High levels of type VII collagen expression in recessive dystrophic epidermolysis bullosa cutaneous squamous cell carcinoma keratinocytes increases PI3K and MAPK signalling, cell migration and invasion

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

1990 • 2,129 citations

Episomal Vectors Rapidly and Stably Produce High-Titer Recombinant Retrovirus

1996 • 768 citations

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1991 • 592 citations

Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma

2011 • 435 citations

Epidermolysis bullosa and the risk of life-threatening cancers: The National EB Registry experience, 1986-2006

2008 • 380 citations

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2010 • 355 citations

Temporal Dissection of Tumorigenesis in Primary Cancers

2011 • 269 citations

Type VII Collagen, Anchoring Fibrils, and Epidermolysis Bullosa

1993 • 266 citations

Stable nonviral genetic correction of inherited human skin disease

2002 • 249 citations

Potential of Fibroblast Cell Therapy for Recessive Dystrophic Epidermolysis Bullosa

2008 • 242 citations

A missense mutation in type VII collagen in two affected siblings with recessive dystrophic epidermolysis bullosa

1993 • 199 citations

Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa

2002 • 195 citations

Interactions of the Amino-terminal Noncollagenous (NC1) Domain of Type VII Collagen with Extracellular Matrix Components

1997 • 171 citations

Development of a quantitative method to analyse tumour cell invasion in organotypic culture

2005 • 145 citations

Type VII Collagen Is Required for Ras-Driven Human Epidermal Tumorigenesis

2005 • 141 citations

Injection of recombinant human type VII collagen restores collagen function in dystrophic epidermolysis bullosa

2004 • 135 citations

Injection of Recombinant Human Type VII Collagen Corrects the Disease Phenotype in a Murine Model of Dystrophic Epidermolysis Bullosa

2008 • 134 citations

Fibroblast-Derived Dermal Matrix Drives Development of Aggressive Cutaneous Squamous Cell Carcinoma in Patients with Recessive Dystrophic Epidermolysis Bullosa

2012 • 116 citations

Mechanisms of Fibroblast Cell Therapy for Dystrophic Epidermolysis Bullosa: High Stability of Collagen VII Favors Long-term Skin Integrity

2009 • 114 citations

Increased invasive behaviour in cutaneous squamous cell carcinoma with loss of basement-membrane type VII collagen

2009 • 108 citations

SIN Retroviral Vectors Expressing COL7A1 Under Human Promoters for Ex Vivo Gene Therapy of Recessive Dystrophic Epidermolysis Bullosa

2010 • 104 citations

Distribution patterns of type VII collagen in normal and malignant human tissues.

1991 • 94 citations

Construction of Skin Equivalents for Gene Therapy of Recessive Dystrophic Epidermolysis Bullosa

2004 • 90 citations

Alpha 6 beta 4 integrin and newly deposited laminin-1 and laminin-5 form the adhesion mechanism of gastric carcinoma. Continuous expression of laminins but not that of collagen VII is preserved in invasive parts of the carcinomas: implications for acquisition of the invading phenotype.

1996 • 87 citations

Epidermolysis Bullosa Dystrophica With Epidermal Neoplasms

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Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma

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Novel Molecular Therapies for Heritable Skin Disorders

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A Laminin-Collagen Complex Drives Human Epidermal Carcinogenesis through Phosphoinositol-3-Kinase Activation

2007 • 58 citations

Patients with Recessive Dystrophic Epidermolysis Bullosa Develop Squamous-Cell Carcinoma Regardless of Type VII Collagen Expression

2007 • 57 citations

Co-expression of p16INK4A and Laminin 5 by Keratinocytes: A Wound-Healing Response Coupling Hypermotility with Growth Arrest that Goes Awry During Epithelial Neoplastic Progression

2005 • 32 citations

Fibronectin Expression Determines Skin Cell Motile Behavior

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Patterns and composition of basement membranes in colon adenomas and adenocarcinomas

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Collagen mRNA levels changes during colorectal cancer carcinogenesis

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Modified Basement Membrane Composition During Bronchopulmonary Tumor Progression

2000 • 24 citations

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