The proline-rich region of the GH receptor is essential for JAK2 phosphorylation, activation of cell proliferation, and gene transcription.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Growth hormone receptor and serum binding protein: purification, cloning and expression

1987 • 1,540 citations

Structural basis for the binding of proline-rich peptides to SH3 domains

1994 • 1,016 citations

Jaks and Stats in signaling by the cytokine receptor superfamily

1995 • 902 citations

Two Binding Orientations for Peptides to the Src SH3 Domain: Development of a General Model for SH3-Ligand Interactions

1994 • 800 citations

IL3-dependent mouse clones that express B-220 surface antigen, contain ig genes in germ-line configuration, and generate B lymphocytes in vivo

1985 • 718 citations

Rational Design of Potent Antagonists to the Human Growth Hormone Receptor

1992 • 633 citations

A novel family of growth factor receptors: A common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor β-chain

1989 • 551 citations

The Conserved Box 1 Motif of Cytokine Receptors Is Required for Association with JAK Kinases

1995 • 249 citations

Proline-rich Sequence-mediated Jak2 Association to the Prolactin Receptor Is Required but Not Sufficient for Signal Transduction

1995 • 172 citations

Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase.

1994 • 171 citations

Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase.

1994 • 127 citations

Mutational analysis of the intracellular domain of the human growth hormone receptor

1993 • 120 citations

Growth Hormone (GH) Stimulates Protein Synthesis in Cells Transfected with GH Receptor Complementary DNA

1990 • 56 citations