Compromised blood-nerve barrier, astrogliosis, and myelin disruption in optic nerves during fatal murine cerebral malaria

Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro

1988 • 1,371 citations

TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria

1990 • 861 citations

Tumor Necrosis Factor and Disease Severity in Children with Falciparum Malaria

1989 • 852 citations

Tumor Necrosis Factor (Cachectin) as an Essential Mediator in Murine Cerebral Malaria

1987 • 749 citations

Astrocyte Responses to CNS Injury

1994 • 596 citations

Anti—tumor necrosis factor therapy abrogates autoimmune demyelination

1991 • 434 citations

Neurological sequelae of cerebral malaria in children

1990 • 402 citations

Human Cerebral Malaria *

1988 • 345 citations

Microvascular Sequestration of Parasitized Erythrocytes in Human Falciparum Malaria: a Pathological Study

1991 • 317 citations

Tumor‐Necrosis Factor and other Cytokines in Cerebral Malaria: Experimental and Clinical Data

1989 • 264 citations

L3T4+ T lymphocytes play a major role in the pathogenesis of murine cerebral malaria.

1986 • 253 citations

The effect of oxygen on vasoformative cell division. Evidence that 'physiological hypoxia' is the stimulus for normal retinal vasculogenesis.

1995 • 244 citations

Glycosylphosphatidylinositol toxin of Plasmodium induces nitric oxide synthase expression in macrophages and vascular endothelial cells by a protein tyrosine kinase-dependent and protein kinase C-dependent signaling pathway.

1996 • 232 citations

Astrocytes in infectious and immune‐mediated diseases of the central nervous system

1993 • 217 citations

Hypothesis: A role for tumor necrosis factor in immune-mediated demyelination and its relevance to multiple sclerosis

1988 • 199 citations

The Pathology of Human Cerebral Malaria

1990 • 188 citations

Tumor necrosis factor-α in immune-mediated demyelination and Wallerian degeneration of the rat peripheral nervous system

1993 • 153 citations

Ultrastructural studies of the blood-retina barrier after exposure to interleukin-1 beta or tumor necrosis factor-alpha.

1994 • 147 citations

Cerebral malaria in inbred mice. I. A new model and its pathology

1982 • 146 citations

Pathology of fatal and resolvingPlasmodium bergheicerebral malaria in mice

1992 • 145 citations

Tumor Necrosis Factor and Severe Malaria

1991 • 144 citations

Breakdown of the blood-brain barrier in murine cerebral malaria

1988 • 141 citations

Human Cerebral Malaria

1987 • 135 citations

Ultrastructural concomitants of anoxic injury and early post-anoxic recovery in rat optic nerve

1992 • 117 citations

Cerebral Malaria

1978 • 116 citations

Ocular Fundus Findings in Malawian Children with Cerebral Malaria

1993 • 116 citations

Glial, vascular, and neuronal cytogenesis in whole-mounted cat retina

1997 • 113 citations

Circulating adhesion molecules and inflammatory mediators in demyelination

1995 • 113 citations

Vascular changes and their mechanisms in the feline model of retinopathy of prematurity.

1992 • 109 citations

VULNERABILITY OF NERVE FIBRES TO ISCHAEMIA

1991 • 107 citations

Retinal Hemorrhage, A Common Sign of Prognostic Significance in Cerebral Malaria *

1983 • 105 citations

Early activation of microglia in the pathogenesis of fatal murine cerebral malaria

1997 • 104 citations

Erythrocyte stages of Plasmodium falciparum exhibit a high nitric oxide synthase (NOS) activity and release an NOS-inducing soluble factor.

1995 • 103 citations

Early microvascular changes in murine cerebral malaria detected in retinal wholemounts.

1992 • 80 citations

Intraneural activated T cells cause focal breakdown of the blood-nerve barrier

1995 • 74 citations

Correlation between enhanced vascular permeability, up-regulation of cellular adhesion molecules and monocyte adhesion to the endothelium in the retina during the development of fatal murine cerebral malaria.

1996 • 73 citations

Tumour necrosis factor causes an increase in axonal transport of protein and demyelination in the mouse optic nerve

1992 • 65 citations

Serum tumor necrosis factor associated with malaria in patients in the Solomon Islands

1990 • 65 citations

Redistribution and degeneration of retinal astrocytes in experimental murine cerebral malaria: Relationship to disruption of the blood-retinal barrier

1996 • 63 citations

Immunopathological aspects of Plasmodium berghei infection in five strains of mice. II. Immunopathology of cerebral and other tissue lesions during the infection.

1980 • 59 citations

Morphological changes in oligodendrocytes in the intact mouse optic nerve following intravitreal injection of tumour necrosis factor

1994 • 58 citations

Comparisons between microvascular changes in cerebral and non-cerebral malaria in mice, using the retinal whole-mount technique

1993 • 52 citations

Spatial Distribution of Nerve Injury after Occlusion of Individual Major Vessels in Rat Sciatic Nerves

1993 • 51 citations

Growth of injured rabbit optic axons within their degenerating optic nerve

1990 • 47 citations

Pathology of Falciparum Malaria in Vietnam

1992 • 43 citations

Cerebral malaria in the United Kingdom.

1979 • 39 citations

Subperineurial demyelination associated with reduced nerve blood flow and oxygen tension after epineurial vascular stripping.

1991 • 36 citations

The Diagnostic Histopathologic Features of Ocular Malaria

1993 • 36 citations

LESIONS IN THE BRAIN ASSOCIATED WITH MALARIA

1945 • 33 citations

Cerebral Malaria

1974 • 24 citations

Morphometry of unmyelinated nerve fibers.

1989 • 23 citations

Degeneration of axons in the corticospinal tract secondary to spinal cord ischemia in rats

1995 • 21 citations

Neurological sequelae of cerebral malaria

1996 • 14 citations

Retinopathy in malaria.

1982 • 12 citations

Cerebral vascular damage in guinea-pigs induced by various heterophile antisera injected by the Forssman intracarotid technique.

1961 • 12 citations