A protein complex required for signal-sequence-specific sorting and translocation

Protein folding in the cell

1992 • 4,138 citations

MOLECULAR CHAPERONE FUNCTIONS OF HEAT-SHOCK PROTEINS

1993 • 1,591 citations

Intracellular protein topogenesis

1980 • 1,378 citations

Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components.

1975 • 1,175 citations

Protein translocation across the endoplasmic reticulum

1984 • 825 citations

[6] Preparation of microsomal membranes for cotranslational protein translocation

1983 • 679 citations

Translocation of proteins across the endoplasmic reticulum. I. Signal recognition protein (SRP) binds to in-vitro-assembled polysomes synthesizing secretory protein.

1981 • 644 citations

Large scale cDNA sequencing for analysis of quantitative and qualitative aspects of gene expression

1992 • 528 citations

NEW PHOTOLABELING AND CROSSLINKING METHODS

1993 • 446 citations

Protein translocation across the endoplasmic reticulum. I. Detection in the microsomal membrane of a receptor for the signal recognition particle.

1982 • 388 citations

Transport of Proteins Across the Endoplasmic Reticulum Membrane

1992 • 366 citations

Photocrosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particle.

1986 • 337 citations

The signal sequence of nascent preprolactin interacts with the 54K polypeptide of the signal recognition particle

1986 • 336 citations

CONTROLLED PROTEOLYSIS OF NASCENT POLYPEPTIDES IN RAT LIVER CELL FRACTIONS

1970 • 301 citations

A signal sequence receptor in the endoplasmic reticulum membrane

1987 • 291 citations

Partial resistance of nascent polypeptide chains to proteolytic digestion due to ribosomal shielding

1967 • 290 citations

A Tunnel in the Large Ribosomal Subunit Revealed by Three-Dimensional Image Reconstruction

1987 • 265 citations

A signal sequence is not required for protein export in prlA mutants of Escherichia coli.

1993 • 219 citations

Signal peptides open protein-conducting channels in E. coli

1992 • 216 citations

Bovine opsin has more than one signal sequence

1985 • 186 citations

Signal-sequence recognition by an Escherichia coli ribonucleoprotein complex

1992 • 184 citations

[53] Signal recognition particle: A ribonucleoprotein required for cotranslational translocation of proteins, isolation and properties

1983 • 155 citations

Nascent polypeptide chains emerge from the exit domain of the large ribosomal subunit: immune mapping of the nascent chain.

1982 • 142 citations

Direct probing of the interaction between the signal sequence of nascent preprolactin and the signal recognition particle by specific cross-linking.

1987 • 119 citations

Requirements for the membrane insertion of signal-anchor type proteins.

1991 • 83 citations

Protein translocation across the ER requires a functional GTP binding site in the alpha subunit of the signal recognition particle receptor.

1992 • 82 citations

Chapter 10 Transcription of Full-Length and Truncated mRNA Transcripts to Study Protein Translocation across the Endoplasmic Reticulum

1991 • 79 citations

Subcellular distribution of signal recognition particle and 7SL-RNA determined with polypeptide-specific antibodies and complementary DNA probe.

1983 • 77 citations

Genomic structure of the putative BTF3 transcription factor

1992 • 33 citations

Chapter 11 Probing the Molecular Environment of Translocating Polypeptide Chains by Cross-Linking

1991 • 31 citations