Aberrant crypts in human colonic mucosa: Putative preneoplastic lesions

Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: Preliminary findings

1987 • 1,036 citations

Aberrant crypts: putative preneoplastic foci in human colonic mucosa.

1991 • 448 citations

Small “flat adenoma” of the large bowel with special reference to its clinicopathologic features

1985 • 425 citations

Identification and quantification of aberrant crypt foci and microadenomas in the human colon

1991 • 316 citations

Aberrant crypts: potential preneoplastic lesions in the murine colon.

1988 • 305 citations

Familial Polyposis Coli. Family Studies, Histopathology, Differential Diagnosis, and Results of Treatment.

1975 • 300 citations

Mutagens and Carcinogens in the Diet

1991 • 239 citations

Gastrointestinal Pathology

1980 • 236 citations

Foci of aberrant crypts in the colons of mice and rats exposed to carcinogens associated with foods.

1989 • 164 citations

Minute cancers arising de novo in the human large intestine

1988 • 138 citations

Aberrant crypts, putative precancerous lesions, in the study of the role of diet in the aetiology of colon cancer.

1989 • 114 citations

Observations on the origin of adenomatous epithelium of the colon.Serial section studies of minute polyps in familial polyposis

1963 • 99 citations

Experimentally induced cancer of the colon

1974 • 98 citations

Specificity study to evaluate induction of aberrant crypts in murine colons.

1988 • 97 citations

Promotion of colonic microadenoma growth in mice and rats fed cooked sugar or cooked casein and fat.

1990 • 87 citations

Colon Epithelium. II. In Vivo Studies of Colon Carcinogenesis. Light Microscopic, Histochemical, and Ultrastructural Studies of Histogenesis of Azoxymethane-Induced Colon Carcinomas in Fischer 344 Rats<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref><xref ref-type="fn" rid="fn4">4</xref><xref ref-type="fn" rid="fn5">5</xref>

1981 • 86 citations

Mucin abnormality of colonic mucosa in patients with familial polyposis coli

1985 • 80 citations

Growth kinetics and chemoprevention of aberrant crypts in the rat colon

1992 • 68 citations

Depressed adenoma in the large intestine

1990 • 60 citations

Morphogenesis of Minute Adenomas in Familial Polyposis Coli<xref ref-type="fn" rid="FN2">2</xref>

1984 • 58 citations

β Hexosaminidase isozymes in human colonic carcinoma

1977 • 57 citations

Effect of disulfiram on 1,2-dimethlhydrazine- and azoxymethane- induced aberrant crypt foci

1991 • 51 citations

Glycoprotein metabolism in normal proximal and distal rat colon and changes associated with 1,2-dimethylhydrazine-induced colonic neoplasia.

1978 • 49 citations

Effect of dietary carbohydrates on the growth of dysplastic crypt foci in the colon of rats treated with 1,2-dimethylhydrazine.

1991 • 49 citations

Surface changes in the descending colon of rats treated with dimethylhydrazine.

1977 • 48 citations

Characterization of stereomicroscopically identified preneoplastic lesions during dimethylhydrazine‐induced colonic carcinogenesis

1988 • 45 citations

Colonic aberrant crypts in azoxymethane-treated F344 rats have decreased hexosaminidase activity.

1990 • 41 citations

Examination of enzyme-altered foci with gamma-glutamyl transpeptidase, aldehyde dehydrogenase, glucose-6-phosphate dehydrogenase, and other markers in methacrylate-embedded liver.

1987 • 39 citations

Detection of early neoplastic changes in experimentally induced colorectal cancer using scanning electron microscopy and cell kinetic studies.

1984 • 34 citations

Precursors of human colon carcinoma: A serial section study of colectomy specimens

1981 • 33 citations

Enzyme-altered foci in colons of carcinogen-treated rats.

1990 • 28 citations

Studies on the difference of background mucosa among single advanced carcinoma and benign diseases of the large intestine, and familial polyposis coli

1980 • 27 citations

Nuclear DNA content in dimethylhydrazine-induced colonic carcinoma and mucosal dysplasia in rats

1984 • 15 citations

Sequential histochemical and morphometric studies on preneoplastic and neoplastic lesions induced in rat colon by 1 ,2-dimethylhydrazine

1987 • 14 citations

In situ localization of enzymes and mucin in normal rat colon embedded in plastic

1989 • 12 citations

Comparative study of familial polyposis coli and nonpolyposis coli on the histogenesis of large-intestinal adenoma

1982 • 8 citations

Aberrant crypt foci in the detection of colon carcinogens.

1990 • 7 citations