Glia: the fulcrum of brain diseases

Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo

2005 • 5,087 citations

Microglia: a sensor for pathological events in the CNS

1996 • 4,309 citations

Glutamate uptake

2001 • 3,867 citations

ATP mediates rapid microglial response to local brain injury in vivo

2005 • 3,543 citations

Analysis of Fractalkine Receptor CX₃CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion

2000 • 2,356 citations

Histologie du système nerveux de l'homme & des vertébrés

1909 • 2,282 citations

Astrocytes, from brain glue to communication elements: the revolution continues

2005 • 1,689 citations

Astrocyte activation and reactive gliosis

2005 • 1,513 citations

Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation

2002 • 1,399 citations

The P2Y12 receptor regulates microglial activation by extracellular nucleotides

2006 • 1,349 citations

Astrocyte Control of Synaptic Transmission and Neurovascular Coupling

2006 • 1,266 citations

Müller cells in the healthy and diseased retina

2006 • 1,034 citations

Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization.

1995 • 1,021 citations

Potassium buffering in the central nervous system

2004 • 787 citations

Histologie du Système Nerveux de Lʼhomme et des Vertébrés

1998 • 704 citations

Astrocytic complexity distinguishes the human brain

2006 • 672 citations

Neuron–glia metabolic coupling and plasticity

2006 • 648 citations

Microstructure of the neocortex: comparative aspects.

2002 • 635 citations

The neurobiology of glia in the context of water and ion homeostasis

2004 • 587 citations

Calcium-Mediated Mechanisms in Chemically Induced Cell Death

1992 • 518 citations

Multiple sclerosis: Altered glutamate homeostasis in lesions correlates with oligodendrocyte and axonal damage

2001 • 461 citations

Evidence of elevated glutamate in multiple sclerosis using magnetic resonance spectroscopy at 3 T

2005 • 444 citations

Microglial phenotype: is the commitment reversible?

2006 • 421 citations

Proliferative Vitreoretinopathy

1998 • 374 citations

Control of gap-junctional communication in astrocytic networks

1996 • 374 citations

Update on connexins and gap junctions in neurons and glia in the mammalian nervous system

2004 • 365 citations

Hypoxic Induction of Endothelial Cell Growth Factors in Retinal Cells: Identification and Characterization of Vascular Endothelial Growth Factor (VEGF) as the Mitogen

1995 • 357 citations

The link between excitotoxic oligodendroglial death and demyelinating diseases

2001 • 345 citations

Gap junctions and connexin expression in the normal and pathological central nervous system

2002 • 329 citations

Glutamate‐mediated glial injury: Mechanisms and clinical importance

2005 • 325 citations

Evolution of increased glia–neuron ratios in the human frontal cortex

2006 • 322 citations

Functional connexin “hemichannels”: A critical appraisal

2006 • 319 citations

Role of glial cells in cerebral ischemia

2005 • 283 citations

Pathomechanisms of Cystoid Macular Edema

2004 • 265 citations

Regional specialization of retinal glial cell membrane

1984 • 264 citations

NMDA Receptors in Glia

2007 • 252 citations

Functional Specialization and Topographic Segregation of Hippocampal Astrocytes

1998 • 240 citations

Role of connexin-based gap junction channels and hemichannels in ischemia-induced cell death in nervous tissue

2004 • 232 citations

Novel Role of Vitamin K in Preventing Oxidative Injury to Developing Oligodendrocytes and Neurons

2003 • 225 citations

Microglia at brain stab wounds express connexin 43 andin vitroform functional gap junctions after treatment with interferon-γ and tumor necrosis factor-α

2001 • 218 citations

Kir potassium channel subunit expression in retinal glial cells: Implications for spatial potassium buffering†

2002 • 209 citations

Selective Glial Vulnerability following Transient Global Ischemia in Rat Brain

1998 • 206 citations

Connexin26 in adult rodent central nervous system: Demonstration at astrocytic gap junctions and colocalization with connexin30 and connexin43

