Transcriptional activation by a DNA-tracking protein: Structural consequences of enhancement at the T4 late promoter

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1987 • 11,491 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

The sigma 70 family: sequence conservation and evolutionary relationships

1992 • 894 citations

Molecular Biology of Bacteriophage T4

1994 • 881 citations

Three-dimensional structure of the β subunit of E. coli DNA polymerase III holoenzyme: A sliding DNA clamp

1992 • 748 citations

Activators and targets

1990 • 582 citations

S. cerevisiae TFIIIB is the transcription initiation factor proper of RNA polymerase III, while TFIIIA and TFIIIC are assembly factors

1990 • 494 citations

Sigma factors fromE. coli, B. subtilis, phage SP01, and phage T4 are homologous proteins

1986 • 460 citations

Mechanism of the sliding beta-clamp of DNA polymerase III holoenzyme

1991 • 420 citations

Regulation of Gene Expression

1968 • 417 citations

Protein-protein communication within the transcription apparatus

1993 • 366 citations

Crystal structure of bacteriophage T7 RNA polymerase at 3.3 Å resolution

1993 • 358 citations

Transcription activation at Class I CAP‐dependent promoters

1993 • 350 citations

KMnO4 as a probe for lac promoter DNA melting and mechanism in vivo

1989 • 294 citations

DNA-looping and enhancer activity: association between DNA-bound NtrC activator and RNA polymerase at the bacterial glnA promoter.

1990 • 260 citations

Thymine glycols and urea residues in M13 DNA constitute replicative blocksin vitro

1985 • 258 citations

Sliding Clamps of DNA Polymerases

1993 • 250 citations

Defining a bacteriophage T4 late promoter: Absence of a “−35” region

1984 • 192 citations

A Bacterial Enhancer Functions to Tether a Transcriptional Activator Near a Promoter

1990 • 190 citations

The subunit structure of Saccharomyces cerevisiae transcription factor IIIC probed with a novel photocrosslinking reagent.

1990 • 176 citations

Two components of Saccharomyces cerevisiae transcription factor IIIB (TFIIIB) are stereospecifically located upstream of a tRNA gene and interact with the second-largest subunit of TFIIIC.

1991 • 160 citations

A Transcriptional Enhancer Whose Function Imposes a Requirement That Proteins Track Along DNA

1992 • 130 citations

Purification of the gene 43, 44, 45, and 62 proteins of the bacteriophage T4 DNA replication apparatus.

1979 • 124 citations

Transactivation of the Xenopus rRNA gene promoter by its enhancer

1989 • 108 citations

Enhancement of Bacteriophage T4 Late Transcription by Components of the T4 DNA Replication Apparatus

1989 • 107 citations

Structural and Enzymatic Studies of the T4 DNA Replication System

1989 • 86 citations

Protein-DNA cross-linking demonstrates stepwise ATP-dependent assembly of T4 DNA polymerase and its accessory proteins on the primer-template

1991 • 86 citations

An RNA Polymerase-Binding Protein That Is Required for Communication Between an Enhancer and a Promoter

1990 • 69 citations

Transcription at bacteriophage T4 variant late promoters. An application of a newly devised promoter-mapping method involving RNA chain retraction.

1986 • 67 citations

Assembly of a functional replication complex without ATP hydrolysis: a direct interaction of bacteriophage T4 gp45 with T4 DNA polymerase.

1993 • 54 citations

The T4 DNA polymerase accessory proteins form an ATP-dependent complex on a primer-template junction.

1991 • 48 citations

Analysis of a T4 DNA replication protein complex. Studies of the DNA recognition site for T4 gene 44/62 and 45 protein-catalyzed ATP hydrolysis.

1978 • 45 citations

Overproduced bacteriophage T4 gene 33 protein binds RNA polymerase

1989 • 32 citations

Interactions of the bacteriophage T4 gene 55 product with Escherichia coli RNA polymerase. Competition with Escherichia coli sigma 70 and release from late T4 transcription complexes following initiation.

1987 • 30 citations

Laser cross-linking of proteins to nucleic acids. II. Interactions of the bacteriophage T4 DNA replication polymerase accessory proteins complex with DNA

1993 • 26 citations

Molecular genetic analysis of a prokaryotic transcriptional coactivator: functional domains of the bacteriophage T4 gene 33 protein

1994 • 15 citations

Late sigma factor of bacteriophage T4. Formation and properties of RNA polymerase-promoter complexes.

1988 • 14 citations

Characteristic views of Escherichia coli RNA polymerase core enzyme in the scanning transmission electron microscope

1990 • 5 citations