Cyclic AMP induction of early adenovirus promoters involves sequences required for E1A trans-activation.

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

1987 • 1,364 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

An adenovirus type 5 early gene function regulates expression of other early viral genes.

1979 • 791 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription

1984 • 458 citations

Tissue-specific enhancer of the human glycoprotein hormone alpha-subunit gene: dependence on cyclic AMP-inducible elements.

1987 • 409 citations

Adenovirus E1a proteins repress transcription from the SV40 early promoter

1985 • 366 citations

Multiple functional domains in the adenovirus E1A gene

1987 • 361 citations

An adenovirus E1a protein region required for transformation and transcriptional repression

1986 • 329 citations

c-fos Sequence Necessary for Basal Expression and Induction by Epidermal Growth Factor, 12-O-Tetradecanoyl Phorbol-13-Acetate and the Calcium Ionophore

1987 • 304 citations

Proto-oncogene fos: Complex but versatile regulation

1987 • 296 citations

Transcriptional activation and subsequent control of the human heat shock gene during adenovirus infection.

1983 • 295 citations

Definition of multiple, functionally distinct TATA elements, one of which is a target in the hsp70 promoter for E1A regulation

1988 • 292 citations

A cellular protein, activating transcription factor, activates transcription of multiple E1A-inducible adenovirus early promoters.

1987 • 284 citations

A TATA box implicated in E1A transcriptional activation of a simple adenovirus 2 promoter

1987 • 227 citations

Repression of the Immunoglobulin Heavy Chain Enhancer by the Adenovirus-2 E1A Products

1985 • 223 citations

A trans-acting factor is responsible for the simian virus 40 enhancer activity in vitro

1985 • 196 citations

Identification of factors that interact with the E1A-inducible adenovirus E3 promoter.

1987 • 189 citations

HeLa Cell β-Tubulin Gene Transcription Is Stimulated by Adenovirus 5 in Parallel with Viral Early Genes by an E1a-Dependent Mechanism

1984 • 187 citations

E1A Control of Gene Expression Is Mediated by Sequences 5′ to the Transcriptional Starts of the Early Viral Genes

1983 • 169 citations

Individual products of the adenovirus 12S and 13S EIa mRNAs stimulate viral EIIa and EIII expression at the transcriptional level.

1984 • 138 citations

Transcriptional Activation and Subsequent Control of the Human Heat Shock Gene During Adenovirus Infection

1983 • 131 citations

An enhancer-like element in the adenovirus E2 promoter contains sequences essential for uninduced and E1A-induced transcription.

1985 • 131 citations

Clonal variants of PC12 pheochromocytoma cells with defects in cAMP-dependent protein kinases induce ornithine decarboxylase in response to nerve growth factor but not to adenosine agonists.

1985 • 113 citations

The adenovirus-2 early EIIa transcription unit possesses two overlapping promoters with different sequence requirements for EIa-dependent stimulation.

1985 • 111 citations

A mutated polyoma virus enhancer which is active in undifferentiated embryonal carcinoma cells is not repressed by adenovirus-2 E1A products

1986 • 104 citations

Two promoter-specific host factors interact with adjacent sequences in an EIA-inducible adenovirus promoter.

1987 • 74 citations

Activation of a preexisting cellular factor as a basis for adenovirus E1A-mediated transcription control.

1988 • 74 citations

Tissue-Specific Enhancer of the Human Glycoprotein Hormone α-Subunit Gene: Dependence on Cyclic AMP-Inducible Elements

1987 • 71 citations

Transcriptional analysis of the adenovirus-5 EIII promoter: absence of sequence specificity for stimulation by EIa gene products

1985 • 70 citations

Upstream regulatory regions required to stabilize binding to the TATA sequence in an adesovirus early promoter

1987 • 57 citations

Promoter trans-activation of protooncogenes c-fos and c-myc, but not c-Ha-ras, by products of adenovirus early region 1A.

1987 • 52 citations

The immunoglobulin heavy chain enhancer is stimulated by the adenovirus type 2 E1A products in mouse fibroblasts.

1986 • 47 citations

Far upstream sequences are required for efficient transcription from the adenovirus-2 E1A transcription unit

1983 • 42 citations

Clonal Variants of PC12 Pheochromocytoma Cells with Defects in cAMP-Dependent Protein Kinases Induce Ornithine Decarboxylase in Response to Nerve Growth Factor but not to Adenosine Agonists

1985 • 27 citations