Effect of acute and chronic tramadol on [3H]-norepinephrine-uptake in rat cortical synaptosomes

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Synthetic analgesics. II. Dithienylbutenyl- and dithienylbutylamines.

1953 • 1,702 citations

Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic.

1992 • 1,138 citations

Pharmacology of spinal adrenergic systems which modulate spinal nociceptive processing

1985 • 586 citations

Tramadol

1993 • 538 citations

Direct evidence that spinal serotonin and noradrenaline terminals mediate the spinal antinociceptive effects of morphine in the periaqueductal gray

1979 • 478 citations

Serotonin and norepinephrine uptake inhibiting activity of centrally acting analgesics: structural determinants and role in antinociception.

1995 • 362 citations

Receptor binding, analgesic and antitussive potency of tramadol and other selected opioids.

1988 • 296 citations

The Use of Antidepressants in the Treatment of Chronic Pain

1991 • 251 citations

Interaction of the central analgesic, tramadol, with the uptake and release of 5‐hydroxytryptamine in the rat brain in vitro

1992 • 241 citations

Abuse potential and pharmacological comparison of tramadol and morphine

1991 • 235 citations

The analgesic effect of amitriptyline on chronic facial pain

1987 • 225 citations

Postoperative Patient-Controlled Analgesia with Tramadol: Analgesic Efficacy and Minimum Effective Concentrations

1990 • 203 citations

Influence of tramadol on neurotransmitter systems of the rat brain.

1996 • 177 citations

Peripheral nociceptive effects of α2-adrenergic receptor agonists in the rat

1995 • 122 citations

Intravenous Morphine Increases Release of Nitric Oxide From Spinal Cord by an α-Adrenergic and Cholinergic Mechanism

1997 • 77 citations

Effects of the analgesic agent tramadol in normal and arthritic rats: comparison with the effects of different opioids, including tolerance and cross-tolerance to morphine

1991 • 70 citations

Pharmacological treatment of neuralgic and neuropathic pain.

1988 • 59 citations

Effect of acute and chronic tramadol on [³H]‐5‐HT uptake in rat cortical synaptosomes

1997 • 55 citations

Inhibition of spinal noradrenaline uptake in rats by the centrally acting analgesic tramadol

1994 • 51 citations

Long-term administration of the centrally acting analgesic tramadol did not induce dependence or tolerance

1987 • 23 citations

[Examination of psychic effects of a new analgesic agent of the cyclohexanols series. A contribution to a possible psychic dependence potential of tramadol (author's transl)].

1978 • 6 citations