Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells

Multilineage Potential of Adult Human Mesenchymal Stem Cells

1999 • 20,447 citations

Human mesenchymal stem cells modulate allogeneic immune cell responses

2004 • 4,360 citations

Nitric oxide and the immune response

2001 • 3,222 citations

Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli

2002 • 3,149 citations

Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase–mediated tryptophan degradation

2004 • 1,621 citations

Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide

2003 • 1,597 citations

Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation

2003 • 1,505 citations

Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals

2003 • 1,167 citations

Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells

2005 • 1,128 citations

Rapid Hematopoietic Recovery After Coinfusion of Autologous-Blood Stem Cells and Culture-Expanded Marrow Mesenchymal Stem Cells in Advanced Breast Cancer Patients Receiving High-Dose Chemotherapy

2000 • 1,115 citations

Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness

2004 • 1,027 citations

Myeloid Suppressor Lines Inhibit T Cell Responses by an NO-Dependent Mechanism

2002 • 657 citations

Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction

2004 • 574 citations

Stat5 Is Required for IL-2-Induced Cell Cycle Progression of Peripheral T Cells

1999 • 554 citations

Mesenchymal stem cells promote engraftment of human umbilical cord blood–derived CD34+ cells in NOD/SCID mice

2002 • 494 citations

Macrophage-Derived Nitric Oxide Regulates T Cell Activation via Reversible Disruption of the Jak3/STAT5 Signaling Pathway

1998 • 473 citations

Inducible Nitric Oxide Synthase Binds, S-Nitrosylates, and Activates Cyclooxygenase-2

2005 • 469 citations

Murine marrow‐derived mesenchymal stem cell: isolation, in vitro expansion, and characterization

2003 • 458 citations

Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation

2004 • 451 citations

Nitric oxide production is required for murine resident peritoneal macrophages to suppress mitogen-stimulated T cell proliferation. Role of IFN-gamma in the induction of the nitric oxide-synthesizing pathway.

1991 • 384 citations

Human mesenchymal stem cells require monocyte-mediated activation to suppress alloreactive T cells

2005 • 375 citations

Homing of in vitro expanded Stro-1- or Stro-1+ human mesenchymal stem cells into the NOD/SCID mouse and their role in supporting human CD34 cell engraftment

2004 • 252 citations

Bone marrow–derived mesenchymal stem cells remain host-derived despite successful hematopoietic engraftment after allogeneic transplantation in patients with lysosomal and peroxisomal storage diseases

1999 • 242 citations

Nitric Oxide Synthase/COX Cross-Talk: Nitric Oxide Activates COX-1 But Inhibits COX-2-Derived Prostaglandin Production

2000 • 182 citations

Nitric oxide involvement in tumor-induced immunosuppression.

1994 • 171 citations

Nonexpanded primary lung and bone marrow–derived mesenchymal cells promote the engraftment of umbilical cord blood–derived CD34+ cells in NOD/SCID mice

2003 • 148 citations

Suppression of T cell proliferation by tumor-induced granulocyte-macrophage progenitor cells producing transforming growth factor-beta and nitric oxide.

1996 • 147 citations

Nitric oxide-producing CD11b+Ly-6G(Gr-1)+CD31(ER-MP12)+cells in the spleen of cyclophosphamide–treated mice: implications for T-cell responses in immunosuppressed mice

2000 • 139 citations

Peroxisomal localization of inducible nitric oxide synthase in hepatocytes

2002 • 121 citations

Genistein stimulates the osteoblastic differentiation via NO/cGMP in bone marrow culture

2004 • 106 citations

Nitric Oxide Mediation of Active Immunosuppression Associated With Graft-Versus-Host Reaction

1999 • 56 citations

Augmentation of an Antitumor CTL Response In Vivo by Inhibition of Suppressor Macrophage Nitric Oxide

1999 • 46 citations

Prostanoid pattern and iNOS expression during chondrogenic differentiation of human mesenchymal stem cells

2006 • 16 citations