The role of autoreactive T-cell lines in the restoration of the immune response to sheep red blood cells in C57B16-lprlpr mice

Plaque Formation in Agar by Single Antibody-Producing Cells

1963 • 2,385 citations

Further improvements in the plaque technique for detecting single antibody-forming cells.

1968 • 2,171 citations

Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains.

1978 • 1,619 citations

Analysis of T cell function in autoimmune murine strains. Defects in production and responsiveness to interleukin 2.

1981 • 334 citations

Deficient interleukin 2 activity in MRL/Mp and C57BL/6J mice bearing the lpr gene.

1981 • 237 citations

Identification of a B cell differentiation factor(s) spontaneously produced by proliferating T cells in murine lupus strains of the lpr/lpr genotype.

1983 • 188 citations

The Autologous Mixed-Lymphocyte Reaction

1981 • 181 citations

Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes.

1979 • 167 citations

Decreased autologous mixed lymphocyte reaction in Sjögren's syndrome.

1980 • 153 citations

Specificity and Suppressor Function of Human T Cells Responsive to Autologous Non-T Cells

1979 • 148 citations

Alloreactive cloned T cell lines. VI. Multiple lymphokine activities secreted by helper and cytolytic cloned T lymphocytes.

1982 • 145 citations

The cellular basis of the impaired autologous mixed lymphocyte reaction in patients with systemic lupus erythematosus.

1979 • 143 citations

Specificity and function of a human autologous reactive T cell.

1979 • 140 citations

Murine syngeneic mixed lymphocyte response. I. Target antigens are self Ia molecules

1981 • 131 citations

Induction of suppressor activity in the autologous mixed lymphocyte reaction and in cultures with concanavalin A.

1979 • 112 citations

Delineation of an immunoregulatory amplifier population recognizing autologous Ia molecules. Analysis with human T cell clones.

1984 • 90 citations

Immunoregulatory activities of autoreactive T cells: an I-A-specific T cell clone mediates both help and suppression of antibody responses.

1984 • 87 citations

The lymphoproliferating cells of MRL‐lpr/lpr mice are a polyclonal population that bear the T lymphocyte receptor for antigen

1985 • 80 citations

Immunoglobulin secretion in the human autologous mixed leukocyte reaction. Definition of a suppressor-amplifier circuit using monoclonal antibodies.

1982 • 76 citations

The autologous mixed lymphocyte reaction in strains of mice with autoimmune disease.

1980 • 72 citations

Helper factors derived from autologous mixed lymphocyte cultures

1980 • 69 citations

Spontaneous production of interleukin 3 by T lymphocytes from autoimmune MRL/MP‐lpr/lpr mice

1984 • 59 citations

Alloreactive cloned T cell lines. V. Differential kinetics of IL 2, CSF, and BCSF release by a cloned T amplifier cell and its variant.

1981 • 58 citations

Antibody response to phosphorylcholine in vitro. I. Studies on the frequency of precursor cells, average clone size and cellular cooperation

1975 • 47 citations

Immunoregulation by T cells. I. Characterization of the IEk-specific Lbd self-reactive T cell clone that helps, suppresses and contrasupresses B cell responses.

1986 • 39 citations

Comparison of antigen-specific T cell responses in autoimmune MRL/Mp-lpr/lpr and MRL/Mp-+/+ mice.

1984 • 30 citations

Thymic Influences on Autoimmunity in MRL‐1pr Mice

1982 • 30 citations

Limiting dilution analysis of interleukin 2 and colony-stimulating factor producer cells in normal and autoimmune mice.

1984 • 28 citations

Defective T cell response to presented antigen in autoimmune mice.

1984 • 28 citations

Selective stimulation by B lymphocytes in the syngeneic mixed lymphocyte reaction

1974 • 25 citations

T cell regulation of antibody responses: an I-A-specific, autoreactive T cell collaborates with antigen-specific helper T cells to promote IgG responses.

1985 • 21 citations

A subset of Ly-1 inducer T cell clones activates B cell proliferation but directly inhibits subsequent IgG secretion.

1985 • 16 citations

Signals required for activation and growth of autoimmune T lymphocytes.

1984 • 15 citations

Immunoregulation in MRL/Mp-lpr/lpr mice: Evidence for decreased helper-T-cell and increased suppressor-T-cell function with age

1982 • 12 citations

The syngeneic T-T lymphocyte reaction (STTLR). I. Induction of primary T anti-T cell proliferative responses in T cell cultures stimulated with self- and antigen-reactive T cells.

1986 • 6 citations