Protein kinase C‐induced redistribution of the cytoskeleton and phosphorylation of vimentin in cultured brain macrophages

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Characterization of ameboid microglia isolated from developing mammalian brain

1986 • 1,287 citations

The Brain in AIDS: Central Nervous System HIV-1 Infection and AIDS Dementia Complex

1988 • 1,244 citations

Greenfield's Neuropathology

1985 • 1,149 citations

Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties.

1982 • 1,008 citations

Factors regulating macrophage production and growth. Purification and some properties of the colony stimulating factor from medium conditioned by mouse L cells.

1977 • 740 citations

Antigen presentation and tumor cytotoxicity by interferon‐γ‐treated microglial cells

1987 • 648 citations

10 nm filaments in normal and transformed cells

1978 • 449 citations

The mechanism of protein kinase C activation

1989 • 423 citations

Colony-stimulating factors as promoters of ameboid microglia

1988 • 323 citations

Lamin B constitutes an intermediate filament attachment site at the nuclear envelope.

1987 • 306 citations

A tumor promoter induces rapid and coordinated reorganization of actin and vinculin in cultured cells.

1984 • 303 citations

Brain macrophages synthesize interleukin‐1 and interleukin‐1 mRNAs in vitro

1988 • 286 citations

Modulation of protein kinase C and diverse cell functions by sphingosine — a pharmacologically interesting compound linking sphingolipids and signal transduction

1989 • 281 citations

Phorbol ester-induced activation of human platelets is associated with protein kinase C phosphorylation of myosin light chains

1983 • 265 citations

Intermediate filament proteins in nonfilamentous structures: Transient disintegration and inclusion of subunit proteins in granular aggregates

1982 • 250 citations

Brain macrophages: questions of origin and interrelationship

1988 • 220 citations

Lipopolysaccharide-free conditions in primary astrocyte cultures allow growth and isolation of microglial cells

1989 • 217 citations

Vinculin, a cytoskeletal substrate of protein kinase C.

1983 • 215 citations

The microglial cytoskeleton: vimentin is localized within activated cellsin situ

1988 • 183 citations

An alteration in the phosphorylation of vimentin-type intermediate filaments is associated with mitosis in cultured mammalian cells

1982 • 158 citations

Involvement of the n-terminal polypeptide of vimentin in the formation of intermediate filaments

1983 • 153 citations

Pharmacology of the isoquinoline sulfonamide protein kinase C inhibitors

1987 • 148 citations

Phosphorylation of cardiac troponin inhibitory subunit (troponin I) and tropomyosin-binding subunit (troponin T) by cardiac phospholipid-sensitive Ca2+-dependent protein kinase

1983 • 139 citations

Phorbol myristate acetate stimulates microtubule and 10-nm filament extension and lysosome redistribution in mouse macrophages.

1980 • 135 citations

General pathology of neurons and neuroglia

1992 • 134 citations

Modulation of vimentin containing intermediate filament distribution and phosphorylation in living fibroblasts by the cAMP-dependent protein kinase.

1989 • 134 citations

Intermediate Filaments in Nervous Tissue

1985 • 116 citations

Localization of newly synthesized vimentin subunits reveals a novel mechanism of intermediate filament assembly

1990 • 115 citations

Phosphorylation in vitro of vimentin by protein kinases A and C is restricted to the head domain

1989 • 99 citations

Vimentin filaments are assembled from a soluble precursor in avian erythroid cells.

1983 • 96 citations

In situ phosphorylation of human platelet myosin heavy and light chains by protein kinase C

1989 • 95 citations

Phosphorylation of the cytoskeletal protein talin by protein kinase C

1986 • 93 citations

Ca2+-Activated, phospholipid-dependent protein kinase catalyzes the phosphorylation of actin-binding proteins

1984 • 91 citations

Intermediate filaments

1989 • 75 citations

Phosphorylation of bovine platelet myosin by protein kinase C

1990 • 71 citations

Intermediate filaments: known structure, unknown function

1989 • 69 citations

The intermediate-filament proteins vimentin and desmin are phosphorylated in specific domains.

1988 • 68 citations

Keratin filament disruption in interphase and mitotic cells--how is it induced?

1987 • 67 citations

Immunophenotypic characterization of rat brain macrophages in culture

1989 • 60 citations

A reassessment of Guanine Nucleotide Effects on Catecholamine Secretion from Permeabilized Adrenal Chromaffin cells

1989 • 58 citations

Phosphorylation by protein kinase C of the 20,000-dalton light chain of myosin in intact and chemically skinned vascular smooth muscle.

1990 • 51 citations

The organization and solubility properties of intermediate filaments and microtubules of cortical astrocytes in culture

1986 • 50 citations

Phorbol ester‐induced change in astrocyte morphology: Correlation with protein kinase C activation and protein phosphorylation

1990 • 50 citations

Changes in protein phosphorylation during the cell cycle of Chinese hamster ovary cells.

1985 • 48 citations

Vimentin, a cytoskeletal substrate of protein kinase C

1988 • 48 citations

Cytoplasmic intermediate filament proteins and the nuclear lamins A, B and C share the IFA epitope

1987 • 45 citations

Fc AND C3 RECEPTORS

1981 • 41 citations

Neurofilament phosphorylation in peripheral nerve regeneration

1986 • 41 citations

Fibronectin and collagens modulate the proliferation and morphology of astroglial cells in culture

1987 • 39 citations

Evidence for coordinated phosphorylation of keratins and vimentin during mitosis in transformed human amnion cells

1983 • 38 citations

Regulation of assembly-disassembly of intermediate filaments in vitro.

1989 • 30 citations

Proteolytic degradation of vimentin and glial fibrillary acidic protein in rat astrocytes in primary culture

1984 • 30 citations

Effects of phorbol esters on cytoskeletal proteins in cultured bovine chromaffin cells: induction of neurofilament phosphorylation and reorganization of actin.

1990 • 29 citations

Mechanism of action of Clostridium difficile toxin B: role of external medium and cytoskeletal organization in intoxicated cells.

1989 • 29 citations

Protein Phosphorylation in Astrocytes Mediated by Protein Kinase C: Comparison with Phosphorylation by Cyclic AMP‐Dependent Protein Kinase

1989 • 27 citations

Regulation of RAW264 macrophage morphology and spreading: studies with protein kinase C activators, inhibitors and a cyclic AMP analog

1989 • 16 citations

Vimentin in human erythroleukemia (HEL) cells is modulated with differentiation inducers

1990 • 6 citations

Stimulation of protein phosphorylation in mixed glial cell primary cultures and subcultures by the phorbol ester 12-o-tetradecanoylphorbol-13-acetate (TPA)

1988 • 4 citations