Direct Binding of pRb/E2F-2 to GATA-1 Regulates Maturation and Terminal Cell Division during Erythropoiesis

Effects of an Rb mutation in the mouse

1992 • 1,779 citations

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

1991 • 1,321 citations

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

1992 • 1,285 citations

Requirement for a functional Rb-1 gene in murine development

1992 • 1,015 citations

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

2002 • 751 citations

Mammalian Cells Cycle without the D-Type Cyclin-Dependent Kinases Cdk4 and Cdk6

2004 • 750 citations

FOG, a Multitype Zinc Finger Protein, Acts as a Cofactor for Transcription Factor GATA-1 in Erythroid and Megakaryocytic Differentiation

1997 • 723 citations

Mouse Development and Cell Proliferation in the Absence of D-Cyclins

2004 • 630 citations

Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1

2000 • 505 citations

Extra-embryonic function of Rb is essential for embryonic development and viability

2003 • 383 citations

Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG

1998 • 352 citations

PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding

2000 • 351 citations

Erythroid-Cell-Specific Properties of Transcription Factor GATA-1 Revealed by Phenotypic Rescue of a Gene-Targeted Cell Line

1997 • 351 citations

Retinoblastoma protein partners

2001 • 348 citations

A GATA-1-regulated microRNA locus essential for erythropoiesis

2008 • 331 citations

Alternative transcription and splicing of the human porphobilinogen deaminase gene result either in tissue-specific or in housekeeping expression.

1988 • 313 citations

Rescue of erythroid development in gene targeted GATA–1− mouse embryonic stem cells

1992 • 258 citations

Use of Altered Specificity Mutants to Probe a Specific Protein–Protein Interaction in Differentiation

1999 • 232 citations

Functions of the retinoblastoma protein

1999 • 204 citations

GATA1 in normal and malignant hematopoiesis

2004 • 194 citations

GATA-1-Mediated Proliferation Arrest during Erythroid Maturation

2003 • 192 citations

An inherited mutation leading to production of only the short isoform of GATA-1 is associated with impaired erythropoiesis

2006 • 189 citations

Cell Cycle-Regulated Expression of Mammalian CDC6 Is Dependent on E2F

1998 • 178 citations

GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis

2002 • 166 citations

Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages

2004 • 144 citations

In vivo requirements for GATA-1 functional domains during primitive and definitive erythropoiesis

2001 • 133 citations

Coregulation of GATA factors by the Friend of GATA (FOG) family of multitype zinc finger proteins

2004 • 131 citations

Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis

2008 • 129 citations

GATA factor transgenes under GATA-1 locus control rescue germline GATA-1 mutant deficiencies

2000 • 113 citations

GATA1-related leukaemias

2008 • 109 citations

The Rb tumor suppressor is required for stress erythropoiesis

2004 • 99 citations

Defective Gene Expression, S Phase Progression, and Maturation during Hematopoiesis in E2F1/E2F2 Mutant Mice

2003 • 83 citations

Erythroid-specific activity of the glycophorin B promoter requires GATA-1 mediated displacement of a repressor.

1992 • 71 citations

The level of the tissue‐specific factor GATA‐1 affects the cell‐cycle machinery

1997 • 71 citations

Knock-in Mutation of Transcription Factor GATA-3 into the GATA-1 Locus: Partial Rescue of GATA-1 Loss of Function in Erythroid Cells

1998 • 63 citations

Phosphatidylinositol 3-Kinase/Akt Induced by Erythropoietin Renders the Erythroid Differentiation Factor GATA-1 Competent for TIMP-1 Gene Transactivation

2005 • 62 citations

Gene expression regulation and domain function of hematopoietic GATA factors

2004 • 59 citations

Cell-intrinsic requirement for pRb in erythropoiesis

2004 • 55 citations

Deregulated E2f-2 Underlies Cell Cycle and Maturation Defects in Retinoblastoma Null Erythroblasts

2007 • 53 citations

A minigene containing four discrete cis elements recapitulates GATA‐1 gene expression in vivo

2002 • 52 citations

Dynamic regulation of Gata factor levels is more important than their identity

2007 • 47 citations

GATA-1 and Gfi-1B Interplay To Regulate Bcl-x_L Transcription

2007 • 40 citations

Constitutive expression of GATA-1 interferes with the cell-cycle regulation

1996 • 38 citations

Id2 leaves the chromatin of the E2F4–p130-controlled c-myc promoter during hepatocyte priming for liver regeneration

2006 • 38 citations

Different domains regulate the human erythropoietin receptor gene transcription

1994 • 25 citations

The Rb Tumor Suppressor in Stress Responses and Hematopoietic Homeostasis

2004 • 25 citations