Genetic transformation of mycobacteria

New use of BCG for recombinant vaccines

1991 • 1,463 citations

Tuberculosis: Commentary on a Reemergent Killer

1992 • 1,400 citations

The catalase—peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis

1992 • 1,287 citations

Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis

1990 • 1,231 citations

An Outbreak of Tuberculosis with Accelerated Progression among Persons Infected with the Human Immunodeficiency Virus

1992 • 1,015 citations

Occurrence and stability of insertion sequences in Mycobacterium tuberculosis complex strains: evaluation of an insertion sequence-dependent DNA polymorphism as a tool in the epidemiology of tuberculosis

1991 • 996 citations

Tuberculosis: a global overview of the situation today.

1992 • 544 citations

Characterization of a Mycobacterium tuberculosis insertion sequence, IS6110, and its application in diagnosis

1990 • 483 citations

[25] Genetic systems for mycobacteria

1991 • 437 citations

Rapid Assessment of Drug Susceptibilities of Mycobacterium tuberculosis by Means of Luciferase Reporter Phages

1993 • 428 citations

Detection ofMycobacterium tuberculosisin Sputum Samples Using a Polymerase Chain Reaction

1991 • 364 citations

Humoral and cell-mediated immune responses to live recombinant BCG–HIV vaccines

1991 • 315 citations

Introduction of foreign DNA into mycobacteria using a shuttle phasmid

1987 • 312 citations

The mycobacteria: a sourcebook

1985 • 262 citations

Mycobacterial protein antigens: a compilation

1992 • 249 citations

Transposition of an antibiotic resistance element in mycobacteria

1990 • 230 citations

DNA sequence, structure and gene expression of mycobacteriophage L5: a phage system for mycobacterial genetics

1993 • 223 citations

Gene replacement and expression of foreign DNA in mycobacteria

1990 • 172 citations

Functional analysis of pAL5000, a plasmid from Mycobacterium fortuitum: construction of a "mini" mycobacterium-Escherichia coli shuttle vector

1990 • 167 citations

Superinfection immunity of mycobacteriophage L5: applications for genetic transformation of mycobacteria

1993 • 161 citations

MOLECULAR BIOLOGY OF THE MYCOBACTERIA

1989 • 145 citations

Transfer of plasmid RSF1010 by conjugation from Escherichia coli to Streptomyces lividans and Mycobacterium smegmatis

1991 • 129 citations

A novel transposon trap for mycobacteria: isolation and characterization of IS1096

1991 • 100 citations

Mycobacterium smegmatis RNA polymerase: DNA supercoiling, action of rifampicin and mechanism of rifampicin resistance

1993 • 95 citations

Expression of heterologous genes in Mycobacterium bovis BCG: induction of a cellular response against HIV-1 Nef protein

1991 • 89 citations

Transduction in Mycobacterium smegmatis

1970 • 76 citations

National action plan to combat multidrug-resistant tuberculosis.

1992 • 72 citations

Construction and characterization of a Mycobacterium-Escherichia coli shuttle vector

1991 • 71 citations

Temperature-sensitive mutants of the mycobacterium plasmid pAL5000

1992 • 59 citations

Leprosy, tuberculosis, and the new genetics

1993 • 55 citations

Isolation and analysis of IS6120, a new insertion sequence from Mycobacterium smegmatis

1992 • 51 citations

Identification of expression signals of the mycobacteriophages Bxb1, L1 and TM4 using the Escherichia-Mycobacterium shuttle plasmids pYUB75 and pYUB76 designed to create translational fusions to the lacZ gene

1992 • 50 citations

Transformation of Mycobacterium aurum and Mycobacterium smegmatis with the broad host‐range Gram‐negative cosmid vector pJRD215

1991 • 41 citations

Site-specific integration of the Streptomyces plasmid pSAM2 in Mycobacterium smegmatis

1991 • 41 citations

IS900‐promoted stable integration of a foreign gene into mycobacteria

1991 • 38 citations

Stable integration and expression of the Plasmodium falciparum circumsporozoite protein coding sequence in mycobacteria

1993 • 35 citations

Molecular biology of mycobacteria

1988 • 28 citations

Development of a new host vector system in mycobacteria

1991 • 26 citations

Transduction of Isoniazid Susceptibility-Resistance and Streptomycin Resistance in Mycobacteria

1973 • 19 citations

An Escherichia coli-Mycobacterium shuttle cosmid vector, pMSC1

1992 • 17 citations

Insertion into the Mycobacterium smegmatis genome of the aph gene through lysogenization with the temperate mycobacteriophage Ms6

1992 • 12 citations

Insertion into theMycobacterium smegmatisgenome of theaphgene through lysogenization with the temperate mycobacteriophage Ms6

1992 • 9 citations