Cyclic Nucleotide‐Gated Channels: Molecular Mechanisms of Activation

The L-Arginine-Nitric Oxide Pathway

1993 • 6,737 citations

Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle

1994 • 1,704 citations

Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segment

1985 • 1,213 citations

A cyclic nucleotide-gated conductance in olfactory receptor cilia

1987 • 1,134 citations

Activation of the Cardiac Calcium Release Channel (Ryanodine Receptor) by Poly-S-Nitrosylation

1998 • 983 citations

An essential role for free radicals and derived species in signal transduction

1997 • 909 citations

Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex

1992 • 737 citations

Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel

1989 • 663 citations

Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons

1990 • 650 citations

Non‐selective conductance in calcium channels of frog muscle: calcium selectivity in a single‐file pore.

1984 • 643 citations

Structure and Function of Cyclic Nucleotide-Gated Channels

1996 • 499 citations

A Putative Cyclic Nucleotide–Gated Channel Is Required for Sensory Development and Function in C. elegans

1996 • 439 citations

Cyclic Nucleotide-Gated Ion Channels: An Extended Family With Diverse Functions

1996 • 305 citations

NO, nitrosonium ions, nitroxide ions, nitrosothiols and iron-nitrosyls in biology: a chemist's perspective

1995 • 301 citations

Discrimination of molecular signals by the olfactory receptor neuron

1994 • 293 citations

A second subunit of the olfactory cyclic nucleotide-gated channel confers high sensitivity to cAMP

1994 • 273 citations

Heteromeric olfactory cyclic nucleotide-gated channels: a subunit that confers increased sensitivity to cAMP.

1994 • 259 citations

Molecular mechanism of cyclic-nucleotide-gated channel activation

1994 • 243 citations

The cyclic nucleotide-gated channels of vertebrate photoreceptors and olfactory epithelium

1991 • 224 citations

Identification of an external divalent cation-binding site in the pore of a cGMP-activated channel

1993 • 220 citations

Cyclic Nucleotide-Gated Ion Channels and Sensory Transduction in Olfactory Receptor Neurons

1994 • 190 citations

Molecular mechanism for ligand discrimination of cyclic nucleotide-gated channels

1995 • 183 citations

Single cyclic nucleotide-gated channels locked in different ligand-bound states

1997 • 170 citations

Subunit Stoichiometry of Cyclic Nucleotide-Gated Channels and Effects of Subunit Order on Channel Function

1996 • 166 citations

Direct Activation of the Olfactory Cyclic Nucleotide–Gated Channel through Modification of Sulfhydryl Groups by NO Compounds

1996 • 165 citations

Role of H5 domain in determining pore diameter and ion permeation through cyclic nucleotide-gated channels

1993 • 161 citations

Two Identical Noninteracting Sites in an Ion Channel Revealed by Proton Transfer

1994 • 160 citations

Localization of regions affecting an allosteric transition in cyclic nucleotide-activated channels

1995 • 159 citations

Nitric Oxide as an Autocrine Regulator of Sodium Currents in Baroreceptor Neurons

1998 • 141 citations

A histidine residue associated with the gate of the cyclic nucleotide-activated channels in rod photoreceptors

1995 • 141 citations

Functional Expression of the Heteromeric “Olfactory” Cyclic Nucleotide-Gated Channel in the Hippocampus: A Potential Effector of Synaptic Plasticity in Brain Neurons

1997 • 137 citations

Constraining Ligand-Binding Site Stoichiometry Suggests that a Cyclic Nucleotide–Gated Channel Is Composed of Two Functional Dimers

1998 • 136 citations

Exposure of Residues in the Cyclic Nucleotide–Gated Channel Pore: P Region Structure and Function in Gating

1996 • 118 citations

An isoform of the rod photoreceptor cyclic nucleotide-gated channel β subunit expressed in olfactory neurons

1998 • 110 citations

Cyclic nucleotide gated channels as regulators of CNS development and plasticity

1997 • 110 citations

Cyclic nucleotide-gated channels: an expanding new family of ion channels.

1994 • 108 citations

Calmodulin controls the rod photoreceptor CNG channel through an unconventional binding site in the N-terminus of the beta -subunit

1998 • 108 citations

Rat hippocampal neurons express genes for both rod retinal and olfactory cyclic nucleotide-gated channels: novel targets for cAMP/cGMP function.

1996 • 105 citations

Identification of a Domain on the β-Subunit of the Rod cGMP-gated Cation Channel That Mediates Inhibition by Calcium-Calmodulin

1998 • 103 citations

Molecular model of the cyclic GMP-binding domain of the cyclic GMP-gated ion channel

1992 • 92 citations

Direct Interaction between Amino- and Carboxyl-Terminal Domains of Cyclic Nucleotide-Gated Channels

1997 • 88 citations

Molecular and pharmacological analysis of cyclic nucleotide-gated channel function in the central nervous system

1998 • 82 citations

β Subunits of the Olfactory Cyclic Nucleotide-Gated Channel Form a Nitric Oxide Activated Ca2+ Channel

1997 • 82 citations

Three amino acids in the C-linker are major determinants of gating in cyclic nucleotide-gated channels

1998 • 77 citations

Subunit interactions in the activation of cyclic nucleotide-gated ion channels

1996 • 77 citations

Calmodulin regulation of cyclic-nucleotide-gated channels

1996 • 70 citations

Single-channel properties of ionic channels gated by cyclic nucleotides

1997 • 54 citations

Divalent Cation Selectivity in a Cyclic Nucleotide-Gated Ion Channel

1995 • 53 citations

Phosphorylation of Mammalian Olfactory Cyclic Nucleotide-Gated Channels Increases Ligand Sensitivity

1998 • 53 citations

Movement of Gating Machinery during the Activation of Rod Cyclic Nucleotide-Gated Channels

1998 • 46 citations

Ion selectivity predictions from a two-site permeation model for the cyclic nucleotide-gated channel of retinal rod cells

1997 • 22 citations

Cyclic Nucleotide-Gated Cation Channels

1996 • 21 citations

Mechanisms of modulation by internal protons of cyclic nucleotide–gated channels cloned from sensory receptor cells

1997 • 17 citations

Concentration Dependence of Sodium Permeation and Sodium Ion Interactions in the Cyclic AMP-gated Channels of Mammalian Olfactory Receptor Neurons

1997 • 9 citations