Direct Activation of the Olfactory Cyclic Nucleotide–Gated Channel through Modification of Sulfhydryl Groups by NO Compounds

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

Biochemistry of Nitric Oxide and Its Redox-Activated Forms

1992 • 2,725 citations

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds

1993 • 2,423 citations

Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle

1994 • 1,704 citations

S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds.

1992 • 1,454 citations

Biosynthesis and Metabolism of Endothelium-Derived Nitric Oxide

1990 • 1,284 citations

Nitric Oxide: First in a New Class of Neurotransmitters

1992 • 1,001 citations

Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex

1992 • 737 citations

Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel

1989 • 663 citations

Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons

1990 • 650 citations

Cloning and functional expression of a cyclic-nucleotide-gated channel from mammalian sperm

1994 • 312 citations

NO, nitrosonium ions, nitroxide ions, nitrosothiols and iron-nitrosyls in biology: a chemist's perspective

1995 • 301 citations

Spectrophotometric assay of thiols

1987 • 301 citations

Discrimination of molecular signals by the olfactory receptor neuron

1994 • 293 citations

Oxidation of thiols by nitric oxide and nitrogen dioxide: synthetic utility and toxicological implications

1982 • 288 citations

Profoundly different calcium permeation and blockage determine the specific function of distinct cyclic nucleotide-gated channels

1995 • 271 citations

Molecular cloning and single-channel properties of the cyclic nucleotide-gated channel from catfish olfactory neurons

1992 • 264 citations

Primary structure of cAMP‐gated channel from bovine olfactory epithelium

1990 • 260 citations

Mechanisms of Nitrogen Dioxide Reactions: Initiation of Lipid Peroxidation and the Production of Nitrous Acid

1981 • 256 citations

Implications of the NO/cGMP system for olfaction

1993 • 245 citations

Molecular mechanism of cyclic-nucleotide-gated channel activation

1994 • 243 citations

Nitric oxide mediates the formation of synaptic connections in developing and regenerating olfactory receptor neurons

1994 • 238 citations

cGMP-gated conductance in retinal bipolar cells is suppressed by the photoreceptor transmitter

1991 • 194 citations

Another member of the cyclic nucleotide-gated channel family, expressed in testis, kidney, and heart.

1994 • 180 citations

[40] Novel sulfhydryl reagents

1977 • 179 citations

A mechanistic and kinetic analysis of the interactions of the diastereoisomers of adenosine 3′,5′-(cyclic)phosphorothioate with purified cyclic AMP-dependent protein kinase

1988 • 171 citations

Two Identical Noninteracting Sites in an Ion Channel Revealed by Proton Transfer

1994 • 160 citations

Localization of regions affecting an allosteric transition in cyclic nucleotide-activated channels

1995 • 159 citations

A cyclic GMP-activated channel in dissociated cells of the chick pineal gland

1991 • 149 citations

A histidine residue associated with the gate of the cyclic nucleotide-activated channels in rod photoreceptors

1995 • 141 citations

Time course of the membrane current underlying sensory transduction in salamander olfactory receptor neurones.

1990 • 138 citations

Actions of redox-related congeners of nitric oxide at the NMDA receptor

1994 • 130 citations

A cyclic–nucleotide–suppressible conductance activated by transducin in taste cells

1995 • 121 citations

Chemical reduction of disulfides

1987 • 114 citations

Cyclic nucleotide-gated channels: an expanding new family of ion channels.

1994 • 108 citations

Divalent cations block the cyclic nucleotide-gated channel of olfactory receptor neurons

1993 • 106 citations

Analysis of single cyclic nucleotide-gated channels in olfactory receptor cells

1991 • 100 citations

A calcium-permeable cGMP-activated cation conductance in hippocampal neurons

1995 • 86 citations

Effects of nitric oxide upon olfactory receptor neurones in Xenopus laevis

1993 • 40 citations

NADPH-diaphorase localization in the olfactory system

1994 • 32 citations

[54] Reduction and reoxidation at disulfide bonds

1967 • 29 citations

The cyclic nucleotide gated channel of olfactory receptor neurons

1994 • 25 citations

[30] Reduction and reoxidation at disulfide bonds

1972 • 23 citations

Sulfhydryl binding reagents increase the conductivity of the light-sensitive channel and inhibit phototransduction in retinal rods

1990 • 16 citations