T-Cell Activation Is Potentiated by Cytokines Released by Lesional Psoriatic, but Not Normal, Epidermis

Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes.

1989 • 844 citations

Cyclosporine Improves Psoriasis in a Double-blind Study

1986 • 535 citations

Epidermal cell (keratinocyte)-derived thymocyte-activating factor (ETAF).

1981 • 420 citations

Human keratinocytes contain mRNA indistinguishable from monocyte interleukin 1 alpha and beta mRNA. Keratinocyte epidermal cell-derived thymocyte-activating factor is identical to interleukin 1.

1986 • 384 citations

cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium.

1991 • 326 citations

Acquired Immunodeficiency Syndrome— Associated Psoriasis and Reiter's Syndrome

1987 • 263 citations

Detection of a gamma interferon-induced protein IP-10 in psoriatic plaques.

1988 • 231 citations

Identification of C5ades arg and an Anionic Neutrophil-Activating Peptide (ANAP) in Psoriatic Scales

1986 • 230 citations

IFN-beta 2, B cell differentiation factor 2, or hybridoma growth factor (IL-6) is expressed and released by human epidermal cells and epidermoid carcinoma cell lines.

1989 • 205 citations

Expression of HLA-DR molecules by keratinocytes, and presence of Langerhans cells in the dermal infiltrate of active psoriatic plaques.

1986 • 196 citations

Role of the Microcirculation in the Treatment and Pathogenesis of Psoriasis

1982 • 193 citations

Psoriasis Induced at the Injection Site of Recombinant Interferon Gamma

1990 • 187 citations

Keratinocyte growth regulation by the products of immune cells.

1988 • 172 citations

Epidermal Keratiocytes Express the Adhesion Molecule Intercellular Adhesion Molecule-1 in Inflammatory Dermatoses.

1989 • 170 citations

Localization of Neutrophil-Activating Peptide-1/Interleukin-8-Immunoreactivity in Normal and Psoriatic Skin

1991 • 162 citations

The effects of cyclosporin A on T lymphocyte and dendritic cell sub-populations in psoriasis

1987 • 147 citations

IL-1 activity is reduced in psoriatic skin. Decreased IL-1 alpha and increased nonfunctional IL-1 beta.

1990 • 140 citations

Interleukin 1 binds to specific receptors on human keratinocytes and induces granulocyte macrophage colony-stimulating factor mRNA and protein. A potential autocrine role for interleukin 1 in epidermis.

1988 • 137 citations

Interleukin-1 receptor antagonist in normal and psoriatic epidermis.

1992 • 126 citations

The expression and modulation of IL-1 alpha in murine keratinocytes.

1988 • 123 citations

Proliferating Cells in Psoriatic Dermis Are Comprised Primarily of T Cells, Endothelial Cells, and Factor XIIIa+ Perivascular Dendritic Cells

1991 • 120 citations

Interleukin 2 and Psoriasis

1988 • 113 citations

Psoriatic Epidermal Cells Demonstrate Increased Numbers and Function of Non-Langerhans Antigen-presenting Cells

1989 • 105 citations

Keratinocyte Derived T-Cell Growth Factor (KTGF) Is Identical to Granulocyte Macrophage Colony Stimulating Factor (GM-CSF)

1988 • 102 citations

Interleukin-8 Immunoreactivity in the Skin of Healthy Subjects and Patients with Palmoplantar Pustulosis and Psoriasis

1992 • 101 citations

UM4D4+ (CDw60) T Cells Are Compartmentalized into Psoriatic Skin and Release Lymphokines That Induce a Keratinocyte Phenotype Expressed in Psoriatic Lesions

1990 • 95 citations

Remission of psoriatic lesions with muromonab-CD3 (Orthoclone OKT3) treatment

1989 • 81 citations

Mechanisms of Cyclosporine A Inhibition of Antigen-Presenting Activity in Uninvolved and Lesional Psoriatic Epidermis

1990 • 59 citations

Granulocyte-Macrophage Colony-Stimulating Factor in Psoriasis

1990 • 34 citations

Intralesional cyclosporine for psoriasis. Relationship of dose, tissue levels, and efficacy

1992 • 32 citations

Psoriatic skin reveals the in vivo presence of an epidermal IL-1 inhibitor

1992 • 7 citations