2001 • 204 citations

Neuroprotection by tetracyclines

2004 • 203 citations

Emerging complexities in identity and function of glial connexins

2005 • 198 citations

Emerging concepts in periventricular white matter injury

2004 • 192 citations

IL-1β differentially regulates calcium wave propagation between primary human fetal astrocytes via pathways involving P2 receptors and gap junction channels

1999 • 182 citations

Four Classes of Intercellular Channels between Glial Cells in the CNS

2004 • 168 citations

Purinergic signaling and microglia

2006 • 167 citations

Characterization of cytokine responses to retinal detachment in rats.

2006 • 156 citations

Grid‐mapped freeze‐fracture analysis of gap junctions in gray and white matter of adult rat central nervous system, with evidence for a “panglial syncytium” that is not coupled to neurons

1997 • 151 citations

Grid-mapped freeze-fracture analysis of gap junctions in gray and white matter of adult rat central nervous system, with evidence for a ?panglial syncytium? that is not coupled to neurons

1997 • 145 citations

Increased expression and function of glutamate transporters in multiple sclerosis

2005 • 142 citations

Mechanisms of C5a and C3a Complement Fragment-Induced [Ca²⁺]_iSignaling in Mouse Microglia

1997 • 140 citations

In VitroIschemic Tolerance Involves Upregulation of Glutamate Transport Partly Mediated by the TACE/ADAM17-Tumor Necrosis Factor-α Pathway

2004 • 129 citations

Interlaminar astroglia of the cerebral cortex: a marker of the primate brain

2004 • 120 citations

Ischemic damage and subsequent proliferation of oligodendrocytes in focal cerebral ischemia

1997 • 116 citations

Excitotoxic oligodendrocyte death and axonal damage induced by glutamate transporter inhibition

2005 • 114 citations

Simultaneous neuroprotection and blockade of inflammation reverses autoimmune encephalomyelitis

2004 • 108 citations

Glucose metabolism and proliferation in glia: role of astrocytic gap junctions

2006 • 106 citations

Endothelins regulate astrocyte gap junctions in rat hippocampal slices

2004 • 105 citations

Activation of Kainate Receptors Sensitizes Oligodendrocytes to Complement Attack

2006 • 87 citations

Inhibition of M�ller cell glutamine synthetase rapidly impairs the retinal response to light

2000 • 86 citations

Reversal or reduction of glutamate and GABA transport in CNS pathology and therapy

2004 • 82 citations

Oligodendrocyte NMDA receptors: a novel therapeutic target

2006 • 79 citations

Effects of cytokines on microglial phenotypes and astroglial coupling in an inflammatory coculture model

2005 • 77 citations

Homotypic and Heterotypic Coupling Mediated by Gap Junctions During Glial Cell Differentiation In Vitro

1995 • 76 citations

Gap Junctions and Neuronal Injury: Protectants or Executioners?

2003 • 75 citations

Electrophysiology of rabbit Müller (glial) cells in experimental retinal detachment and PVR.

2001 • 75 citations

Calcium and glial cell death

2005 • 75 citations

Nitric Oxide Synthase Expression in Ischemic Rat Retinas

2000 • 61 citations

A reporter allele for investigating connexin 26 gene expression in the mouse brain

2003 • 61 citations

Biologische Untersuchungen,

1881 • 60 citations

Altered membrane physiology in Müller glial cells after transient ischemia of the rat retina

2004 • 59 citations

Calcium ions and integration in neural circuits

2006 • 54 citations

Altered Expression of the Glutamate Transporter EAAC1 in Neurons and Immature Oligodendrocytes after Transient Forebrain Ischemia

2000 • 54 citations

Kinetics of endothelin‐induced inhibition and glucose permeability of astrocyte gap junctions

2006 • 40 citations

Connexins and Information Transfer Through Glia

1999 • 32 citations

Glutamate receptors and excitotoxicity.

1993 • 23 citations