Conservation and reiteration of a kinase cascade

Raf-1 activates MAP kinase-kinase

1992 • 1,308 citations

An Osmosensing Signal Transduction Pathway in Yeast

1993 • 1,252 citations

Nuclear localization and regulation of erk- and rsk-encoded protein kinases.

1992 • 1,107 citations

A Divergence in the MAP Kinase Regulatory Network Defined by MEK Kinase and Raf

1993 • 1,086 citations

The Primary Structure of MEK, a Protein Kinase that Phosphorylates the ERK Gene Product

1992 • 931 citations

The complete DNA sequence of yeast chromosome III

1992 • 851 citations

Activation of Mitogen-Activated Protein Kinase Kinase by v-Raf in NIH 3T3 Cells and in Vitro

1992 • 691 citations

Mitogen-activated protein kinases: versatile transducers for cell signaling

1992 • 439 citations

The protein kinase homologue Ste20p is required to link the yeast pheromone response G-protein beta gamma subunits to downstream signalling components.

1992 • 427 citations

Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro.

1993 • 420 citations

A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C.

1993 • 373 citations

Fission yeast genes that confer resistance to staurosporine encode an AP-1-like transcription factor and a protein kinase related to the mammalian ERK1/MAP2 and budding yeast FUS3 and KSS1 kinases.

1991 • 369 citations

Raf functions downstream of Rasl in the Sevenless signal transduction pathway

1992 • 323 citations

Dominant Mutations in a Gene Encoding a Putative Protein Kinase (BCKT) Bypass the Requirement for a Saccharomyces cerevisiae Protein Kinase C Homolog

1992 • 322 citations

MKK1 and MKK2, Which Encode Saccharomyces cerevisiae Mitogen-Activated Protein Kinase-Kinase Homologs, Function in the Pathway Mediated by Protein Kinase C

1993 • 306 citations

Roles of glycerol and glycerol-3-phosphate dehydrogenase (NAD+) in acquired osmotolerance of Saccharomyces cerevisiae

1989 • 297 citations

Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1.

1992 • 292 citations

Constitutive mutants of the protein kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein.

1992 • 292 citations

FAR1 links the signal transduction pathway to the cell cycle machinery in yeast

1993 • 290 citations

C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation

1993 • 276 citations

A synthetic lethal screen identifies SLK1, a novel protein kinase homolog implicated in yeast cell morphogenesis and cell growth.

1992 • 235 citations

Xenopus MAP kinase activator is a serine/threonine/tyrosine kinase activated by threonine phosphorylation.

1992 • 232 citations

Signal Transduction During Pheromone Response in Yeast

1991 • 225 citations

PHEROMONE RESPONSE IN YEAST

1992 • 204 citations

A protein kinase gene complements the lytic phenotype of Saccharomyces cerevisiae lyt2 mutants

1991 • 197 citations

MAP kinase-related FUS3 from S. cerevisiae is activated by STE7 in vitro

1993 • 190 citations

Order of action of components in the yeast pheromone response pathway revealed with a dominant allele of the STE11 kinase and the multiple phosphorylation of the STE7 kinase.

1992 • 188 citations

MKK1 and MKK2, which encode Saccharomyces cerevisiae mitogen-activated protein kinase-kinase homologs, function in the pathway mediated by protein kinase C.

1993 • 187 citations

Dominant mutations in a gene encoding a putative protein kinase (BCK1) bypass the requirement for a Saccharomyces cerevisiae protein kinase C homolog.

1992 • 181 citations

Requirement of the Drosophila raf homologue for torso function

1989 • 181 citations

Functional homology of protein kinases required for sexual differentiation in Schizosaccharomyces pombe and Saccharomyces cerevisiae suggests a conserved signal transduction module in eukaryotic organisms.

1993 • 166 citations

The wis1 protein kinase is a dosage-dependent regulator of mitosis in Schizosaccharomyces pombe.

1991 • 133 citations

Erks: their fifteen minutes has arrived.

1992 • 133 citations

Immunological characterization of avian MAP kinases: evidence for nuclear localization.

1992 • 89 citations

A new protein kinase, SSP31, modulating the SMP3 gene-product involved in plasmid maintenance in Saccharomyces cerevisiae

1991 • 26 citations

Mutations in a Saccharomyces cerevisme host showing increased holding stability of the heterologous plasmid pSRI

1991 • 25 citations