Coregulation of GATA factors by the Friend of GATA (FOG) family of multitype zinc finger proteins

An early haematopoietic defect in mice lacking the transcription factor GATA-2

1994 • 1,412 citations

Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.

1997 • 1,138 citations

GATA4 transcription factor is required for ventral morphogenesis and heart tube formation.

1997 • 1,031 citations

Coordinated histone modifications mediated by a CtBP co-repressor complex

2003 • 782 citations

Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1.

1996 • 763 citations

FOG, a Multitype Zinc Finger Protein, Acts as a Cofactor for Transcription Factor GATA-1 in Erythroid and Megakaryocytic Differentiation

1997 • 723 citations

A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development

1997 • 683 citations

Transcription factor GATA-3 is required for development of the T-cell lineage

1996 • 614 citations

Targeted Deletion of a High-Affinity GATA-binding Site in the GATA-1 Promoter Leads to Selective Loss of the Eosinophil Lineage In Vivo

2002 • 581 citations

The GATA family (vertebrates and invertebrates)

2002 • 553 citations

Transcription Factor GATA-2 Is Required for Proliferation/Survival of Early Hematopoietic Cells and Mast Cell Formation, But Not for Erythroid and Myeloid Terminal Differentiation

1997 • 543 citations

Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1

2000 • 505 citations

Transcription Factor GATA-2 Is Required for Proliferation/Survival of Early Hematopoietic Cells and Mast Cell Formation, But Not for Erythroid and Myeloid Terminal Differentiation

1997 • 503 citations

Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1.

1990 • 422 citations

FOG-2, a Cofactor for GATA Transcription Factors, Is Essential for Heart Morphogenesis and Development of Coronary Vessels from Epicardium

2000 • 409 citations

Thicker Than Blood

2003 • 398 citations

Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation.

1995 • 361 citations

Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG

1998 • 352 citations

Erythroid-Cell-Specific Properties of Transcription Factor GATA-1 Revealed by Phenotypic Rescue of a Gene-Targeted Cell Line

1997 • 351 citations

Gonadal differentiation, sex determination and normalSryexpression in mice require direct interaction between transcription partners GATA4 and FOG2

2002 • 343 citations

GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling

2003 • 340 citations

GATA-3: an unexpected regulator of cell lineage determination in skin

2003 • 334 citations

Consequences of GATA-1 Deficiency in Megakaryocytes and Platelets

1999 • 327 citations

Cloning and characterization of mCtBP2, a co-repressor that associates with basic Kruppel-like factor and other mammalian transcriptional regulators

1998 • 320 citations

Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors

2001 • 309 citations

Molecular cloning of FOG-2: A modulator of transcription factor GATA-4 in cardiomyocytes

1999 • 279 citations

ZEB represses transcription through interaction with the corepressor CtBP

1999 • 273 citations

Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers

1999 • 266 citations

spalt encodes an evolutionarily conserved zinc finger protein of novel structure which provides homeotic gene function in the head and tail region of the Drosophila embryo.

1994 • 246 citations

Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1mutation

2001 • 236 citations

Use of Altered Specificity Mutants to Probe a Specific Protein–Protein Interaction in Differentiation

1999 • 232 citations

The corepressor CtBP interacts with Evi-1 to repress transforming growth factor β signaling

2001 • 230 citations

FOG-2, a Heart- and Brain-Enriched Cofactor for GATA Transcription Factors

1999 • 222 citations

A Palindromic Regulatory Site within Vertebrate GATA-1 Promoters Requires Both Zinc Fingers of the GATA-1 DNA-Binding Domain for High-Affinity Interaction

1996 • 221 citations

GATA-1 as a Regulator of Mast Cell Differentiation Revealed by the Phenotype of the GATA-1low Mouse Mutant

2003 • 214 citations

X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction

2002 • 213 citations

Association of COOH-terminal-binding Protein (CtBP) and MEF2-interacting Transcription Repressor (MITR) Contributes to Transcriptional Repression of the MEF2 Transcription Factor

2001 • 210 citations

FOG-2: A novel GATA-family cofactor related to multitype zinc-finger proteins Friend of GATA-1 and U-shaped

1999 • 209 citations

Ikaros Interactions with CtBP Reveal a Repression Mechanism That Is Independent of Histone Deacetylase Activity

2000 • 201 citations

X-linked thrombocytopenia caused by a novel mutation ofGATA-1

2001 • 195 citations

Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription

1993 • 192 citations

Transcriptional activity of Pannier is regulated negatively by heterodimerization of the GATA DNA-binding domain with a cofactor encoded by the u-shaped gene of Drosophila

