

1988 • 46 citations

Heterogeneity of protein kinase C expression and regulation in T lymphocytes

1990 • 46 citations

Phorbol ester synergizes with Ca2+ ionophore in activation of protein kinase C (PKC)alpha and PKC beta isoenzymes in human T cells and in induction of related cellular functions.

1992 • 44 citations

Modulation of K channels in dialyzed squid axons. ATP-mediated phosphorylation.

1989 • 33 citations

Translocation of the α‐ and β‐isoforms of protein kinase C following activation of human T‐lymphocytes

1991 • 24 citations

Ion channels as sensors of cellular energy

1993 • 20 citations

Properties of a potassium-selective ion channel in human melanoma cells

1990 • 12 citations

Differential expression of PKCα and PKCβ isozymes in CD4⁺, CD8⁺ and CD4⁺/CD8⁺ double positive human T cells

1994 • 7 citations