Murine syngeneic mixed lymphocyte response. I. Target antigens are self Ia molecules

A rapid method for the isolation of functional thymus‐derived murine lymphocytes

1973 • 4,203 citations

The somatic generation of immune recognition

1971 • 974 citations

In a radiation chimaera, host H–2 antigens determine immune responsiveness of donor cytotoxic cells

1977 • 534 citations

Why do so many lymphocytes respond to major histocompatibility antigens?

1977 • 462 citations

Contribution of dendritic cells to stimulation of the murine syngeneic mixed leukocyte reaction.

1980 • 329 citations

Two-gene control of the expression of a murine Ia antigen.

1978 • 328 citations

Autologous stimulation of human lymphocyte subpopulation.

1975 • 323 citations

Lymphocyte transformation induced by autologous cells. IV. Human T-lymphocyte proliferation induced by autologous or allogeneic non-T lymphocytes.

1976 • 298 citations

Thymus and Lymphohemopoietic Cells: Their Role in T Cell Maturation in Selection of T Cells' H‐2‐Restriction‐Specificity and in H‐2 Linked Ir Gene Control

1978 • 291 citations

The Influence of Thymus H-2 Antigens on the Specificity of Maturing Killer and Helper Cells

1978 • 257 citations

Cytotoxic T cells learn specificity for self H–2 during differentiation in the thymus

1978 • 219 citations

Lymphocyte transformation induced by autologous cells. V. generation of immunologic memory and specificity during the autologous mixed lymphocyte reaction

1977 • 215 citations

Macrophage heterogeneity in man. A subpopulation of HLA-DR-bearing macrophages required for antigen-induced T cell activation also contains stimulators for autologous-reactive T cells.

1980 • 198 citations

Two Different V_H Gene Products Make Up the T‐Cell Receptors

1976 • 179 citations

Self recognition in allogeneic radiation bone marrow chimeras. A radiation- resistant host element dictates the self specificity and immune response gene phenotype of T-helper cells

1981 • 164 citations

A Clonal Deletion Model for Ir Gene Control of the Immune Response

1978 • 156 citations

Role of H‐2 Gene Products in the Function of T Helper Cells from Normal and Chimeric Mice in Vivo¹

1978 • 153 citations

T-cell specificity for H–2 and Ir gene phenotype correlates with the phenotype of thymic antigen-presenting cells

1980 • 153 citations

Association of immunity and tolerance to host H-2 determinants in irradiated F1 hybrid mice reconstituted with bone marrow cells from one parental strain.

1975 • 140 citations

The role of H-2 linked genes in helper T-cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expression.

1978 • 134 citations

Syngeneic Mixed Lymphocyte Reaction in Mice: Strain Distribution, Kinetics, Participating Cells, and Absence in NZB Mice

1978 • 126 citations

Cell-mediated immunity and the major histocompatibility complex

1978 • 119 citations

In a fully H-2 incompatible chimera, T cells of donor origin can respond to minor histocompatibility antigens in association with either donor or host H-2 type.

1978 • 108 citations

Nature of the antigenic complex recognized by T lymphocytes. I. Analysis with an in vitro primary response to soluble protein antigens.

1976 • 101 citations

Thymic Maturation in Vitro by a Secretory Product from Macrophages

1977 • 93 citations

Adaptive differentiation of murine lymphocytes. I. Both T and B lymphocytes differentiating in F1 transplanted to parental chimeras manifest preferential cooperative activity for partner lymphocytes derived from the same parental type corresponding to the chimeric host.

1978 • 84 citations

T cells and macrophages involved in the autologous mixed lymphocyte reaction are required for the response to conventional antigen.

1980 • 84 citations

The autologous mixed lymphocyte reaction in strains of mice with autoimmune disease.

1980 • 72 citations

The syngeneic mixed leukocyte reaction: the genetic requirements for the recognition of self resemble the requirements for the recognition of antigen in association with self.

1980 • 69 citations

Stimulating cell types in the autologous mixed leukocyte reaction in man.

1980 • 62 citations

The Influence of the Major Histocompatibility Complex on the Function of T‐Helper Cells in Antibody Formation

1978 • 58 citations

Syngeneic Mixed Lymphocyte Reaction between Thymocytes and Peripheral Lymphoid Cells in Mice: Strain Specificity and Nature of the Target Cell

1973 • 53 citations

Gene complementation. Neither Ir-GLphi gene need be present in the proliferative T cell to generate an immune response to Poly(Glu55Lys36Phe9)n.

1980 • 50 citations

Adult Murine Lymph Node Cells Respond Blastogenically to a New Differentiation Antigen on Isologous and Autologous B Lymphocytes

1975 • 48 citations

Restrictions Imposed on T Lymphocyte Reactivities by the Major Histocompatibility Complex: Implications for T Cell Repertoire Selection

1978 • 46 citations

Anamnestic responses in mixed lymphocyte culture-induced cytolysis (MLC-CML) reaction

1976 • 43 citations

Studies on the generation and expression of H‐2‐controlled T helper function in chimeric mice: Evidence for two levels of H‐2 restriction

1979 • 40 citations

Primary anti-viral cytotoxic T-cell responses in semiallogeneic chimeras are not absolutely restricted to host H-2 type.

1979 • 39 citations

Cellular and genetic control of antibody responses. VI. Expression of Ir gene function by H-2a accessory cells, but not H-2a T or B cells in responses to TNP-(T,G)-A--L.

1979 • 35 citations

Genetic control of the immune response to collagen. II. Antibody responses produced in fetal liver restored radiation chimeras and thymus reconstituted F1 hybrid nude mice.

1979 • 31 citations

Inhibition of antigen-induced proliferation of T cells from radiation-induced bone marrow chimeras by a monoclonal antibody directed against an Ia determinant on the antigen-presenting cell.

1981 • 25 citations

Features of cells controlling H-2-restricted presentation of antigen to T helper cells in vivo.

1980 • 18 citations

Complementation between I region genes is revealed by a hybridoma anti-Ia antibody.

1981 • 13 citations