5-HT1B receptor knockout mice show no adaptive changes in 5-HT1A receptor function as measured telemetrically on body temperature and heart rate responses

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Enhanced Aggressive Behavior in Mice Lacking 5-HT _1B Receptor

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Identity of inhibitory presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites

1986 • 686 citations

A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635

1995 • 610 citations

Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist

1995 • 515 citations

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The mouse 5-hydroxytryptamine 1B receptor is localized predominantly on axon terminals

1994 • 346 citations

Localization of 5-HT1B, 5-HT1Dα, 5-HT1E and 5-HT1F receptor messenger RNA in rodent and primate brain

1994 • 343 citations

Alignment of receptor nomenclature with the human genome: classification of 5-HT1B and 5-HT1D receptor subtypes

1996 • 285 citations

Altered Emotional States in Knockout Mice Lacking 5-HT1A or 5-HT1B Receptors

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The pharmacology of the hypothermic response in mice to 8-hydroxy-2-(DI-n-propylamino)tetralin (8-OH-DPAT)

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Insights into the Neurobiology of Impulsive Behavior from Serotonin Receptor Knockout Mice

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WAY100135: a novel, selective antagonist at presynaptic and postsynaptic 5-HT1A receptors

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Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers.

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Cellular and subcellular localization of 5-hydroxytryptamine1B receptors in the rat central nervous system: immunocytochemical, autoradiographic and lesion studies

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Stress-Induced Hyperthermia in Singly Housed Mice

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Distribution of Serotonin Receptors

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Direct evidence for an important species difference in the mechanism of 8‐OH‐DPAT‐induced hypothermia

1991 • 174 citations

Key Role of 5-HT_1BReceptors in the Regulation of Paradoxical Sleep as Evidenced in 5-HT_1BKnock-Out Mice

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Anxiety, motor activation, and maternal-infant interactions in 5HT-sub(1B ) knockout mice.

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A model to measure anticipatory anxiety in mice?

1989 • 152 citations

Classification and nomenclature of 5-HT receptors: a comment on current issues

1995 • 150 citations

Absence of 5-HT1B receptors is associated with impaired impulse control in male 5-HT1B knockout mice

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Differential Actions of Serotonin, Mediated by 5-HT_1Band 5-HT_2CReceptors, on GABA-Mediated Synaptic Input to Rat Substantia Nigra Pars Reticulata NeuronsIn Vitro

1996 • 143 citations

Serotonin autoreceptor in rat hippocampus: Pharmacological characterization as a subtype of the 5-HT1 receptor

1986 • 136 citations

Are postsynaptic 5-HT1A receptors involved in the anxiolytic effects of 5-HT1A receptor agonists and in their inhibitory effects on the firing of serotonergic neurons in the rat?

1995 • 132 citations

Conditioned ultrasonic distress vocalizations in adult male rats as a behavioural paradigm for screening anti-panic drugs

1995 • 121 citations

Pharmacological validation of a novel animal model of anticipatory anxiety in mice

1990 • 120 citations

Serotonin 1B receptor modulation of startle reactivity, habituation, and prepulse inhibition in wild-type and serotonin 1B knockout mice

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Characterization of 8‐OH‐DPAT‐induced hypothermia in mice as a 5‐HT_1A autoreceptor response and its evaluation as a model to selectively identify antidepressants

1992 • 118 citations

Stress-induced hyperthermia as a putative anxiety model

1995 • 112 citations

Serotonin1A Receptor Activation by Flesinoxan in Humans Body Temperature and Neuroendocrine Responses

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Stress-induced hyperthermia in mice: Hormonal correlates

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Flesinoxan lowers blood pressure and heart rate in cats via 5-HT1A receptors

1988 • 83 citations

Modulation of dopamine release in the nucleus accumbens by 5-HT1B agonists: involvement of the hippocampo-accumbens pathway

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5‐HT Receptor Knockout Mice: Pharmacological Tools or Models of Psychiatric Disorders

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Effect of serotoninergic drugs on stress-induced hyperthermia (SIH) in mice

1990 • 56 citations

Downregulation of muscarinic- and 5-HT1B-mediated modulation of [3H]acetylcholine release in hippocampal slices of rats with fimbria-fornix lesions and intrahippocampal grafts of septal origin

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Stress-induced hyperthermia in mice: effects of flesinoxan on heart rate and body temperature

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Effects of glucocorticoids on 5-HT1A presynaptic function in the mouse

1994 • 52 citations

Effects of buspirone on plasma neurotransmitters in healthy subjects

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Complex effects of age and gender on hypothermic, adrenocorticotrophic hormone and cortisol responses to ipsapirone challenge in normal subjects

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Anxiolytic effects of flesinoxan in the stress-induced hyperthermia paradigm in singly-housed mice are 5-HT1A receptor mediated

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Development of 5-HT1A receptor antagonists

1995 • 40 citations

The effect of ipsapirone on behavioral and cardiac responses in the shock-probe/defensive burying test in male rats

1990 • 39 citations

Neuroendocrine effects of diazepam and flesinoxan in the stress-induced hyperthermia test in mice

1996 • 38 citations

Comparison of the cardiovascular effects of the 5-HT1A receptor agonist flesinoxan with that of 8-OH-DPAT in the rat

1990 • 38 citations

The anxiolytic effects of flesinoxan, a 5-HT1A receptor agonist, are not related to its neuroendocrine effects

1995 • 33 citations

Subcellular localization of 5-HT1B binding sites in the stratum griseum superficiale of the rat superior colliculus: An electron microscopic quantitative autoradiographic study

1996 • 31 citations

A comparison of the neuro‐endocrinological and temperature effects of DU 29894, flesinoxan, sulpiride and haloperidol in normal volunteers.

1995 • 30 citations

The effects of 5-HT 1A receptor agonists, 5-HT 1A receptor antagonists and their interaction on the fear-potentiated startle response

1998 • 30 citations

Cortisol, Hypothermic, and Behavioral Responses to Ipsapirone in Patients with Bipolar Depression and Normal Controls

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Corticosterone responses in 5-HT1B receptor knockout mice to stress or 5-HT1A receptor activation are normal

2000 • 27 citations

Stress‐Induced Hyperthermia in Mice

1995 • 26 citations

Effects of 5-HT1A receptor ligands in a modified Geller-Seifter conflict model in the rat

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p-Chlorophenylalanine attenuates the pituitary-adrenocorticol response to 5-HT1A receptor agonists in mice

1990 • 25 citations

8‐OH‐DPAT, flesinoxan and guanfacine: systemic and regional haemodynamic effects of centrally acting antihypertensive agents in anaesthetized rabbits

1989 • 19 citations

Systemic and Regional Hemodynamic Effects of the Putative 5-HT1AReceptor Agonist Flesinoxan in the Cat

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Cardiovascular activation by serotonergic stimulation: role of corticotropin-releasing factor

1994 • 14 citations

5-HT receptor knockouts: Constitutive, inducible or tissue-specific

1995 • 6 citations

Differential cardiovascular effects of 8‐hydroxy‐2‐(di‐n‐propylamino) tetralin (8‐OH‐DPAT), flesinoxan, 5‐methyl‐urapidil and MDL 75,608A in conscious spontaneously hypertensive rats

1993 • 5 citations

Are the cardiovascular effects and ‘5-HT syndrome’ induced by MDL 73,975 and flesinoxan in the dog mediated by 5-HT1A receptors?

1994 • 5 citations

Renal functional responses to the 5-HT1A receptor agonist flesinoxan: effects of controlled renal perfusion pressure.

1994 • 4 citations