Back to search

Antitumor immune response by CX3CL1 fractalkine gene transfer depends on both NK and T cells

Data up to Jan 2025

Published2005
Citations83
References42

Total Citations Per Year

Abstract

References (42)

Involvement of chemokine receptors in breast cancer metastasis

2001 • 5,203 citations

A Progress Report on the Treatment of 157 Patients with Advanced Cancer Using Lymphokine-Activated Killer Cells and Interleukin-2 or High-Dose Interleukin-2 Alone

1987 • 2,769 citations

Chemokines and leukocyte traffic

1998 • 2,755 citations

The Biology of Chemokines and their Receptors

2000 • 2,416 citations

Analysis of Fractalkine Receptor CX3CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion

2000 • 2,356 citations

A new class of membrane-bound chemokine with a CX3C motif

1997 • 1,964 citations

Cytokines in cancer pathogenesis and cancer therapy

2004 • 1,465 citations

Identification and Molecular Characterization of Fractalkine Receptor CX3CR1, which Mediates Both Leukocyte Migration and Adhesion

1997 • 1,406 citations

Progress in human tumour immunology and immunotherapy

2001 • 1,327 citations

Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant.

1994 • 1,190 citations

Escape of Human Solid Tumors from T–Cell Recognition: Molecular Mechanisms and Functional Significance

1999 • 1,168 citations

The Role of Chemokine Receptors in Primary, Effector, and Memory Immune Responses

2000 • 1,077 citations

Dendritic Cell Subsets and Lineages, and Their Functions in Innate and Adaptive Immunity

2001 • 1,010 citations

The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion

2003 • 686 citations

Tumor Necrosis Factor-α-converting Enzyme (ADAM17) Mediates the Cleavage and Shedding of Fractalkine (CX3CL1)

2001 • 623 citations

Fractalkine Preferentially Mediates Arrest and Migration of CD16+ Monocytes

2003 • 563 citations

Inhibition of interleukin-8 reduces tumorigenesis of human non-small cell lung cancer in SCID mice.

1996 • 405 citations

Cytokines as a link between innate and adaptive antitumor immunity

2002 • 321 citations

Dual Functions of Fractalkine/CX3C Ligand 1 in Trafficking of Perforin+/Granzyme B+ Cytotoxic Effector Lymphocytes That Are Defined by CX3CR1 Expression

2002 • 320 citations

Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses

2001 • 318 citations

Current Developments in Cancer Vaccines and Cellular Immunotherapy

2003 • 300 citations

Effective eradication of established murine tumors with IL-12 gene therapy using a polycistronic retroviral vector.

1995 • 277 citations

Dendritic and Natural Killer Cells Cooperate in the Control/Switch of Innate Immunity

2002 • 277 citations

Chemokines: Roles in leukocyte development, trafficking, and effector function

2003 • 259 citations

CX3C-Chemokine, Fractalkine-Enhanced Adhesion of THP-1 Cells to Endothelial Cells Through Integrin-Dependent and -Independent Mechanisms

2000 • 227 citations

Fractalkine, a CX3C chemokine, is expressed by dendritic cells and is up-regulated upon dendritic cell maturation

1999 • 174 citations

Recombinant interferon alfa-2a with or without vinblastine in metastatic renal cell carcinoma: Results of a European multi-center phase III study

1992 • 131 citations

Fractalkine mediates natural killer-dependent antitumor responses in vivo.

2003 • 112 citations

Fractalkine and macrophage-derived chemokine: T cell-attracting chemokines expressed in T cell area dendritic cells

1999 • 109 citations

Inhibition of interleukin-2-induced tumor necrosis factor release by dexamethasone: prevention of an acquired neutrophil chemotaxis defect and differential suppression of interleukin-2-associated side effects [see comments]

1990 • 109 citations

CX3CR1 Tyrosine Sulfation Enhances Fractalkine-induced Cell Adhesion

2002 • 102 citations

Antitumor effect and cellular immunity activation by murine interferon-β gene transfer against intracerebral glioma in mouse

1999 • 98 citations

Signal transduction pathways involved in soluble fractalkine–induced monocytic cell adhesion

2001 • 92 citations

Fractalkine transgene induces T‐cell‐dependent antitumor immunity through chemoattraction and activation of dendritic cells

2002 • 76 citations

Macrophage-derived chemokine gene transfer results in tumor regression in murine lung carcinoma model through efficient induction of antitumor immunity

2002 • 58 citations

Chemoattraction, adhesion and activation of natural killer cells are involved in the antitumor immune response induced by fractalkine/CX3CL1

2003 • 57 citations

Antitumor effect by interleukin-11 receptor alpha-locus chemokine/CCL27, introduced into tumor cells through a recombinant adenovirus vector.

2003 • 48 citations

Transfection of interleukin 2 gene into human melanoma cells augments cellular immune response.

1993 • 41 citations

Lentiviral transduction of human T-lymphocytes with a RANTES intrakine inhibits human immunodeficiency virus type 1 infection

2002 • 41 citations

Biochemotherapy for advanced melanoma

2002 • 31 citations

Chest Roentgenographic Abnormalities in IL-2 Recipients

1992 • 29 citations

Lymphotactin cotransfection enhances the therapeutic efficacy of dendritic cells genetically modified with melanoma antigen gp100

2002 • 27 citations

Cited By (0)

Loading...
Antitumor immune response by CX3CL1 fractalkine gene transfer depends on both NK and T… (2005) – European Journal of Immunology | Metascience Observatory Explorer