1997 • 189 citations

A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2

2000 • 177 citations

Interaction between a Cellular Protein That Binds to the C-terminal Region of Adenovirus E1A (CtBP) and a Novel Cellular Protein Is Disrupted by E1A through a Conserved PLDLS Motif

1998 • 177 citations

GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis

2002 • 166 citations

Control of megakaryocyte-specific gene expression by GATA-1 and FOG-1: role of Ets transcription factors

2002 • 160 citations

The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila

2001 • 158 citations

Net, a negative Ras-switchable TCF, contains a second inhibition domain, the CID, that mediates repression through interactions with CtBP and de-acetylation

1999 • 146 citations

Different substitutions at residue D218 of the X-linked transcription factor GATA1 lead to altered clinical severity of macrothrombocytopenia and anemia and are associated with variable skewed X inactivation

2002 • 141 citations

u-shaped encodes a zinc finger protein that regulates the proneural genesachaete and scute during the formation of bristles in Drosophila

1997 • 139 citations

Coregulator-dependent facilitation of chromatin occupancy by GATA-1

2004 • 136 citations

Context-dependent regulation of GATA-1 by friend of GATA-1

2003 • 127 citations

The centrosomal protein TACC3 is essential for hematopoietic stem cell function and genetically interfaces with p53-regulated apoptosis

2002 • 122 citations

A Functionally Conserved N-terminal Domain of the Friend of GATA-2 (FOG-2) Protein Represses GATA4-Dependent Transcription

2000 • 121 citations

Antagonism between C/EBPβ and FOG in eosinophil lineage commitment of multipotent hematopoietic progenitors

2000 • 117 citations

The Interaction of the Carboxyl Terminus-binding Protein with the Smad Corepressor TGIF Is Disrupted by a Holoprosencephaly Mutation in TGIF

2000 • 106 citations

hFOG-2, a Novel Zinc Finger Protein, Binds the Co-repressor mCtBP2 and Modulates GATA-mediated Activation

1999 • 102 citations

Combinatorial interactions of Serpent, Lozenge, and U-shaped regulate crystal cell lineage commitment during Drosophila hematopoiesis

2003 • 101 citations

Distinct Domains of the GATA-1 Cofactor FOG-1 Differentially Influence Erythroid versus Megakaryocytic Maturation

2002 • 96 citations

FOG acts as a repressor of red blood cell development inXenopus

2000 • 95 citations

Friend of GATA-1 Represses GATA-3–dependent Activity in CD4+ T Cells

2001 • 86 citations

The Caenorhabditis elegans gene sem-4 controls neuronal and mesodermal cell development and encodes a zinc finger protein.

1996 • 75 citations

Isolation and characterization of AINT: a novel ARNT interacting protein expressed during murine embryonic development

2000 • 75 citations

Transforming Acidic Coiled-coil Protein 3 (TACC3) Controls Friend of GATA-1 (FOG-1) Subcellular Localization and Regulates the Association between GATA-1 and FOG-1 during Hematopoiesis

2004 • 66 citations

Interaction between FOG-1 and the Corepressor C-Terminal Binding Protein Is Dispensable for Normal Erythropoiesis In Vivo

2002 • 63 citations

TACC3 expression is tightly regulated during early differentiation

2003 • 54 citations

The solution structure of the N-terminal zinc finger of GATA-1 reveals a specific binding face for the transcriptional co-factor FOG.

1999 • 52 citations

Solution Structures of Two CCHC Zinc Fingers from the FOG Family Protein U-Shaped that Mediate Protein–Protein Interactions

2000 • 47 citations

GATA-1- and FOG-dependent Activation of Megakaryocytic αIIB Gene Expression

2000 • 39 citations

FOG-2 Competes with GATA-4 for Transcriptional Coactivator p300 and Represses Hypertrophic Responses in Cardiac Myocytes

2004 • 39 citations

Characterization and localization of expression of an erythropoietin‐induced gene, ERIC‐1/TACC3, identified in erythroid precursor cells

2001 • 34 citations

A Classic Zinc Finger from Friend of GATA Mediates an Interaction with the Coiled-coil of Transforming Acidic Coiled-coil 3

2004 • 31 citations

Molecular cloning and characterization of the GATA1 cofactor human FOG1 and assessment of its binding to GATA1 proteins carrying D218 substitutions

2003 • 31 citations

The use of altered specificity mutants to probe specific protein–protein interactions involved in the activation of GATA-1 target genes

2002 • 29 citations