The Saccharomyces retrotransposon Ty5 integrates preferentially into regions of silent chromatin at the telomeres and mating loci.

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Genetic applications of an inverse polymerase chain reaction.

1988 • 1,867 citations

Origin and evolution of retroelements based upon their reverse transcriptase sequences.

1990 • 1,351 citations

Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription

1990 • 1,343 citations

Telomere elongation in immortal human cells without detectable telomerase activity.

1995 • 1,249 citations

An alternative pathway for yeast telomere maintenance rescues est1− senescence

1993 • 916 citations

The complete DNA sequence of yeast chromosome III

1992 • 851 citations

Ty elements transpose through an RNA intermediate

1985 • 837 citations

Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: A molecular model for the formation of heterochromatin in yeast

1995 • 778 citations

Four Genes Responsible for a Position Effect on Expression From HML and HMR in Saccharomyces cerevisiae

1987 • 709 citations

Characterization of a “silencer” in yeast: A DNA sequence with properties opposite to those of a transcriptional enhancer

1985 • 531 citations

Binding and Stimulation of HIV-1 Integrase by a Human Homolog of Yeast Transcription Factor SNF5

1994 • 523 citations

A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation.

1992 • 480 citations

Extremely conserved histone H4 N terminus is dispensable for growth but essential for repressing the silent mating loci in yeast

1988 • 441 citations

Transposons in place of telomeric repeats at a Drosophila telomere

1993 • 436 citations

Yeast Origin Recognition Complex Functions in Transcription Silencing and DNA Replication

1993 • 435 citations

Analysis of subtelomeric heterochromatin in the Drosophila minichromosome Dp1187 by single P element insertional mutagenesis.

1992 • 403 citations

Identification and characterization of genes and mutants for an N-terminal acetyltransferase from yeast.

1989 • 325 citations

Origin Recognition Complex (ORC) in Transcriptional Silencing and DNA Replication in S. cerevisiae

1993 • 314 citations

Transposable elements are stable structural components of Drosophila melanogaster heterochromatin.

1995 • 309 citations

Complete Nucleotide Sequence of the Drosophila Transposable Element Copia: Homology Between Copia and Retroviral Proteins

1985 • 299 citations

Silencers, silencing, and heritable transcriptional states

1992 • 296 citations

Single-step selection for Ty1 element retrotransposition.

1991 • 260 citations

Addition of telomere-associated HeT DNA sequences “heals” broken chromosome ends in Drosophila

1990 • 245 citations

Purification of a yeast protein that binds to origins of DNA replication and a transcriptional silencer.

1988 • 234 citations

Silencers and Domains of Generalized Repression

1994 • 233 citations

Yeast origin recognition complex is involved in DNA replication and transcriptional silencing

1993 • 231 citations

Histone H3 amino terminus is required for telomeric and silent mating locus repression in yeast

1994 • 227 citations

Integration of the yeast retrotransposon Ty1 is targeted to regions upstream of genes transcribed by RNA polymerase III.

1996 • 221 citations

Hotspots for unselected Ty1 transposition events on yeast chromosome III are near tRNA genes and LTR sequences

1993 • 219 citations

The chromosome end in yeast: its mosaic nature and influence on recombinational dynamics.

1994 • 216 citations

Requirement of RNA Polymerase III Transcription Factors for in Vitro Position-Specific Integration of a Retroviruslike Element

1995 • 208 citations

Ty3 integrates within the region of RNA polymerase III transcription initiation.

1992 • 207 citations

A copia-like transposable element family in Arabidopsis thaliana

1988 • 192 citations

RAP1 protein activates and silences transcription of mating-type genes in yeast.

1991 • 170 citations

INTEGRATION SPECIFICITY OF RETROTRANSPOSONS AND RETROVIRUSES

1990 • 155 citations

Translational Suppression in Gene Expression in Retroviruses and Retrotransposons

1990 • 138 citations

Shrimp Pm-fortilin inhibits the expression of early and late genes of white spot syndrome virus (WSSV) in an insect cell model

2010 • 128 citations

tRNA genes as transcriptional repressor elements.

1994 • 127 citations

Two related families of retrotransposons from Schizosaccharomyces pombe.

1990 • 123 citations

Transfer RNA genes are genomic targets for de Novo transposition of the yeast retrotransposon Ty3.

1990 • 105 citations

Mating-type gene switching in Saccharomyces cerevisiae

1992 • 105 citations

Initiator methionine tRNA is essential for Ty1 transposition in yeast.

1992 • 96 citations

Chromatin-mediated transcription repression in yeast

1995 • 94 citations

Hotspots and warm spots: integration specificity of retroelements

1992 • 92 citations

Yeast retrotransposons and tRNAs

1993 • 92 citations

Efficient homologous recombination of Ty1 element cDNA when integration is blocked.

1994 • 91 citations

Unusual priming mechanism of RNA-directed DNA synthesis in copia retrovirus-like particles of Drosophila

1986 • 88 citations

Virus-like particle formation of Drosophila copia through autocatalytic processing.

1990 • 81 citations

Multiple Molecular Determinants for Retrotransposition in a Primer tRNA

1995 • 71 citations

The Saccharomyces Ty5 retrotransposon family is associated with origins of DNA replication at the telomeres and the silent mating locus HMR.

1995 • 64 citations

The Retrotransposon Tf1 Assembles Virus-Like Particles That Contain Excess Gag Relative to Integrase because of a Regulated Degradation Process

1996 • 50 citations

Multimeric arrays of the yeast retrotransposon Ty.

1990 • 38 citations

Telomere-mediated plasmid segregation in Saccharomyces cerevisiae involves gene products required for transcriptional repression at silencers and telomeres.

1993 • 27 citations